A Light-Powered Lifeline: World’s Smallest Pacemaker Offers Big Hope for Tiny Hearts

Unprecedented Miniaturization and Design

This pacemaker is exceptionally compact, measuring just 1.8 millimeters in width, 3.5 millimeters in length, and 1 millimeter in thickness—smaller than a grain of rice. Its diminutive size enables non-invasive implantation via a syringe, minimizing trauma to delicate tissues. Crafted from biocompatible, bioresorbable materials, the device naturally dissolves in the body after approximately seven days, eliminating the need for surgical removal and reducing potential complications.

Innovative Light-Activated Functionality

Departing from traditional pacemakers that rely on wires and external power sources, this novel device operates in conjunction with a soft, flexible, wireless wearable device affixed to the patient's chest. Upon detecting an irregular heartbeat, the wearable emits a light pulse that penetrates the skin to activate the pacemaker, which then delivers an electrical impulse to regulate the heart's rhythm. This light-based activation allows for precise, wire-free control, enhancing patient comfort and safety. Northwestern Now

Addressing a Critical Need in Pediatric Care

Congenital heart defects affect approximately 1% of newborns, many of whom require temporary cardiac pacing following surgery. Traditional temporary pacemakers often involve external wires, posing risks of infection and complications during removal. The development of this tiny, dissolvable pacemaker addresses these challenges, offering a safer and less invasive solution for managing postoperative arrhythmias in infants.

Check out the video about the pacemaker here: https://www.youtube.com/watch?v=j_0hZ8cUwgo

Potential for Broader Medical Applications

While currently designed for temporary use in newborns, the principles underlying this technology hold promise for broader medical applications. The integration of bioresorbable electronics and light-based activation could lead to advancements in adult cardiac care and other therapeutic areas, potentially transforming the landscape of implantable medical devices. Northwestern Now

This pioneering work by Northwestern University's engineering team represents a significant step forward in cardiac care, offering hope for safer and more effective treatments for patients with heart conditions.

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