Sometimes a study can completely change the way we think about a disease. Until recently, HHT, a rare hereditary bleeding disorder, was thought to be a disease of nose bleeds. Our Digital CRO team, in partnership with Komodo Health's Healthcare Map, found something very different: the cost of treating HHT in the US is nearly a half billion dollars a year, driven almost entirely by anemia. How did an initial study on nosebleeds come to such a different conclusion? 1) The Komodo Healthmap database identified more than 24,000 patients diagnosed with HHT, many times more than any previously published study. 2) The 60% prevalence of anemia was higher than previously understood, and much more severe with nearly half those patients requiring hematologic support with blood transfusions and iron infusions. 3) The data revealed significant end-organ damage from bleeding in the brain, lungs, liver, and GI tract. We followed the consequences of anemia to the associated healthcare costs, which included a 40-fold increase in risk for liver transplant. Together with Diagonal Therapeutics, we changed the way investors, biotech and patient advocates think about HHT. We showed what is possible when you combine data at scale, Digital CRO expertise, and an openness to go where the data take you. Explore our full approach: https://lnkd.in/gee55xHh #slipstream #pharma #DigitalCRO
Slipstream IT
IT Services and IT Consulting
Blue Bell, Pennsylvania 15,941 followers
Life Sciences Accelerated. Expertise Delivered.
About us
Slipstream is a trusted technology partner exclusively serving the Life Sciences industry. Our global team brings deep domain expertise and pragmatic, end-to-end solutions that simplify complex challenges across the entire product lifecycle. We deliver with speed, compliance, and foresight— empowering clients to accelerate research, optimize time to market, and improve patient outcomes, ensuring technology keeps pace with their life-changing mission.
- Website
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http://www.slipstream-it.com
External link for Slipstream IT
- Industry
- IT Services and IT Consulting
- Company size
- 201-500 employees
- Headquarters
- Blue Bell, Pennsylvania
- Type
- Privately Held
- Founded
- 2020
- Specialties
- IT Outsourcing, Life Sciences IT, Veeva Implementation, and Veeva Support
Locations
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Primary
751 Arbor Way
Suite 100
Blue Bell, Pennsylvania 19422, US
Employees at Slipstream IT
Updates
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We're thrilled to announce a strategic investment from GreyLion with continued support from our trusted partner Denali Growth Partners. This investment validates what we've believed from day one: the life sciences industry needs technology partners who truly understand the complexity of bringing life-changing therapies to market. The funding will accelerate our growth across: → Cloud CRM Solutions → R&D and Commercial Services → AI Capabilities → Information Management We're energized to leverage this partnership to continue delivering the specialized expertise our clients depend on. #slipstream #expertisedelivered #lifesciences
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Slipstream and Komodo Health have a unique partnership to advance drug development. With more than 330 million patients in the Komodo HealthMap database, we were able to identify more than 24,000 patients in the U.S. with HHT, a rare hereditary bleeding disorder, creating the largest cohort ever studied. With longitudinal data, we found that the leading cost driver in HHT is anemia resulting from bleeding, not just in the nose but in the brain, lungs, liver and GI tract. In the liver alone this increased the risk of transplant 40-fold. Rare disease research requires big data. Maximizing its value requires expertise. The Komodo-Slipstream partnership has helped investors identify drug candidates with the greatest potential, has helped clinical development teams identify the best regulatory endpoints, and has armed patient advocacy organizations with data demonstrating the burden and unmet medical need in patients living with rare disease. Learn how we uncovered these insights: https://lnkd.in/ghGG8G_Q #DigitalCRO #slipstream #expertisedelivered
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Every life sciences leader knows that AI promises to transform how we discover, develop, and deliver therapies. But here's what many don't realize: without clean, organized data infrastructure, those AI investments become expensive experiments that rarely deliver ROI. The rush to adopt AI has exposed a critical gap. Companies are throwing resources at machine learning models while their data sits fragmented across legacy systems, riddled with quality issues, and locked in silos. The solution? Start with the foundation: - Establish proper data governance before AI adoption - Create unified data ecosystems that scale with growth - Build quality frameworks that ensure trustworthy insights - Design architecture that adapts to future innovations Our clients who invest in robust data infrastructure first see 3x better outcomes from their AI initiatives compared to those who try to bolt AI onto broken systems. Remember: AI is only as good as the data it learns from. #lifesciences #biotech #slipstream
