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ANATOMY 
Cell 
Structure of cell 
M Humayun jamil 
7/4/2014 
It includes general review of cell. Structure of cell includes its three major parts and then each 
organelle is explained separately
Cell 
Cell is a structural and functional unit of body. Cells were first observed more than 300 years 
ago by the English scientist Robert Hooke. cell theory in 1838 and 1839 by two German 
biologists, Matthias Schleiden and Theodor Schwann. This theory states that all living organ-isms 
are composed of one or more cells and that the cell is the basic unit of structure for all 
organisms. 
Structure of cell 
Cell is basically devided into three parts 
1. Cell memberane 
2. Cytoplasm and organelles 
3. Nucleus 
Cell memberane 
The extremely thin cell (plasma) membrane is composed pri- marily of phospholipid and protein 
molecules. Its thickness ranges from 65 to 100 angstroms (Å); that is, it is less than a mil- lionth 
of an inch thick. The structure of the cell membrane is not fully understood, but most cytologists 
believe that it consists of a double layer of phospholipids in which larger globular proteins are 
embeded…………………read any book for further detail
Cytoplasm and Organelles 
Cytoplasm refers to the material located within the cell mem- brane but outside the nucleus. The 
material within the nucleus is frequently called the nucleoplasm. The term protoplasm is some-times 
used to refer to the cytoplasm and nucleoplasm collectively. When observed through an 
electron microscope , distinct cellular components called organelles can be seen in the highly 
structured cytoplasm. The matrix of the cytoplasm is a jel-lylike substance that is 80% to 90% 
water. The organelles and inorganic colloid substances (suspended particles) are dispersed 
throughout the cytoplasm. Colloid substances have similar ionic charges that space them 
uniformly. Metabolic activity occurs within the organelles of the cyto- plasm. Specific roles such 
as heat production, cellular mainte- nance, repair, storage, and protein synthesis are carried out 
within the organelles. 
Endoplasmic reticulum 
Often abbreviated ER, the endoplasmic reticulum (en″do- plaz′mik r˘e-tik′yu˘-lum) is widely 
distributed throughout the cyto- plasm as a complex network of interconnected membranes. 
Although the name sounds complicated, endoplasmic simply means “within the plasm” 
(cytoplasm of the cell) and reticulum means “network.” Between the interconnected mem - 
branes are minute spaces, or cisterna, that are connected at one end to the cell membranes. The 
tubules may also be connected to other organelles or to the outer nuclear envelope. The ER 
provides a pathway for transportation of substances within the cell and a storage area for 
synthesized molecules. There are two distinct varieties, either of which may predomi- nate in a 
given cell: 1.a rough, or granular, endoplasmic reticulum (rough ER), characterized by
numerous small granules called ribosomes that are attached to the outer surface of the 
membranous wall; and 2.a smooth endoplasmic reticulum (smooth ER) that lacks ribosomes. 
The membranous wall of rough ER provides a site for protein synthesis within ribosomes. 
Smooth ER manufactures certain lipid molecules. Also, enzymes within the smooth ER of liver 
cells inactivate or detoxify a variety of chemicals.
Ribosomes 
Ribosomes (ri′bo˘-somz) may occur as free particles suspended within the cytoplasm, or they 
may be attached to the membra- nous wall of the rough endoplasmic reticulum. Ribosomes are 
small, granular organelles composed of protein and RNA molecules. They synthesize protein 
molecules that may be used to build cell structures or to function as enzymes. Some of the 
proteins synthesized by ribosomes are secreted by the cell to be used elsewhere in the body.
Golgi Complex 
The Golgi (gol′je) complex (Golgi apparatus) consists of several tiny membranous sacs located 
near the nucleus . The Golgi complex is involved in the synthesis of carbohy- drates and cellular 
secretions. As large carbohydrate molecules are synthesized, they combine with proteins to form 
compounds called glycoproteins that accumulate in the channels of the Golgi complex. When a 
critical volume is reached, the vesicles break off from the complex and are carried to the cell 
membrane and released as a secretion. Once the vesicle has fused with the cell membrane, it 
ruptures to release its contents, thus com- pleting the process known as exocytosis. The Golgi 
complex is prominent in cells of certain secre- tory organs of the digestive system, including the 
pancreas and the salivary glands. Pancreatic cells, for example, produce diges- tive enzymes that 
are packaged in the Golgi complex and se- creted as droplets that flow into the pancreatic duct 
and are transported to the gastrointestinal (GI) tract.
