IRB Barcelona

🧪 Leading Spanish hospitals implement the MAF Test to revolutionize breast cancer treatment: Inbiomotion, the IRB Barcelona-ICREA spin-off, announces the launch of the MAF Test® in select hospitals across Barcelona and Madrid starting today 👇 ✅ Widespread adoption of the MAF Test® could significantly enhance survival rates for nearly 80% of the 33,000 early-stage breast cancer patients diagnosed annually in Spain, according to 2024 data from the Spanish Society of Medical Oncology (SEOM). ✅ The MAF Test® offers predictive insights into the prognosis of breast cancer patients, enabling oncologists to identify those who could benefit from adjuvant bisphosphonate treatment (commonly used for osteoporosis) to prevent metastasis. Additionally, it helps pinpoint patients whose prognosis may worsen with bisphosphonate treatment, sparing them from unnecessary, ineffective therapies. ✅ The MAF Test® is now available in Spain, Portugal, Italy, South Africa, and the UK. Discover more ➡️ https://bit.ly/46aE7XB 📍 Participating hospitals include: Hospital del Mar Hospital Clínic de Barcelona HM Hospitales IBCC - International Breast Cancer Center / PANGAEA ONCOLOGY Shaping the future of cancer care with: Inbiomotion Institució Catalana de Recerca i Estudis Avançats, ICREA Roger Gomis Joël Jean-Mairet Ralf van den Berg Juan Carlos Tercero Lopez ...and all the scientists who have contributed to making this possible. *** 🎥 Video credits: Telenotícies 3Cat Corporatiu #IRBInnovation #Innovation #BreastCancer #Cancer #CáncerDeMama #MAFTest #Oncology

🔬 El rol transformador de los organoides en la investigación médica: En la amplia trayectoria investigadora que se está llevando a cabo en el terreno de los organoides cabe destacar el buen posicionamiento de España gracias a aportaciones de investigadores como las del grupo liderado por el Prof. Eduard Batlle, del IRB Barcelona, pioneros en organoides de intestino humano junto con el biólogo molecular Prof. Hans Clevers y su laboratorio Hubrecht Institute (Países Bajos).  📰 IM Médico Lee el artículo completo aquí ➡️ https://shorturl.at/RfhdA Institució Catalana de Recerca i Estudis Avançats, ICREA CIBERONC #CancerResearch #ColonCancer #ColorectalCancer #Organoids #Organoides #Research

🤝 Meet Dr. Stefanie Kristin Wculek, a leading expert in innate immune biology 👇 ✅ Dr. Wculek developed an effective pre-clinical cancer immunotherapy based on a subset of dendritic cells as part of a large international consortium of industrial, clinical and basic scientists. ✅ Moreover, she discovered metabolic differences of tissue macrophages that depend on their organ of residence, which leads to therapeutically exploitable vulnerabilities of those cells. ✅ Overall, her work established the surprising diversity of functions and dependencies of dendritic cell and macrophage populations in vivo in health and non-infectious inflammatory diseases. In 2023, Dr. Wculek joined IRB Barcelona as Group Leader to head the Innate Immune Biology laboratory. 🎥 Meet her here! ▶️ https://lnkd.in/dHPkeTKN #IRBScience #MeetOurScientists #ImmuneSystem #Immunotherapy #InnateImmuneBiology #Research

💬 🔙 Hoy queremos invitarte a visualizar de nuevo nuestra Mesa Redonda: “Presente y Futuro de la Investigación del Cáncer de Mama”. Un encuentro inspirador que reunió a voces clave de la investigación, la medicina y la experiencia personal para abordar los retos y avances en la lucha contra el cáncer de mama👇 💬 Te invitamos a conocer las reflexiones de los ponentes sobre cómo la investigación transforma vidas: 🗣️ Dr. Roger Gomis — IRB Barcelona 🗣️ Dr. César Serrano — Hospital Universitari Vall d'Hebron/ Vall d'Hebron Institute of Oncology (VHIO) 🗣️ Carme Segura — Paciente de cáncer de mama 🎙️ Moderación a cargo de Michele Catanzaro, periodista científico. ¡No te la pierdas! 🔗 https://lnkd.in/epdtCh2g #BreastCancer #Cancer #CáncerdeMama #CancerResearch #Investigación #Research

📢 Dr. Salvador Aznar Benitah, Group Leader of the Stem Cells and Cancer laboratory at IRB Barcelona and ICREA Professor who specializes in cancer and stem cell research, was selected as one of the Cell Press 50 Scientists that Inspire for his paradigm-shifting work in cancer metabolism and aging research👇 Learn more about his work ▶️ https://lnkd.in/d-irwcNu Cell Press Institució Catalana de Recerca i Estudis Avançats, ICREA #50ScientistsThatInspire #CP50 #AgeingResearch #AgingResearch #CancerResearch #StemCellResearch #Research

🧪 Leading Spanish hospitals implement the MAF Test to revolutionize breast cancer treatment: Inbiomotion, the IRB Barcelona-ICREA spin-off, announces the launch of the MAF Test® in select hospitals across Barcelona and Madrid starting today 👇 ✅ Widespread adoption of the MAF Test® could significantly enhance survival rates for nearly 80% of the 33,000 early-stage breast cancer patients diagnosed annually in Spain, according to 2024 data from the Spanish Society of Medical Oncology (SEOM). ✅ The MAF Test® offers predictive insights into the prognosis of breast cancer patients, enabling oncologists to identify those who could benefit from adjuvant bisphosphonate treatment (commonly used for osteoporosis) to prevent metastasis. Additionally, it helps pinpoint patients whose prognosis may worsen with bisphosphonate treatment, sparing them from unnecessary, ineffective therapies. ✅ The MAF Test® is now available in Spain, Portugal, Italy, South Africa, and the UK. Discover more here ➡️ https://bit.ly/46aE7XB 📍 Participating hospitals include: Hospital del Mar Hospital Clínic de Barcelona HM Hospitales IBCC - International Breast Cancer Center/ PANGAEA ONCOLOGY Shaping the future of cancer care with: Inbiomotion Institució Catalana de Recerca i Estudis Avançats, ICREA Roger Gomis Joël Jean-Mairet Ralf van den Berg Juan Carlos Tercero Lopez ...and all the scientists who have contributed to making this possible. *** 🎥 Video credits: Telenotícies 3Cat Corporatiu (7/18/25) #IRBInnovation #Innovation #BreastCancer #Cancer #CáncerDeMama #MAFTest #Oncology

