This document provides guidance on hazardous materials response. It outlines the key incident priorities of life safety, incident stabilization, and property conservation. It then describes the basic steps to hazardous materials incident management, including isolation, notification, identification, protection, spill control, leak control, fire control, and recovery/termination. The document also discusses defensive and offensive response operations and the different levels of personal protective equipment. It emphasizes that initial responders should focus on life safety through isolation, notification, and protection at the operations level.