This document discusses barriers to the implementation of total quality management (TQM) in organizations. It analyzes the interaction among 12 identified TQM barriers using an interpretive structural modeling (ISM) approach. The research finds that the barriers can be categorized into two groups: those with high driving power and low dependency that require maximum attention, and those with high dependence and low driving power that are resultant effects. Adopting this ISM-based model of TQM barriers could help managers and practitioners better understand the barriers and prioritize addressing major barriers.