🤝 #IRBBarcelona Group Leader Cristina Mayor-Ruiz has co-authored a Perspective in #MolecularCell proposing the creation of a #EuropeanAlliance to accelerate the development of proximity-induced therapies. ➡️  These innovative therapies aim to harness molecular proximity to eliminate or modulate disease-related proteins that were previously considered undruggable. New tools, including AI and machine learning, are expected to help accelerate progress. 📝 The proposal was developed from six leading European institutions: Goethe University Frankfurt, CeMM, AITHYRA Research Institute for Biomedical Artificial Intelligence, University of Dundee, EPFL and #IRBBarcelona, and highlights the need for stronger academic–industry collaboration to advance this field. 🚀 🗣️ As Cristina Mayor-Ruiz notes, “Harnessing proximity-induced pharmacology offers unprecedented opportunities to modulate disease-driving proteins once deemed undruggable.” 🔝 The proposed Alliance seeks to pool expertise, infrastructure, and digital platforms across Europe (and beyond)  to train future leaders, boost translational research, and accelerate the development of next-generation proximity-based therapies. Read the full news here 🔗 https://lnkd.in/eSw9T3tN DOI: https://lnkd.in/eJBpRRuU #TargetedProteinDegradation #TPD #ProteinDegradation.

📌 Joan Guinovart y el IRB Barcelona · Revista SEBBM · Por Francesc Posas 👇 🗞️ Francesc Posas, director del IRB Barcelona, participa en este número especial de la Revista de la SEBBM para hablar sobre el legado de Joan Guinovart, plasmado en la creación del IRB Barcelona en 2005. Como director fundador del Instituto hasta 2018, Guinovart consolidó un entorno de excelencia que fomentó la investigación de alta calidad y la colaboración interdisciplinaria. 🤝 Su visión no solo dejó una marca en el IRB Barcelona, sino que su compromiso también se reflejó en su trabajo con la Sociedad Española de Bioquímica y Biología Molecular (SEBBM), donde fue presidente y socio de honor. Su liderazgo en diversas organizaciones científicas, como la Confederación de Sociedades Científicas de España (COSCE) y la International Union of Biochemistry and Molecular Biology (IUBMB), impulsó iniciativas cruciales para mejorar la investigación a nivel global. 🔬 La especialización de Guinovart en el metabolismo del glucógeno y su investigación sobre la diabetes y la enfermedad de Lafora aportaron conocimientos significativos al campo, dejando un impacto duradero en la comunidad científica. ✨ Más allá de sus logros profesionales, lo que realmente perdura es su humanidad, su generosidad y su capacidad para inspirar a aquellos que tuvieron el privilegio de trabajar a su lado. Su legado sigue vivo en el IRB Barcelona y en cada uno de nosotros. Para conocer más sobre su vida y contribuciones, te invitamos a leer el artículo completo aquí ➡️ https://shorturl.at/i782O #RevistaSEBBM #SEBBM #JoanGuinovart #IRBBarcelona

🔬 A breakthrough in tackling aggressive childhood cancer: A rare case of renal rhabdoid tumour—diagnosed in only about 12 children each year in Spain and with an extremely low survival rate—has opened new avenues for advanced cell therapies👇 💡 In a paediatric patient, a positive response to treatment allowed researchers to identify immune cells with strong anti-tumour activity in this cancer type. 💉 After chemotherapy and radiotherapy, the patient began immunotherapy with immune checkpoint inhibitors (ICI)—a strategy that boosts lymphocytes’ ability to detect and destroy tumour cells. 🩸 For over a year, scientists from the Centro Nacional de Análisis Genómico (CNAG), IRB Barcelona, and the Barcelona Children's Hospital Sant Joan de Déu monitored the patient’s immune system through blood samples. 🧬 Published in Annals of Oncology, the findings showcase how cutting-edge sequencing technologies can detect tumour-reactive immune cells in various tissues—especially in blood—paving the way for personalised immune therapies for rare and aggressive cancers. 📖 Read the full news here ➡️ https://bit.ly/44wayyq *** 📌 DOI: 10.1016/j.annonc.2025.05.530 Alexandra Avgustinova Inés Sentís Carreras Barcelona Children's Hospital Sant Joan de Déu Fundació de Recerca Sant Joan de Déu Centro Nacional de Análisis Genómico (CNAG) Omniscope ICERCA - Centres de Recerca de Catalunya Barcelona Institute of Science and Technology (BIST) SOMM Alliance Parc Científic de Barcelona #IRBScience #ChildhoodCancer #CancerResearch #Immunotherapy #PaediatricCancer #PediatricCancer #Research

🙌 #IRBBarcelona has contributed to a pioneering study that, for the first time, recorded the process of human embryo implantation in real time using a 3D model of the uterus. This advance holds great potential for improving IVF and deepening our understanding of infertility. Learn more in this post by Institute for Bioengineering of Catalonia (IBEC) 👇