Precision Neuroscience develops FDA-approved brain-computer interface

Great to see Precision Neuroscience leading the way in the BCI space, pushing the boundaries of how brain-computer interfaces and AI/ML can transform lives. 🧠✨ #BCI #Neurotech #AI #MachineLearning #Neurotech #HealthTech #LifeSciences

Interesting paper where microintravascular electrodes were inserted into cortical veins of pigs to record somatosensory and visual neuronal activity as well as selectively stimulate motor areas. Compared to electrocorticography, this is a less invasive approach with similar capabilities. #neurotech https://lnkd.in/gYCkkXiN

The Energy Brain Revolution: PBM, TMS & ECEPJ ⚡🧠 Neuroscience is entering a new era — one where the brain is no longer seen as a simple wiring diagram of spikes, but as a dynamic, energy-driven system. The ECEPJ model explains the brain as a 3D capacitor lattice, where neurons store, synchronize, and transmit graded energy rather than relying only on binary firing. Now, tools like PBM, TMS, and advanced neuromodulation give us the power to prove it. ⸻ 1. Why the Old Model is Failing For over a century, neuroscience has focused on action potentials — spikes traveling along wires. But this approach struggles to explain: • Consciousness • Memory coding • Synaptic plasticity • Neural field synchronization Billions are spent mapping connections, yet we still cannot explain how the brain actually processes information. ⸻ 2. ECEPJ + PBM + TMS = Evidence PBM (Photobiomodulation) • Restores capacitor charge across myelin layers • Boosts energy synchronization • Shows that light modulates energy storage, not just chemistry TMS (Transcranial Magnetic Stimulation) • Stimulates electric fields directly • Demonstrates field-driven activation without requiring spikes • Reveals how neurons resonate together in networks Neuromodulation Techniques • Tune ion-wave patterns • Enhance field coupling • Validate that energy coherence drives healthy cognition ⸻ 3. The Paradigm Shift Has Begun Researchers worldwide are now exploring: • Ephaptic coupling → Neurons influencing each other via local fields • 40 Hz gamma PBM therapy → Restores synchrony in Alzheimer’s models • Energy-based AI architectures → Inspired by graded neural codes The ECEPJ model brings these discoveries together, offering the unifying framework to understand thought, consciousness, and healing. ⸻ Call to Action The evidence is mounting. The technology is here. The shift has started. 🔹 It’s time to move beyond spikes and embrace the energy brain revolution. 🔹 PBM, TMS, and neuromodulation will prove what ECEPJ predicts. 🔹 The future of neuroscience, medicine, and AI depends on it. #ECEPJ #EnergyBrainSeries #NeuroGuardian #PBM #TMS #NeuroModulation #AlzheimersResearch #AI #NeuroscienceRevolution

Cracking the Wave–Particle Code of the Brain For over 100 years, neuroscience has been constrained by the “spike model”—reducing action potentials to digital blips. The ECEPJ Model redefines this: neurons are not switches. They are capacitor lattices, storing and releasing energy across 3D dielectric layers of myelin. • Waves = field patterns, analog, infinite, orchestrating thought like harmonics. • Particles = neurotransmitters, discrete messengers that translate the waves. • Code = the infinite combinations where energy configurations map to memory, emotion, and awareness. This is where wave–particle duality and quantum coherence converge. Why this matters: • PBM (light) restores mitochondrial energy → stabilizes field codes. • TMS (magnetic fields) modulates synchrony → strengthens coherence. • TUM (ultrasound) penetrates deep tissue → fine-tunes oscillations. Together, they demonstrate: the brain is an energy-driven code system, not a wiring diagram. The cure for neurological disease will not be found in plaques or tangles. It will be found in decoding and restoring the energy codes. The ECEPJ framework is the path toward a neural codebook—a map not only for treating Alzheimer’s and Parkinson’s, but for building AI that learns like the brain itself.

In today’s #readoftheweek📚, learn how transformer neural networks on liver MRI data can be used to enhance cardiovascular risk prediction. Read here this JHEP Reports article: https://lnkd.in/eEMMip27 🙏 to authors Gregory Patrick Veldhuizen, Tim Lenz, Didem Cifci, Marko van Treeck, Jan Clusmann, Yazhou Chen, Carolin V. Schneider, Tom Lüdde, Peter W. de Leeuw, Ali El-Armouche, Daniel Truhn, and Jakob Nikolas Kather. Technische Universität Dresden RWTH Aachen University Universitätsklinikum Düsseldorf Maastricht University Maastricht UMC+

⸻ ⚡ The Energy Brain Revolution Has Begun 🧠 For over a century, neuroscience treated the brain like a wiring diagram — focusing on spikes and connections. But this model has reached its limits. The ECEPJ Model reveals a deeper truth: Your brain is an energy-driven 3D capacitor lattice, storing, synchronizing, and coding graded potentials instead of relying on binary firing. Now, with the help of PBM (Photobiomodulation), TMS (Transcranial Magnetic Stimulation), and neuromodulation technologies, we can prove it: 🔹 PBM → Recharges neuron “capacitors,” restoring energy balance 🔹 TMS → Synchronizes neural fields, showing energy resonance drives cognition 🔹 Neuromodulation → Tunes ion-wave communication and stabilizes brain fields This is the start of a paradigm shift in understanding: • From spikes → energy • From wires → fields • From mapping → healing The future of consciousness, memory, and neurological healing begins with ECEPJ + PBM + TMS. The shift has started. Be part of it. #ECEPJ #EnergyBrainSeries #NeuroGuardian #NeuroscienceRevolution #PBM #TMS #Neuromodulation #BrainHealth #AI