Mitochondria 
Mitochondria (mi″to˘-kon′dre-a˘) are double-membraned saclike organelles. They are found in 
all cells in the body, with the ex- ception of mature red blood cells. The outer mitochondrial 
mem- brane is smooth, whereas the inner membrane is arranged in intricate folds called cristae 
(kris′te) . The cristae create a enormous surface area for chemical reactions. Mitochondria vary 
in size and shape. They can migrate through the cytoplasm and can reproduce themselves by 
budding or cleavage. They are often called the “powerhouses” of cells be- cause of their role in 
producing metabolic energy. Enzymes con- nected to the cristae control the chemical reactions 
that form ATP. Metabolically active cells, such as muscle cells, liver cells, and kidney cells, have 
a large number of mitochondria because of their high energy requirements.
Centrosome and Centrioles 
The centrosome (central body) is a nonmembranous spherical mass positioned near the nucleus. 
Within the centrosome, a pair of rodlike structures called centrioles (sen′tre-o¯lz) are 
positioned at right angles to each other. The wall of each centri- ole is composed of nine evenly 
spaced bundles, and each bundle contains three microtubules. Centrosomes are found only in 
those cells that can divide. During the mitotic (replication) process, the centrioles move away 
from each other and take positions on either side of the nu- cleus. They are then involved in the 
distribution of the chromo- somes during cellular reproduction. Mature muscle and nerve cells 
lack centrosomes, and thus cannot divide.
Vacuoles 
Vacuoles (vak′yoo-o¯lz) are membranous sacs of various sizes that usually function as storage 
chambers. They are formed when a portion of the cell membrane invaginates and pinches off 
during endocytosis. Vacuolation is initiated either by pinocytosis (pin″o˘- si-to′sis), in which 
cells take in minute droplets of liquid through the cell membrane, or by phagocytosis (fag″o˘-si-to′ 
sis), in which the cell membrane engulfs solid particles . Vacuoles may contain liquid or solid 
materials that were previously outside the cell.
Fibrils and Microtubules 
Both fibrils and microtubules are found throughout the cyto- plasm. The fibrils are minute 
rodlike structures, whereas the mi- crotubules are fine, threadlike tubular structures of varying 
length. Both provide the cell with support by forming a type of cytoskeleton. Specialized fibrils 
called myofilaments are particularly abundant in muscle cells, where they aid in the con-traction 
of these cells. Microtubules are also involved in the transportation of macromolecules 
throughout the cytoplasm. They are especially abundant in the cells of endocrine organs, where 
they aid the movement of hormones to be secreted into the blood. Microtubules in certain cells 
provide flexible support for cilia and flagella.
Cell Nucleus 
The spherical nucleus is usually located near the center of the cell . It is the largest structure of 
the cell and contains the genetic material that determines cellular structure and con- trols 
cellular activity. Most cells contain a single nucleus. Certain cells, however, such as skeletal 
muscle cells, are multinucleated. The long skele- tal muscle fibers contain so much cytoplasm 
that several govern- ing centers are necessary. Other cells, such as mature red blood cells, lack 
nuclei. These cells are limited to certain types of chemical activities and are not capable of cell 
division. The nucleus is enclosed by a bilayered nuclear membrane (nuclear envelope) . The 
narrow space between the inner and outer layers of the nuclear membrane is called the nu-cleolemma 
cisterna (sis-ter′na). Minute nuclear pores are lo- cated along the nuclear membrane. 
These openings are lined with proteins that act as selective gates, allowing certain mole- cules, 
such as proteins, RNA, and protein-RNA complexes, to move between the nucleoplasm and the 
cytoplasm. 
Two important structures within the nucleoplasm of the nucleus determine what a cell will look 
like and what functions it will perform: 1. Nucleoli. Nucleoli (noo-kle′o˘-li) are small, 
nonmembra- nous spherical bodies composed largely of protein and RNA. It is thought that they 
function in the production of ribosomes. As ribosomes are formed, they migrate through the 
nuclear membrane into the cytoplasm. 2. Chromatin. Chromatin (kro′ma˘-tin) is a coiled,
thread- like mass. It is the genetic material of the cell and consists principally of protein and 
DNA molecules. When a cell begins to divide, the chromatin shortens and thickens into rod-shaped 
structures called chromosomes (kro′mo˘-so¯mz) . Each chromosome carries thousands 
In case of any mistake please 
inform me at my address 
Humayunjamil4@gmail.com 
Thankx 
of genes that determine the structure and function of a cell.

