Bioassay a presentation on the topic of Biostatistics
- 2. • A bioassay is an analytical method to determine the concentration or potency of a substance by its effect on living animals or plants (in vivo), or on living cells or tissues(in vitro). Main Pharmacological effect of a drug. Compared with Pharmacological effect of standard drug. Potency ratios are compared quantitively. WHAT IS BIOASSAY?
- 3. COMPONENTS OF A BIOASSAY • The subject is usually an animal, a human tissue, or a bacteria culture. • The agent is usually a drug, a chemical. • The response is usually a change in a particular characteristic or even the death of a subject, responses can be binary or measured on continuous scale.
- 4. To measure the pharmacological activity of new chemically undefined substance. To measure drug toxicity and unwanted effects. To measure the concentration of drug and other active substances in the blood or other body fluids. To predict some type of therapeutic potential, either direct or indirect or by analogy, of test compounds. USE OF BIOASSAY:
- 5. Bioassay Direct Indirect Quantal Quantitative Slope Ratio Model Parallel Line Model CLASSIFICATIONS:
- 6. https://en.wikipedia.org/wiki/Bioassay https://www.sciencedirect.com/topics/nursing-and-health-professions/bioassay https://www.ncbi.nlm.nih.gov/books/NBK100913/table/highcontent.T.examples_ of_bioassays/ REFERENCES:
- 7. THANK YOU!