R can be used to analyze data and perform statistical analysis. Key functions include help() and ? to get information on functions, and objects() to view stored objects. Vectors can be created with c() and manipulated using arithmetic operators. Matrices are two-dimensional arrays that can be operated on using *, /, and t(). Larger datasets are typically read from external files using read.table() or read.delim(). Common distributions can be explored using functions like dnorm(), pnorm(), and rnorm(). Statistical analysis includes commands like cov() and cor() to measure covariance and correlation between variables.