This study analyzed transformer loadings and failure rates in the Onitsha electricity distribution network in Nigeria from 2011-2015. Electrical data from the network was simulated using ETAP software to determine transformer loadings, while questionnaires assessed failure rates. The findings showed an average transformer failure rate of 11.7% during the study period, higher than rates in developed countries. Major causes of failure included insulation issues (24.2%), overloading (22.5%), and inadequate maintenance (16.4%). The Army Barracks substation had the highest failure rate of 23.8%. The study recommends installing more transformers, using high quality transformers, balancing loads, and improving maintenance to increase reliability.