David Kelly discusses upgrading an Oracle E-Business Suite to version 12.1.3. He recommends establishing a patch baseline and post go-live strategy by routinely patching applications for stability, supportability and access to new features. While major patches require time and effort, tools like Patch Wizard can help assess impact and target testing. Kelly also discusses Oracle versioning including releases, point releases, and release update packs. He provides recommendations for a 12.1.3 upgrade including applying the latest recommended patch collections to reduce issues and future patching needs.