Biosensing using nanomaterials 1st Edition A. Merkoci
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- 5. Biosensing using nanomaterials 1st Edition A. Merkoci Digital Instant Download Author(s): A. Merkoci ISBN(s): 9780470447727, 0470447729 Edition: 1 File Details: PDF, 61.96 MB Year: 2009 Language: english
- 8. WILEY SERIES IN NANOSCIENCE AND NANOTECHNOLOGY Arben Merkoçi,Series Editor BIOSENSING USING NANOMATERIALS / Arben Merkoçi,Editor nanoscience-cp.qxd 1/28/2009 12:37 PM Page 1
- 9. BIOSENSING USING NANOMATERIALS Edited by Arben Merkoçi
- 10. Copyright # 2009 by John Wiley & Sons, Inc. All rights reserved. Published by John Wiley & Sons, Inc., Hoboken, New Jersey. Published simultaneously in Canada. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning, or otherwise, except as permitted under Section 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, (978) 750-8400, fax (978) 750-4470, or on the web at www.copyright.com. Requests to the Publisher for permission should be addressed to the Permissions Department, John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, (201) 748-6011, fax (201) 748-6008, or online at http://www.wiley.com/go/permission. Limit of Liability/Disclaimer of Warranty: While the publisher and author have used their best efforts in preparing this book, they make no representations or warranties with respect to the accuracy or comple- teness of the contents of this book and specifically disclaim any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives or written sales materials. The advice and strategies contained herein may not be suitable for your situation. You should consult with a professional where appropriate. Neither the publishernor author shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, conse- quential, or other damages. For general information on our other products and services or for technical support, please contact our Customer Care Department within the United States at (800) 762-2974, outside the United States at (317) 572-3993 or fax (317) 572-4002. Wiley also publishes its books in a variety of electronic formats. Some content mat appears in print may not be available in electronic formats. For more information about Wiley products, visit our web site at www. wiley.com. Library of Congress Cataioging-in-Publication Data: Merkoçi, A. (Arben) Biosensing using nanomaterials / Arben Merkoçi. p. cm. - - (Wiley series in nanoscience and nanotechnology) Includes index. ISBN 978-0-470-18309-0 (cloth) 1. Biosensors. 2. Nanostructured materials. I. Title. R857.B54M47 2009 610.28’4- -dc22 2009005618 Printed in the United States of America 10 9 8 7 6 5 4 3 2 1
- 11. CONTENTS CONTRIBUTORS xi SERIES PREFACE xv PREFACE xvii PART I CARBON NANOTUBES 1 1. Carbon Nanotube–Based Sensors and Biosensors 3 Richard G. Compton, Gregory G. Wildgoose, and Elicia L. S. Wong 1.1. Introduction to the Structure of Carbon Nanotubes 3 1.2. Electroanalysis Using CNT-Modified Electrodes 7 1.3. Advantageous Application of CNTs in Sensors: pH Sensing 13 1.4. Carbon Nanotube–Based Biosensors 18 1.5. Using CNTs in Biosensor Production for Medical Diagnostics and Environmental Applications 25 References 30 2. Isotropic Display of Biomolecules on CNT-Arrayed Nanostructures 39 Mark R. Contarino, Gary Withey, and Irwin Chaiken 2.1. Introduction: CNT Arrays for Biosensing 40 2.2. Functionalization of CNTs: Controlling Display Through Covalent Attachment 41 2.3. Self-Assembling Interfaces: Anchor-Probe Approach 49 2.4. Molecular Wiring of Redox Enzymes 53 2.5. Multiplexing Biomolecules on Nanoscale CNT Arrays 54 2.6. Conclusions 59 References 60 3. Interaction of DNA with CNTs: Properties and Prospects for Electronic Sequencing 67 Sheng Meng and Efthimios Kaxiras 3.1. Introduction 68 3.2. Structural Properties of Combined DNA–CNT Systems 70 3.3. Electronic Structure 79 v
