The PerkinElmer AxION 2 TOF Mass Spectrometer is a time-of-flight mass spectrometer featuring a mass range of 18-12,000 m/z, mass measurement accuracy of ≤2 ppm at 1,000 m/z, and resolution of ≥12,000 FWHM at 922 m/z. It has high sensitivity for ESI with a S/N≥40:1 for 1 pg/μl reserpine and S/N≥50:1 for 2 pg/μl p-nitrophenol. The instrument operates between 16-26°C and has ion sources including Ultraspray ESI and Field-Free APCI.