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We shed light on a disease area far more serious than previously understood by the medical community. Using Komodo Health's 330M patient database and our Digital CRO offering, we challenged the myth that HHT is a disease of nose bleeds finding that patients with HHT suffer from severe and often untreated anemia that's costing the US healthcare system >$450M annually. Published in the American Journal of Hematology / Oncology®, and in collaboration with Diagonal Therapeutics, we have: - Helped the investment community understand the potential value of new HHT treatments - Helped the regulatory community define endpoints that truly reflect the seriousness of this disease - Armed patient advocacy organizations with data demonstrating the burden of this rare disease for both patients and the U.S. healthcare system Drug development is being redefined with the use of real-world data. Learn how Slipstream can help support your rare disease program 👉 https://lnkd.in/gnEzcujB #slipstream #pharma #DigitalCRO
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The real cost of a poorly planned CRM migration isn't the project itself. It's the months of cleanup work your team never budgeted for. When life sciences organizations skip proper planning, particularly during mergers or acquisitions, the fallout is predictable: - Data errors that create operational bottlenecks. - Fractured workflows that demoralize teams and hamper productivity. - Expensive remediation work that proper planning would have prevented. The path to successful CRM migration: 1 - Begin with comprehensive discovery. Map your existing systems, data relationships, and vulnerability points. 2 - Focus on strategic priorities. Resist migrating every customization and legacy feature. Keep only what drives your business forward. 3 - Execute in stages. Incremental rollouts minimize risk and help teams adapt more effectively. Strong migrations require coordination and transparent communication. Choose a partner who understands that. #lifesciences #biotech #slipstream
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Beyond proud of Tracy Mayne & team 👏 https://lnkd.in/exa4-wAN
One of the things I love about working in rare disease is the ability to define natural history and burden. Our article published in Hematology found that HHT, which had largely been defined by its most obvious sign, nosebleeds, is actually a complex disease of bleeding in multiple end organs resulting in anemia in most patients, and severe anemia requiring hematologic support in a quarter of patients. Bleeding in the liver increased risk of transplant 40-fold. HHT is a serious illness in need of new treatments. My colleagues at Diagonal Therapeutics are on that journey to make an incredible difference in patients’ lives! https://lnkd.in/g9Gd2CFY
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Commercial launches require orchestration across multiple teams and complex systems. Our PMO offering reflects this reality, supporting the full spectrum of life sciences operations: 👉 Clinical 👉 Medical 👉 Legal 👉 Facilities 👉 LIMS & SAP 👉 & more Learn more: https://lnkd.in/dtyfUMk #lifesciences #biotech #slipstream
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“Partnership” means something different to every organization. For us, we've distilled it down to 3 key principles: 1 - Expertise is freely shared. We foster communities where technology executives exchange strategies and tap into our worldwide network of industry leaders to accelerate their impact. 2 - The right challenge is addressed. Our teams provide deep technical expertise built over decades. We address our clients’ challenges strategically to create solutions, systems, and services that create results. 3 - Clients always come first. We deliver what we promise because we are committed to our clients’ success. Our global delivery centers ensure 100% near-shore white glove service. We are wherever our clients need to be. #lifesciences #biotech #slipstream
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It takes more than the right technology to deliver successful projects. A project’s success relies on a team with expertise in both technology and business strategy. 3 tips to make sure you achieve your target outcome: 1. Prioritize Transparency Challenges and change are part of every project. The key is to build transparency and trust in the team, giving people the ability to understand and quickly resolve issues together. Project issues are often trust issues. 2. Focus on Alignment The client and partner must be aligned on the scope and deliverables, while retaining the flexibility to identify and react to scope changes. Having a strong partnership allows for compromise while maintaining positive momentum. 3. Invest in the Process Having standard, repeatable project management methodologies and accelerators allow an organization to work with a higher level of efficacy. The investment of process, training, and repeatability is critical to success. Get expert support to drive your project forward: https://lnkd.in/gyuMD9Kb #lifesciences #biotech #slipstream