basic introductionary lecture on endocrinology and thyroid
Download as PPTX, PDF12 likes1,800 views
This document provides an introductionary lecture on endocrinology and the thyroid. It defines hormones and lists the major endocrine glands and their hormones, including the pituitary gland, thyroid gland, parathyroid gland, pancreas, adrenal glands, gonads, and hypothalamus. It then describes the mechanisms of action of hormones at cell membrane receptors, cytoplasmic receptors, and nuclear receptors. The document concludes with an overview of the thyroid, including its anatomy, histology, physiology, biochemistry, diagnosis, and surgical treatment.
basic introductionary lecture on endocrinology and thyroid
- 2. Endocrinology thyroid anti-thyroiddrugs Dr. Pranesh Vijay Pawaskar Resident Dept. of Pharmacology L.T.M.M.C. Sion, Mumbai 22 Date – 14/12/2016
- 3. endocrinology Hormone (Greek hormaein—to stir up) = is a substance of intense biological activity that is produced by specific cells in the body and is transported through circulation to act on its target cells.
- 5. Glands andhormones 1. Pituitary = (a) Anterior = Growth hormone (GH), Prolactin (Prl), Adrenocorticotropic hormone (ACTH, Corticotropin), Thyroid stimulating hormone (TSH, Thyrotropin), Gonadotropins—Follicle stimulating hormone (FSH) and Luteinizing hormone (LH). (b) Posterior = Oxytocin, Antidiuretic hormone (ADH, Vasopressin).
- 7. Glands andhormones Thyroid = Thyroxine (T4), Triiodothyronine (T3), Calcitonin
- 9. Glands andhormones Pancreas = (Islets of Langerhans) Insulin, Glucagon.
- 10. Glands andhormones Adrenals = (a) Cortex = Glucocorticoids (hydrocortisone) Mineralocorticoids (aldosterone) Sex steroids (dehydroepiandrosterone) (b) Medulla = Adrenaline, Noradrenaline
- 11. Glands andhormones Gonads = Androgens (testosterone) Estrogens (estradiol) Progestins (progesterone)
- 12. Glands andhormones Hypothalamus = Releasing hormones
- 13. mechanism At cell membrane receptors 1) Through cAMP = Adrenaline, Glucagone, TSH, LH, FSH, PTH, Calcitonin, ACTH. 2) Through IP3, DAG pathway = Vasopressin, Oxytocin. 3) Transmembrane Tyr.Kinase = Insulin, GH, Prolactin.
- 14. Mechanism at cytoplasmic receptors • Penetrating cell membrane = • Steroidal hormones : Glucocorticoids, Mineralocorticoid, Androgens, Estrogens, Progestins, Calcitriol.
- 15. Mechanism at nuclear receptor • Hormone penetrates the nucleus = Thyroid hormones, Thyroxine, Triiodothyronine.
- 16. thyroid
- 17. anatomy
- 18. histology
- 19. physiology
- 21. biochemistry
- 22. biochemistry
- 25. Synthesis , storage, secretion
- 26. diagnosis
- 38. surgery
- 39. Thank you