This document provides an overview and introduction to LOINC (Logical Observation Identifiers Names and Codes). It discusses the origins and growth of LOINC as a universal standard for identifying laboratory and clinical observations. Key points include: LOINC was created in 1994 by Regenstrief Institute to facilitate information exchange; it has over 80,000 codes covering many clinical domains and is used internationally; and adoption has increased steadily with over 800 downloads per month and participation from many organizations globally and within the US.