Sesame is an important oil crop grown in Ethiopia. It is grown in areas receiving annual rainfall between 625-1100mm and temperatures above 27°C. The major sesame growing regions in Ethiopia include Amhara, Tigray, Benishangul Gumuz, and Somali. Sesame requires hot conditions between 25-37°C to grow and yields are optimal with annual rainfall between 500-650mm. Diseases like bacterial blight and phyllody as well as insect pests such as webworm pose challenges to production. Proper agronomic practices including intercropping, fertilizer application, and control of weeds, pests and diseases can help maximize yields.