Egg whites may be perfect for a health-conscious breakfast, but egg yolks turned out to be the key ingredient for cultivating bird embryonic stem cells (ESCs) in the lab. Using a growing medium of egg yolk along with a few ...
Cell & Microbiology
15 hours ago
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A new tool greatly improves scientists' ability to identify and study proteins that regulate gene activity in cells, according to research led by Weill Cornell Medicine investigators. The technology should enable and enhance ...
Biotechnology
Sep 29, 2025
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By tracking the fate of individual embryonic stem cells, researchers have found that endoderm cells—early embryonic cells that give rise to tissues such as the gut and lungs—originate from multiple converging developmental ...
Cell & Microbiology
Sep 10, 2025
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Researchers from Japan and France have successfully reconstituted the development of mouse egg cells, known as oocytes, from embryonic stem cells entirely in vitro, without the need for ovarian support cells. This new method ...
Cell & Microbiology
Jul 22, 2025
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Sensorineural hearing loss (SNHL) is the most prevalent form of permanent hearing loss, affecting over 6% of the global population, according to the World Health Organization. It results from damage to sensory hair cells ...
Bio & Medicine
Jun 24, 2025
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The stem cell-based embryo model (SCBEM) takes advantage of the flexibility of pluripotent stem cells (non-reproductive cells that can give rise to many different types of cells) to resemble that of embryos. While this model ...
Cell & Microbiology
Jun 10, 2025
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Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization. ...
Cell & Microbiology
May 15, 2025
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Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology. Pluripotent stem cells (PSCs) have been invaluable tools in this field, as ...
Cell & Microbiology
Apr 25, 2025
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In a new study, researchers from the University of Copenhagen have successfully created stem cells that are better at developing into other cell types, like a younger, fitter version of themselves—by changing their diet. ...
Cell & Microbiology
Apr 25, 2025
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Glycolysis is an ancient metabolic activity. It consists of a set of reactions that convert glucose into energy. This central process allows cells to grow, divide, and stay alive. It has accompanied life since its origin, ...
Cell & Microbiology
Apr 16, 2025
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Embryonic stem cells (ES cells) are stem cells derived from the inner cell mass of an early stage embryo known as a blastocyst. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells.
Embryonic Stem (ES) cells are pluripotent. This means they are able to differentiate into all derivatives of the three primary germ layers: ectoderm, endoderm, and mesoderm. These include each of the more than 220 cell types in the adult body. Pluripotency distinguishes ES cells from multipotent progenitor cells found in the adult; these only form a limited number of cell types. When given no stimuli for differentiation, (i.e. when grown in vitro), ES cells maintain pluripotency through multiple cell divisions. The presence of pluripotent adult stem cells remains a subject of scientific debate; however, research has demonstrated that pluripotent stem cells can be directly generated from adult fibroblast cultures.
Because of their plasticity and potentially unlimited capacity for self-renewal, ES cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease. However Diseases treated by these non-embryonic stem cells include a number of blood and immune-system related genetic diseases, cancers, and disorders; juvenile diabetes; Parkinson's; blindness and spinal cord injuries. Besides the ethical concerns of stem cell therapy (see stem cell controversy), there is a technical problem of graft-versus-host disease associated with allogeneic stem cell transplantation. However, these problems associated with histocompatibility may be solved using autologous donor adult stem cells or via therapeutic cloning.
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