A simple vision test could detect Alzheimer's up to 12 years before memory loss begins. Yes, there is strong evidence that a simple vision test could detect Alzheimer’s up to 12 years before memory loss begins. Optical Coherence Tomography Angiography (OCTA) to identify early retinal vascular changes associated with the disease. One of the most notable studies, published in the journal Neurology, involved over 8,000 cognitively healthy participants. They took a visual sensitivity test, where they had to press a button as soon as they saw a triangle appear in a field of moving dots. Those who later developed dementia performed significantly worse on the test compared to those who remained healthy. The research suggests that visual impairments could be early indicators of cognitive decline, possibly because the amyloid plaques associated with Alzheimer’s may first affect the brain regions tied to vision. In addition, other visual deficits like difficulty distinguishing certain colors or controlling eye movements have also been identified as early signs. For further details, you can check out the full article from the New York Post, which explains the “triangle test” and how it caught Alzheimer’s 12 years early: https://lnkd.in/gNJ9Vf3B This growing body of evidence suggests that vision tests may one day become a standard tool for early Alzheimer’s detection.
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🧠 World Alzheimer’s Day Hot of the press results from out partner Quantified Imaging prove the potential of ASL MRI for dementia research. We offer powerful imaging methods and analysis to support treatment response evaluation in clinical trials for Alzheimer’s disease. ✅ASL MRI shows strong correlation between perfusion change and cognitive improvement under Lecanemab therapy — outperforming volume-based metrics. ✅Baseline prediction highlights ASL’s potential to identify responders before treatment begins. 💡 A non-invasive, cost-effective alternative to PET — ideal for clinical trials and routine care. #WorldAlzheimersDay #ASLMRI #DementiaResearch #Neuroimaging #ClinicalTrials #BrainHealth
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🧠 New MRI Technique May Predict Alzheimer’s Risk Researchers at Johns Hopkins have developed a specialized MRI method that can detect iron levels in the brain — a potential early warning sign of Alzheimer’s disease. High brain iron has been linked to increased toxins and neurodegeneration, particularly when combined with amyloid and tau proteins, the hallmark indicators of Alzheimer’s-related cognitive decline. Learn more: 👉 https://lnkd.in/gUqASD-A #Alzheimers #MRIscan #BrainHealth
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Researchers at Lund University in Sweden have developed a digital cognitive test for diagnosing Alzheimer's disease that is intended for use in primary care. “This digital test, which patients perform on their own with minimal involvement from healthcare personnel, improves the primary care physician's ability to determine who should be further examined by blood tests for Alzheimer's pathology early in the investigation phase,” says Professor Oskar Hansson, who led the study alongside Pontus Tideman. “Primary care does not have the resources, time or specialist knowledge to investigate possible Alzheimer's disease in the same way as specialised memory clinics. And this is where a digital cognitive test can make the biggest difference,” says Oskar Hansson, professor of neurology at Lund University. Research supported by Knut and Alice Wallenberg Foundation https://lnkd.in/d8gDkQKs #research #medicine #Alzheimers #Alzheimer Lund University Oskar Hansson
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A new blood test for #Alzheimer’s is being trialled across 20 #NHS memory clinics in the UK, aiming to boost diagnostic accuracy from 70% to over 90%. Led by UCL and backed by Alzheimer's Society and Alzheimer's Research UK, this could transform early detection and care. Learn more: https://lnkd.in/e5sjj_Vx #Diagnostics #Alzheimers #DementiaAwareness #HealthcareInnovation #MedicalResearch #UCL #Biomarkers #EarlyDiagnosis #Neuroscience #ADAPTTrial
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Impressive work here! "Neurological conditions, including dementia, pose a major public health challenge, contributing to a significant and growing clinical, economic, and societal burden. Traditionally, research and clinical practice have focused on diseases like dementia in isolation. However, in an ageing, multimorbid population, this approach is becoming increasingly inadequate. Recognising brain health as a lifelong attribute influenced by various health determinants, this paper explores the concept of brain health, identifies key challenges in assessing it effectively, and examines how digital biomarkers could provide a versatile measurement framework to enhance monitoring and facilitate earlier intervention. Finally, we outline future directions to help advance definitions of meaningful aspects of brain health integration, and practical adoption of digital biomarkers, enhancing our capacity to measure and preserve ‘brain health capital’ or ‘brain span’ across the lifecourse." Kelly O'Brien Connor McLaughlin George Vradenburg Andy Moose Agustin Ibanez Kana Enomoto Lucy Perez Erica Hutchins Coe Jochen Reiser, M.D., Ph.D. The University of Texas Medical Branch Amy Dittmar Adrian Trömel https://lnkd.in/gxAViT7R