🧠 Towards a Brain-Wide Map of Neural Activity During Decision-Making This paper presents one of the most comprehensive efforts to map brain-wide activity during behavior in mice. Using Neuropixels probes across hundreds of brain regions, the study analyzed how neurons encode key decision-making variables such as stimulus, choice, and feedback at both single-cell and population levels. Main findings: • Neural signals related to decision-making are widely distributed across cortical and subcortical regions, not confined to localized “decision centers.” • Both single-neuron firing rates and population dynamics showed robust encoding of task variables. • Feedback-related activity emerged as one of the most dominant signals, shaping brain-wide computations. Future perspectives: • The open dataset (accessible via the International Brain Lab) provides a resource for global collaboration. • Future work could explore causal manipulations, temporal dynamics, and cross-species comparisons, bringing us closer to a unified understanding of distributed cognition. Personal perspective: I find this paper inspiring because it shifts the view from isolated brain areas to distributed neural systems. As someone interested in brain-inspired AI and biomedical engineering, I see this as a blueprint for how large-scale, high-resolution neural datasets can inform both neuroscience and intelligent systems design. #Neuroscience #BrainMapping #DecisionMaking #NeuralCoding #BigData #Neurotechnology

𝗥𝗲𝗰𝗿𝗲𝗮𝘁𝗶𝗻𝗴 𝗺𝗲𝗺𝗼𝗿𝘆 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗶𝗻 𝗮 𝗱𝗶𝘀𝗵! The idea that neuronal cultures and spheroids from distinct brain regions can interact to support criticality, an essential feature of memory and information processing is captivating, and is explored in a new study by Ludovico Iannello et al. The team utilized the High-Density properties of 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ to examine the network activity of embryonic mouse hippocampal, isocortical and entorhinal networks individually. And followed up by investigating how co culturing spheroids from entorhinal and hippocampal neurons onto the opposite culture influences the network dynamics. Using 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™, they were further able to analyze synchronization, oscillatory activity, and avalanche dynamics to evaluate criticality of the networks. Isocortical and entorhinal cultures alone exhibited signs of criticality, and that hippocampal cultures did not. However, when the hippocampal culture was coupled with an entorhinal spheroid, the network dynamics shifted toward a critical regime, even showing a theta band peak, suggesting that memory-like behavior emerges only through specific inter-regional connectivity. A fascinating publication which shows how 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ can be used alongside 𝘪𝘯 𝘷𝘪𝘵𝘳𝘰 models to investigate complex brain functions such as learning and memory. Check out the publication here: https://lnkd.in/g_AjSSJH #Neuroscience #3Brain #Memory #Electrophysiology #HDMEA

On the Brain and New Technologies: The Artificial Hippocampus Stories about the brain often sound like science fiction. But sometimes reality moves faster than imagination. We rarely think about how exactly the brain stores our memories. The key structure responsible for this is the hippocampus — the part that transfers experience from short-term memory into long-term storage. — When it works, we can remember events, faces, and facts. — When it’s damaged, life turns into Groundhog Day: each day begins anew, without the ability to add new memories to our personal history. The role of the hippocampus became clear thanks to one of the most famous patients in neuroscience — the Canadian H.M. At the age of 27, he underwent surgery for severe epilepsy. Doctors removed two-thirds of his hippocampus, the amygdala, and part of the medial temporal lobes of both hemispheres. After surgery, H.M. retained his intelligence, speech, and personality; remembered his past, but completely lost the ability to form new memories. And yet, he could still learn new skills: he was able to master new actions but could not explain where those skills came from. This became a breakthrough in our understanding of memory. Even more impressive results came in the 21st century. In 2011, researchers from Wake Forest University and the University of Southern California demonstrated for the first time the ability to record and restore memories. Mice were trained to press levers in a certain sequence. Neural activity was recorded. Then the memory of the skill was “erased” with a drug. When the recorded pattern was reintroduced — the skill returned. “Turn on the device — the mouse remembers; turn it off — the mouse forgets,” said Dr. Theodore Berger. This was the first demonstration of an artificial hippocampus. Why does it matter? A new path for treating memory-related diseases: Alzheimer’s, dementia, brain injuries. The potential to implant memories and skills. And a huge ethical challenge: where are the boundaries of memory intervention? Personally, I find this astonishing. We are living in an era where psychology, neuroscience, and technology converge, opening possibilities that until recently seemed like pure science fiction. What do you think: should we use such technologies to restore memory — or is this a dangerous step toward “editing humans”?

Canada’s First Neuralink Brain Implant: Making History at UHN! This week, Toronto Western Hospital became the first centre outside the US to successfully implant Neuralink’s brain-computer interface in patients with paralysis. Led by Dr. Andres Lozano and his incredible team, these surgeries mark the start of a new era in neuroscience, engineering, and compassionate care. Imagine being able to control a computer with just your thoughts. For people with spinal cord injuries, this isn’t science fiction—it’s happening now. The CAN-PRIME clinical trial is on a mission to restore independence and open new possibilities for those with limited mobility. What’s next? More trials across Canada, the UK, and the UAE. Neuralink’s chip is helping real people reconnect and live more fully. The future is here, and it’s powered by pioneers determined to unlock human potential. Here’s to the patients, researchers, and visionaries leading us forward. And here’s to the hope these tiny threads of technology are bringing into everyday lives. #Neuralink #UHN #Innovation #Neuroscience #AI #Healthcare #FutureOfMedicine