Visualizing small proteins – a crucial part of understanding disease drivers – has long been one of the toughest challenges in cryo-electron microscopy. Our scientists have overcome this obstacle by developing “Rigid Fabs,” a groundbreaking innovation which can transform antibody fragments into rigid scaffolds, making it possible to capture high-resolution images of small proteins. The video shows we are able to resolve small proteins to high resolution by cryoEM using our newly developed technology. Read more about this advancement in Nature Communications to learn how this technology is paving the way for accelerated drug discovery. http://spr.ly/6040A9no6
Way to go Jen!
Pioneering research that will improve health outcomes for all
😍
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14hRigid Fabs represent a structural biology breakthrough—enabling high-resolution cryo-EM of small proteins that previously evaded characterization. 🎯🔬 #StructuralBiology #DrugDiscovery