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Brain health is rarely about one single thing. For those just starting to notice changes, or for caregivers supporting a loved one, it often comes down to a mix of medical, lifestyle, and social factors all working together. Digital tools like diagnostics, wearables, and mobile health platforms are starting to give us a more complete picture. But the real value is not in the data alone. It is in how we use that information to set meaningful goals for people and their families. Research shows that up to 45 percent of dementia cases could be delayed or even prevented through early intervention. This is where the brain–body connection becomes so important, especially for those beginning to experience change. In dementia, it is rarely one physical cause. It is often many factors that shape daily life and wellbeing. That is why integrated and comprehensive care matters most. Thanks for the share Harris Eyre Dilpriya K. Mangat MD FRCPC MBA NexCerebrum
Advancing the Brain Economy 🌎🧠 Senior Fellow at Rice University and UTMB, Visiting Senior Fellow at Wharton Neuroscience, Senior Advisor at McKinsey & Company
Impressive work here! "Neurological conditions, including dementia, pose a major public health challenge, contributing to a significant and growing clinical, economic, and societal burden. Traditionally, research and clinical practice have focused on diseases like dementia in isolation. However, in an ageing, multimorbid population, this approach is becoming increasingly inadequate. Recognising brain health as a lifelong attribute influenced by various health determinants, this paper explores the concept of brain health, identifies key challenges in assessing it effectively, and examines how digital biomarkers could provide a versatile measurement framework to enhance monitoring and facilitate earlier intervention. Finally, we outline future directions to help advance definitions of meaningful aspects of brain health integration, and practical adoption of digital biomarkers, enhancing our capacity to measure and preserve ‘brain health capital’ or ‘brain span’ across the lifecourse." Kelly O'Brien Connor McLaughlin George Vradenburg Andy Moose Agustin Ibanez Kana Enomoto Lucy Perez Erica Hutchins Coe Jochen Reiser, M.D., Ph.D. The University of Texas Medical Branch Amy Dittmar Adrian Trömel https://lnkd.in/gxAViT7R
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Researchers at Lund University in Sweden have developed a digital cognitive test for diagnosing Alzheimer's disease that is intended for use in primary care. “This digital test, which patients perform on their own with minimal involvement from healthcare personnel, improves the primary care physician's ability to determine who should be further examined by blood tests for Alzheimer's pathology early in the investigation phase,” says Professor Oskar Hansson, who led the study alongside Pontus Tideman. “Primary care does not have the resources, time or specialist knowledge to investigate possible Alzheimer's disease in the same way as specialised memory clinics. And this is where a digital cognitive test can make the biggest difference,” says Oskar Hansson, professor of neurology at Lund University. Research supported by Knut and Alice Wallenberg Foundation https://lnkd.in/diQQeBeS #research #medicine #Alzheimers #Alzheimer Lund University Oskar Hansson
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UCI MIND researchers have received an $18 million, five-year grant from the National Institute on Aging (NIA) to conduct a landmark multi-center study on dementia. The award highlights UC Irvine's position as a global leader in Alzheimer's disease and related dementias research. The project will establish the nation's first trial-ready patient group for limbic predominant age-related TDP-43 encephalopathy (LATE), a common but underrecognized condition present in up to 40 percent of older adults' brains. “This study will advance efforts to develop accurate diagnostic tools for LATE and lay the foundation for recruiting participants into future clinical trials targeting this disease,” says S. Ahmad Sajjadi, M.D., Ph.D., associate professor of neurology in the UC Irvine School of Medicine. More: https://bit.ly/465Rl7C UC Irvine School of Medicine
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💡 The Eyes That Speak Before the Brain Groundbreaking research in mice reveals that changes in retinal blood vessels mirror early Alzheimer’s disease processes in the brain. Why this matters: ✅ Eye exams are quick, painless, and non-invasive ✅ Potential for earlier detection and intervention ✅ Could reshape dementia diagnosis and care pathways While human studies are still needed, this could mark a turning point in how we fight neurodegenerative disease. #Alzheimers #DementiaResearch #HealthcareInnovation #Neurology https://lnkd.in/gmueWVZe
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How can we accelerate motor recovery after stroke? 🧠 I’m excited to share our latest viewpoint article in eClinical Medicine, where we propose a promising approach. 🧠 The Problem: Stroke is a leading cause of long-term disability, and current rehabilitation methods often have limited efficacy. 🧠 Our Viewpoint: We propose using cortico-cortical paired associative stimulation (ccPAS), an advanced non-invasive brain stimulation technique to promote neural plasticity in cortical networks after stroke 🧠 The Innovation: Unlike traditional methods, ccPAS allows us to precisely manipulate specific neural pathways to create truly personalised interventions tailored to each patient's needs. This work is a key step in translating cutting-edge neuroscience into potential clinical solutions for post-stroke motor rehabilitation. Read the full article for more insights: https://lnkd.in/dc78PxQr This work was supported by The Academy of Medical Sciences, The University of Essex and ESNEFT #StrokeRehabilitation #BrainPlasticity #MedicalResearch #Neurology
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