Burst suppression is not sleep. Its 🧠 shutdown. 👉 Burst Suppression matters! 🗣️ Avoid it if possible, especially in vulnerable brains. 👀 at the raw EEG! Narrative Review by: Anita Jegari, Maria Walline, Peter A. Goldstein & Seyed Safavynia. https://lnkd.in/drzqF8AF #anesthesia #neuromonitoring #EEG #delirium #patientSafety
No place for BS. It's a sign of unnecessary depth. I requested SR to be put in the EHR Safersleep record years and years ago at #TeWhatuOra. Hopefully they start to audit Safersleep and practice scientifically. That was certainly not happening which is why I resigned in Dec2023. Audit & track your outcomes for best patient outcomes.
Strong piece, Max. Even if large RCTs are inconsistent, the experimental and human data repeatedly link intraop burst suppression to neurologic vulnerability and worse cognition, so at the bedside I treat BSP as a dose-limiting toxicity. Read raw EEG + DSA and avoid BSP whenever possible, especially in older or frail brains. 🧠
The association of burst suppression with POD/POCD is interesting and many question still need answering. In particular, despite the association, the causal relationship is far from being fully understood. Is BS causing poor neurocognitive outcomes, which can be diminished by careful hypnotic titration? Or is BS only a marker, helping unmask brain frailty? Or maybe both. There seems to be some high-risk groups for which BS is a more omnious sign, like when it occurs at “normal” or low hypnotic doses. In others, like young and healthy patients with BS resulting from “only” hypnotic overdose will show no measurable cognitive consequences. One promising avenue is looking at brain energy metabolism : frail brains at risk of POD/POCD often have a limited energy metabolism reserve and can easily suffer from an energy deficit when exposed to anesthesia and surgery.
Anesthésiste-Réanimateur, Hôpital Lariboisière
1wIt's interesting to look more closely at the mechanisms behind burst suppression. Burst suppression can result from overdosing of hypnotics or decrease of cerebral blood flow and it's difficult to tell these two mechanisms apart with EEG. Often these two causes are mixed because most hypnotics cause hypotension. Is an excessive dose of hypnotics harmful if blood pressure is controled? A part from delayed recovery, I'm not convinced it has long lasting negative effects. However brain hypoperfusion is very bad. In practice there is no easy way to explore the autoregulation capacity of a given patient. Who hasn't experienced this: you give noradrenaline and the patient wakes up. This is why Elsa Manquat worked on ways go distinguish between perfusion and hypnosis