An open trial was conducted to evaluate the effectiveness of a brief, school nurse-delivered cognitive behavioral therapy (CALM) intervention for reducing anxiety in children. Nine school nurses delivered the six-session CALM intervention to 11 anxious children ages 5-11. Measures from children, parents, teachers, and evaluators showed statistically significant reductions in parent- and child-reported anxiety and somatic symptoms, as well as improvements in clinical severity ratings and functioning after the intervention. The majority of nurses, parents, and children perceived the intervention as helpful. However, the open trial design without a comparison group limits conclusions about the intervention's efficacy.