Bioinformatics in pandemic
- 1. Seminar on BIOINFORMATICS IN PANDEMIC Guided by: Dr. Jamuna K S Lecturer, Department of Biotechnology Sahyadri Science College Shimoga. SAHYADRI SCIENCE COLLEGE Presented by: Puneeth V G I M.Sc Biotechnology Sahyadri Science College Shimoga.
- 3. in silico molecular biology
- 4. “disease occurring worldwide, or over a very wide area crossing international boundaries and usually affecting a large number of people”. Bulletin of the World Health Organization, doi: 10.2471/BLT.11.088815
- 5. Vaccine Drug Both of them takes longer path
- 6. Vaccine Drug Bioinformatics cut shorts this longer path
- 7. Identification of drug / vaccine target plays more important role than identifying drug / vaccine itself
- 8. Genome/Proteome Sequencing plays a critical role
- 10. Movie – villain = Hero Host genome or proteome Pathogen genome or proteome Drug or vaccine target - = Reductive Genomics
- 11. Host genome/proteome Pathogen genome/proteome Identifying overlapping genes/proteins with similarity at sequence level, pathway level and flux level Annotation of unique and unknown sequences, their sub-cellular localization and their availability for drug.
- 12. Host genome/proteome Pathogen genome/proteome Ultimately, few proteins remain that may be treated as vaccine or drug targets
- 13. Bioinformatics can aid in identification of drug or vaccine targets at the earliest with least resources and economy. “ ”
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