This document discusses advanced polymorphic techniques used by viruses to evade antivirus detection. It begins by explaining how early viruses used simple encryption and polymorphism to mutate their code on replication. As antiviruses adapted by scanning decrypted code, viruses evolved to use metamorphic techniques that thoroughly change the viral code even after decryption. The document then analyzes the METAPHOR virus as the most advanced metamorphic virus today, using techniques like dead code insertion and register shuffling to mutate its code without altering functionality.