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2.cell structure

  • 1. ANATOMY Cell Structure of cell M Humayun jamil 7/4/2014 It includes general review of cell. Structure of cell includes its three major parts and then each organelle is explained separately
  • 2. Cell Cell is a structural and functional unit of body. Cells were first observed more than 300 years ago by the English scientist Robert Hooke. cell theory in 1838 and 1839 by two German biologists, Matthias Schleiden and Theodor Schwann. This theory states that all living organ-isms are composed of one or more cells and that the cell is the basic unit of structure for all organisms. Structure of cell Cell is basically devided into three parts 1. Cell memberane 2. Cytoplasm and organelles 3. Nucleus Cell memberane The extremely thin cell (plasma) membrane is composed pri- marily of phospholipid and protein molecules. Its thickness ranges from 65 to 100 angstroms (Å); that is, it is less than a mil- lionth of an inch thick. The structure of the cell membrane is not fully understood, but most cytologists believe that it consists of a double layer of phospholipids in which larger globular proteins are embeded…………………read any book for further detail
  • 3. Cytoplasm and Organelles Cytoplasm refers to the material located within the cell mem- brane but outside the nucleus. The material within the nucleus is frequently called the nucleoplasm. The term protoplasm is some-times used to refer to the cytoplasm and nucleoplasm collectively. When observed through an electron microscope , distinct cellular components called organelles can be seen in the highly structured cytoplasm. The matrix of the cytoplasm is a jel-lylike substance that is 80% to 90% water. The organelles and inorganic colloid substances (suspended particles) are dispersed throughout the cytoplasm. Colloid substances have similar ionic charges that space them uniformly. Metabolic activity occurs within the organelles of the cyto- plasm. Specific roles such as heat production, cellular mainte- nance, repair, storage, and protein synthesis are carried out within the organelles. Endoplasmic reticulum Often abbreviated ER, the endoplasmic reticulum (en″do- plaz′mik r˘e-tik′yu˘-lum) is widely distributed throughout the cyto- plasm as a complex network of interconnected membranes. Although the name sounds complicated, endoplasmic simply means “within the plasm” (cytoplasm of the cell) and reticulum means “network.” Between the interconnected mem - branes are minute spaces, or cisterna, that are connected at one end to the cell membranes. The tubules may also be connected to other organelles or to the outer nuclear envelope. The ER provides a pathway for transportation of substances within the cell and a storage area for synthesized molecules. There are two distinct varieties, either of which may predomi- nate in a given cell: 1.a rough, or granular, endoplasmic reticulum (rough ER), characterized by
  • 4. numerous small granules called ribosomes that are attached to the outer surface of the membranous wall; and 2.a smooth endoplasmic reticulum (smooth ER) that lacks ribosomes. The membranous wall of rough ER provides a site for protein synthesis within ribosomes. Smooth ER manufactures certain lipid molecules. Also, enzymes within the smooth ER of liver cells inactivate or detoxify a variety of chemicals.
  • 5. Ribosomes Ribosomes (ri′bo˘-somz) may occur as free particles suspended within the cytoplasm, or they may be attached to the membra- nous wall of the rough endoplasmic reticulum. Ribosomes are small, granular organelles composed of protein and RNA molecules. They synthesize protein molecules that may be used to build cell structures or to function as enzymes. Some of the proteins synthesized by ribosomes are secreted by the cell to be used elsewhere in the body.
  • 6. Golgi Complex The Golgi (gol′je) complex (Golgi apparatus) consists of several tiny membranous sacs located near the nucleus . The Golgi complex is involved in the synthesis of carbohy- drates and cellular secretions. As large carbohydrate molecules are synthesized, they combine with proteins to form compounds called glycoproteins that accumulate in the channels of the Golgi complex. When a critical volume is reached, the vesicles break off from the complex and are carried to the cell membrane and released as a secretion. Once the vesicle has fused with the cell membrane, it ruptures to release its contents, thus com- pleting the process known as exocytosis. The Golgi complex is prominent in cells of certain secre- tory organs of the digestive system, including the pancreas and the salivary glands. Pancreatic cells, for example, produce diges- tive enzymes that are packaged in the Golgi complex and se- creted as droplets that flow into the pancreatic duct and are transported to the gastrointestinal (GI) tract.
