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For large sparse table (many strata) CMHTest will occasionally throw a Error in solve.default(AVA) Not surprising when I inspect the sub-tables as there are lots of zeros. However, I am unable to catch it with a tryCatch wrapped around the CMHtest call. Are there any downsides to replacing the solve call with a call to MASS::ginv as I would normally do for a linear model? (aside from speed issues)