This document provides instructions for refining denture setups after the trial denture try-in. It discusses refining setups for different types of occlusal schemes, including lingualized occlusion, monoplane occlusion, lingualized opposing monoplane, semi-anatomic, and anatomic. The key steps involve verifying occlusal contacts and relationships in centric, working, balancing, and protrusive positions and making adjustments as needed to achieve the desired occlusion.