An intercalating agent 1. Inserts between base pairs of the two str.pdf
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An intercalating agent inserts between DNA base pairs, causing double-stranded and single-stranded lesions, and commonly leads to transversion mutations. A chelating agent consists of a ligand forming multiple bonds with a central atom, typically involving organic compounds called chelants or chelators. Both concepts relate to interactions with nucleic acids and metal ions in biochemical contexts.
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An intercalating agent 1. Inserts between base pairs of the two str.pdf
- 1. An intercalating agent: 1. Inserts between base pairs of the two strands of DNA 2. Makes double- stranded lesions in the DNA 3. Inserts between adjacent base pairs on a single strand of DNA 4. Commonly causes transversion mutations 5. Makes single-stranded lesions in the DNA Solution Chelating agent involves the formation or presence of two or more separate coordinate bonds between a polydentate (multiple bonded) ligand and a single central atom. Usually these ligands are organic compounds, and are called chelants, chelators, chelating agents, or sequestering agents.