After Effects is a digital motion graphics and visual effects software used in post-production. It is used to create 2D and 2.5D animation, visual effects, and image adjustment. The main panels include the composition window for previewing, the project window for storing assets, and the timeline for layering elements. Users can import files, set composition duration, place layers, and use time controls like looping. Individual panels can be zoomed by clicking the zoom icon in the top right corner.