The 5th International Conference on Machine Learning & Applications (CMLA 2023) is scheduled for June 17-18, 2023, in Sydney, Australia, focusing on sharing knowledge in machine learning theory, methodology, and applications. Researchers and practitioners can submit original papers by May 27, 2023, which will be published in the computer science conference proceedings and selected papers may appear in special journal issues. Key topics include machine learning algorithms, deep learning, computer vision, and data mining.