From Molecular Genetics to Phylodynamics: Evolutionary Relevance of Mutation Rates Across Viruses
Figure 3
Expected relationship between mutation and evolution rates according to the neutral-deleterious evolution model for four human viruses: HCV (hepatitis C virus), PV-1 (poliovirus 1), FLUVA (influenza A virus), and HIV-1 (human immunodeficiency virus 1).
Curves indicate the prediction obtained using log10 a = 2.387, b = 3.744, and the corresponding genome size of each virus. White dots show the observed average rates. These four viruses were chosen for representation because of the relatively high number of estimates available (see [7] and Text S1). Fewer data are available for the other three viruses appearing in Figure 2a, and their predicted rates deviated more from the observed values.
doi: https://doi.org/10.1371/journal.ppat.1002685.g003