I don't really understand Why one should bother with the pluggable ports in something that's not a laptop. Even in 4.5L, shouldn't we just have "all the ports"?
If you already have a Framework laptop, it's nice to be able to reuse the extra cards that you might have lying around. "Leveraging the benefits of the Framework ecosystem," as a marketing person might say.
Also, this reminds me of "SkyReach Tiny":
https://store.nfc-systems.com/products/skyreach-4-tiny
an even smaller case, very versatile. No pluggable gimmicks though.