During DNA replication, the classic double helix can temporarily rearrange into an alternative structure known as a DNA three-way junction (3WJ). These configurations form a well-defined central cavity capable of hosting ...
Biochemistry
Jul 23, 2025
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An easy method for efficiently identifying proteins that interact with bioactive molecules has been developed by chemical biologists at RIKEN. This innovation, published in ChemBioChem, could help to speed up the development ...
Molecular & Computational biology
Jul 15, 2025
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Professor Hirohide Saito and his research team have developed a new microRNA-responsive hybrid mRNA switch, enabling precise, tissue-specific control of protein expression and pushing the potential of mRNA-based therapeutics.
Biotechnology
Jul 7, 2025
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A University of California, Riverside-led team has made an advance in the basic understanding of Plasmodium falciparum, the parasite responsible for the deadliest form of human malaria, that could make novel, highly targeted ...
Cell & Microbiology
Jul 1, 2025
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Using advanced artificial intelligence, researchers have developed a novel method to make drug development faster and more efficient.
Biotechnology
May 12, 2025
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Cell-free systems, which can express an easily detectable protein with a DNA or mRNA template without constraints of living cells, are attractive as foundations for biosensors. Moreover, by encapsulating them in lipid bilayer ...
Cell & Microbiology
Mar 27, 2025
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Most cells in the body send out little messengers called extracellular vesicles that carry proteins, lipids, and other bioactive molecules to other cells, playing an important role in intercellular communication. But healthy ...
Bio & Medicine
Mar 14, 2025
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51
Protein kinase research presents an opportunity to explore molecular targets in the body to treat diseases like cancer and autoimmune disorders. These enzymes have the potential to bind to cellular sites and inhibit dysfunctional ...
Molecular & Computational biology
Mar 11, 2025
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The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness their powers, scientists are searching for ...
Biotechnology
Feb 17, 2025
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In a pioneering collaboration with AbbVie, Northwestern researchers have discovered a new way to potentially treat cancer by targeting and removing harmful proteins from cells.
Biochemistry
Feb 13, 2025
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