Every time a eukaryotic cell divides, it faces a monumental challenge: It must carefully duplicate and divide its genetic material (chromosomes) equally, and then rebuild the nuclear envelope around the separated halves. ...
Cell & Microbiology
Sep 23, 2025
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25
Harvard University researchers at the Broad Institute report that expansion in situ genome sequencing (ExIGS) linked nuclear abnormalities to hotspots of aberrant chromatin regulation, potentially eroding cell identity. The ...
Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules into and out of the nucleus. This microscopic metropolis relies on an intricate gateway—facilitated ...
Cell & Microbiology
Mar 20, 2025
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0
The biological factory that produces reproductive cells has a robust quality control system to identify and eliminate eggs with chromosomal abnormalities. For years, cell biologists have sought to uncover the mechanisms behind ...
Molecular & Computational biology
Dec 19, 2024
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13
A team of scientists studying cell division developed a special light microscopy system and used it to analyze the molecular density of cellular environments. Their results provide a novel insight into mitotic chromosome ...
Cell & Microbiology
Aug 28, 2024
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2
Researchers at Utrecht University in the Netherlands have identified a new way in which the toxic protein aggregates associated with Huntington's disease may damage nerve cells and cause them to die.
Cell & Microbiology
Aug 16, 2024
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82
Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.
Cell & Microbiology
Apr 17, 2024
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145
Each year, about 1 million individuals worldwide become infected with HIV, the virus that causes AIDS. To replicate and spread the infection, the virus must smuggle its genetic material into the cell nucleus and integrate ...
Cell & Microbiology
Jan 25, 2024
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9
Researchers at ETH Zurich recently identified a previously unknown compartment in mammalian cells. They have named it the exclusome. It is made up of DNA rings known as plasmids. The researchers have published details of ...
Cell & Microbiology
Oct 2, 2023
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716
Misfolded proteins are toxic to cells. They disrupt normal functions and cause some age-related human degenerative diseases, like Alzheimer's, Parkinson's, and Huntington's diseases. Cells work constantly to eliminate misfolded ...
Cell & Microbiology
Apr 20, 2023
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