This document provides information about the anatomy, clinical presentation, diagnosis, and treatment of appendicitis. It describes the appendix's location, blood supply, and relations to other structures in the abdomen. Common symptoms of appendicitis include pain, vomiting, fever, and tenderness in the right lower quadrant. Diagnosis is based on physical exam findings at McBurney's point. Treatment is an appendectomy, which can be performed via open or laparoscopic surgery using various incision types depending on the appendix's position and degree of inflammation. Complications may include peritonitis if not treated promptly.