Cyprotex Highlights - Q2 2025
Catch up on all the latest news and developments from Cyprotex, your ADME-Tox specialists!
FDA recently published "Roadmap to Reducing Animal Testing in Preclinical Safety Studies", which outlines a strategic plan to decrease reliance on animal testing by integrating New Approach Methodologies (NAMs). Cyprotex welcomes this move, a direction that perfectly aligns with our 25-year dedication to ethical research and the 3Rs (Replacement, Reduction, Refinement). As part of this commitment, Cyprotex and its parent company, Evotec, have invested strategically over many years in NAMs, including human-based in vitro systems like organoids, sophisticated in silico modeling, AI/ML and other innovative platforms.
We are committed to work with partners, regulatory bodies, and stakeholders to embrace the concepts outlined in the FDA roadmap and continue to drive ethical, innovative, scientifically rigorous safety assessment strategies for the delivery of safe, effective medicines to the clinic.
Even the most sophisticated AI/ML models are only as good as the data behind them. That’s why we deliver high-quality, standardized ADME-Tox datasets essential for training robust machine learning models. Our scalable, high-throughput platforms ensure data precision, reproducibility, and rapid turnaround, helping AI-driven teams turn virtual predictions into real-world breakthroughs.
Curious how we can accelerate your AI-driven drug discovery projects?
We published a blog post recently that delves into the critical role of MRP transporters in the context of statin-induced myopathy. This insightful piece builds on recent research, highlighting how MRP1, MRP4, and MRP5 may offer protection against muscle toxicity by effluxing statins from myocytes. Discover how a deeper understanding of transporter-mediated drug interactions can inform safer therapeutic strategies for patients on statin therapy.
Did you know Cyprotex offers multiple in vitro and in chemico skin sensitization assays, including DPRA, KeratinoSens™ and U-SENS™ to evaluate the sensitization potential of chemicals, cosmetics, and pharmaceuticals? These rigorous, OECD-compliant protocols deliver high-quality data to support regulatory submissions and product safety, while reducing reliance on animal testing.
Read more from Evotec, Cyprotex and Just - Evotec Biologics in our scientific resource hub - Science Pool:
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