Capnography is a non-invasive method to measure exhaled carbon dioxide (CO2) levels, playing a critical role in assessing ventilation and detecting respiratory issues. It differentiates between oxygenation and ventilation, provides insights into pulmonary circulation and metabolic activity, and can indicate conditions like hypoventilation or hyperventilation. Barriers to its use include knowledge gaps and high costs, but its advantages in patient monitoring make it a vital tool in critical care.