  • 7. Mitochondria Mitochondria (mi″to˘-kon′dre-a˘) are double-membraned saclike organelles. They are found in all cells in the body, with the ex- ception of mature red blood cells. The outer mitochondrial mem- brane is smooth, whereas the inner membrane is arranged in intricate folds called cristae (kris′te) . The cristae create a enormous surface area for chemical reactions. Mitochondria vary in size and shape. They can migrate through the cytoplasm and can reproduce themselves by budding or cleavage. They are often called the “powerhouses” of cells be- cause of their role in producing metabolic energy. Enzymes con- nected to the cristae control the chemical reactions that form ATP. Metabolically active cells, such as muscle cells, liver cells, and kidney cells, have a large number of mitochondria because of their high energy requirements.
  • 8. Centrosome and Centrioles The centrosome (central body) is a nonmembranous spherical mass positioned near the nucleus. Within the centrosome, a pair of rodlike structures called centrioles (sen′tre-o¯lz) are positioned at right angles to each other. The wall of each centri- ole is composed of nine evenly spaced bundles, and each bundle contains three microtubules. Centrosomes are found only in those cells that can divide. During the mitotic (replication) process, the centrioles move away from each other and take positions on either side of the nu- cleus. They are then involved in the distribution of the chromo- somes during cellular reproduction. Mature muscle and nerve cells lack centrosomes, and thus cannot divide.
  • 9. Vacuoles Vacuoles (vak′yoo-o¯lz) are membranous sacs of various sizes that usually function as storage chambers. They are formed when a portion of the cell membrane invaginates and pinches off during endocytosis. Vacuolation is initiated either by pinocytosis (pin″o˘- si-to′sis), in which cells take in minute droplets of liquid through the cell membrane, or by phagocytosis (fag″o˘-si-to′ sis), in which the cell membrane engulfs solid particles . Vacuoles may contain liquid or solid materials that were previously outside the cell.
  • 10. Fibrils and Microtubules Both fibrils and microtubules are found throughout the cyto- plasm. The fibrils are minute rodlike structures, whereas the mi- crotubules are fine, threadlike tubular structures of varying length. Both provide the cell with support by forming a type of cytoskeleton. Specialized fibrils called myofilaments are particularly abundant in muscle cells, where they aid in the con-traction of these cells. Microtubules are also involved in the transportation of macromolecules throughout the cytoplasm. They are especially abundant in the cells of endocrine organs, where they aid the movement of hormones to be secreted into the blood. Microtubules in certain cells provide flexible support for cilia and flagella.
  • 11. Cell Nucleus The spherical nucleus is usually located near the center of the cell . It is the largest structure of the cell and contains the genetic material that determines cellular structure and con- trols cellular activity. Most cells contain a single nucleus. Certain cells, however, such as skeletal muscle cells, are multinucleated. The long skele- tal muscle fibers contain so much cytoplasm that several govern- ing centers are necessary. Other cells, such as mature red blood cells, lack nuclei. These cells are limited to certain types of chemical activities and are not capable of cell division. The nucleus is enclosed by a bilayered nuclear membrane (nuclear envelope) . The narrow space between the inner and outer layers of the nuclear membrane is called the nu-cleolemma cisterna (sis-ter′na). Minute nuclear pores are lo- cated along the nuclear membrane. These openings are lined with proteins that act as selective gates, allowing certain mole- cules, such as proteins, RNA, and protein-RNA complexes, to move between the nucleoplasm and the cytoplasm. Two important structures within the nucleoplasm of the nucleus determine what a cell will look like and what functions it will perform: 1. Nucleoli. Nucleoli (noo-kle′o˘-li) are small, nonmembra- nous spherical bodies composed largely of protein and RNA. It is thought that they function in the production of ribosomes. As ribosomes are formed, they migrate through the nuclear membrane into the cytoplasm. 2. Chromatin. Chromatin (kro′ma˘-tin) is a coiled,
  • 12. thread- like mass. It is the genetic material of the cell and consists principally of protein and DNA molecules. When a cell begins to divide, the chromatin shortens and thickens into rod-shaped structures called chromosomes (kro′mo˘-so¯mz) . Each chromosome carries thousands In case of any mistake please inform me at my address Humayunjamil4@gmail.com Thankx of genes that determine the structure and function of a cell.