The 4th International Conference on Soft Computing, Control, and Mathematics (SCM 2021) took place on December 11-12, 2021, in Chennai, India, focusing on the latest developments in soft computing, mathematics, and control. Researchers and practitioners from various fields were invited to submit original papers by November 20, 2021, with selected works to be published in reputable journals. The conference aimed to foster knowledge sharing and address the challenges within these scientific disciplines.