- 12. 3.4. Optical Properties 85 3.5. Biosensing and Sequencing of DNA Using CNTs 88 3.6. Summary 92 References 93 PART II NANOPARTICLES 97 4. Improved Electrochemistry of Biomolecules Using Nanomaterials 99 Jianxiu Wang, Andrew J. Wain, Xu Zhu, and Feimeng Zhou 4.1. Introduction 100 4.2. CNT-Based Electrochemical Biosensors 100 4.3. Nanoparticle-Based Electrochemical Biosensors 110 4.4. Quantum Dot–Based Electrochemical Biosensors 122 4.5. Conclusions and Outlook 123 References 125 5. The Metal Nanoparticle Plasmon Band as a Powerful Tool for Chemo- and Biosensing 137 Audrey Moores and Pascal Le Floch 5.1. Introduction 138 5.2. The SPB: An Optical Property of Metal NPs 143 5.3. Plasmon Band Variation Upon Aggregation of Nanoparticles 154 5.4. Plasmon Band Variation on the Environment or Ligand Alteration 164 5.5. Metal Nanoparticles as Labels 167 5.6. Conclusions 169 References 170 6. Gold Nanoparticles: A Versatile Label for Affinity Electrochemical Biosensors 177 Adriano Ambrosi, Alfredo de la Escosura-Muñiz, Maria Teresa Castañeda, and Arben Merkoçi 6.1. Introduction 178 6.2. Synthesis of AuNPs 179 6.3. Characterization of AuNPs 179 6.4. AuNPs as Detecting Labels for Affinity Biosensors 181 6.5. Conclusions 191 References 192 7. Quantum Dots for the Development of Optical Biosensors Based on Fluorescence 199 W. Russ Algar and Ulrich J. Krull 7.1. Introduction 200 vi CONTENTS
- 13. 7.2. Quantum Dots 205 7.3. Basic Photophysics and Quantum Confinement 207 7.4. Quantum Dot Surface Chemistry and Bioconjugation 212 7.5. Bioanalytical Applications of Quantum Dots as Fluorescent Labels 225 7.6. Fluorescence Resonance Energy Transfer and Quantum Dot Biosensing 232 7.7. Summary 238 References 239 8. Nanoparticle-Based Delivery and Biosensing Systems: An Example 247 Almudena Muñoz Javier, Pablo del Pino, Stefan Kudera, and Wolfgang J. Parak 8.1. Introduction 247 8.2. Functional Colloidal Nanoparticles 250 8.3. Polyelectrolyte Capsules as a Functional Carrier System 256 8.4. Uptake of Capsules by Cells 259 8.5. Delivery and Sensing with Polyelectrolyte Capsules 262 8.6. Conclusions 270 References 270 9. Luminescent Quantum Dot FRET-Based Probes in Cellular and Biological Assays 275 Lifang Shi, Nitsa Rosenzweig, and Zeev Rosenzweig 9.1. Introduction 275 9.2. Luminescent Quantum Dots 276 9.3. Fluorescence Resonance Energy Transfer 278 9.4. Quantum Dot FRET-Based Protease Probes 280 9.5. Summary and Conclusions 283 References 284 10. Quantum Dot–Polymer Bead Composites for Biological Sensing Applications 291 Jonathan M. Behrendt and Andrew J. Sutherland 10.1. Introduction 291 10.2. Quantum Dot–Composite Construction 293 10.3. Applications of QD Composites 307 10.4. Future Directions 325 References 327 11. Quantum Dot Applications in Biomolecule Assays 333 Ying Xu, Pingang He, and Yuzhi Fang 11.1. Introduction to QDs and Their Applications 333 11.2. Preparation of QDs for Conjugation with Biomolecules and Cells 337 CONTENTS vii
- 14. 11.3. Special Optoelectronic Properties in the Bioemployment of QDs 340 11.4. Employment of QDs as Biosensing Indicators 344 References 349 12. Nanoparticles and Inductively Coupled Plasma Mass Spectroscopy–Based Biosensing 355 Arben Merkoçi, Roza Allabashi, and Alfredo de la Escosura-Muñiz 12.1. ICP-MS and Application Possibilities 355 12.2. Detection of Metal Ions 360 12.3. Detection of Nanoparticles 361 12.4. Analysis of Metal-Containing Biomolecules 363 12.5. Bioanalysis Based on Labeling with Metal Nanoparticles 364 12.6. Conclusions 372 References 373 PART III NANOSTRUCTURED SURFACES 377 13. Integration Between Template-Based Nanostructured Surfaces and Biosensors 379 Walter Vastarella, Jan Maly, Mihaela Ilie, and Roberto Pilloton 13.1. Introduction 380 13.2. Nanosphere Lithography 380 13.3. Nanoelectrodes Ensemble for Biosensing Devices 390 13.4. Concluding Remarks 406 References 407 14. Nanostructured Affinity Surfaces for MALDI-TOF-MS–Based Protein Profiling and Biomarker Discovery 421 R. M. Vallant, M. Rainer, M. Najam-Ul-Haq, R. Bakry, C. Petter, N. Heigl, G. K. Bonn, and C. W. Huck 14.1. Proteomics and Biomarkers 421 14.2. MALDI in Theory and Practice 422 14.3. Carbon Nanomaterials 429 14.4. Near-Infrared Diffuse Reflection Spectroscopy of Carbon Nanomaterials 448 References 451 PART IV NANOPORES 457 15. Biosensing with Nanopores 459 Ivan Vlassiouk and Sergei Smirnov 15.1. Nanoporous Materials in Sensing 459 viii CONTENTS
- 15. 15.2. Nanochannel and Nanopore Fabrication 460 15.3. Surface Modification Chemistry 469 15.4. Nonelectrical Nanoporous Biosensors 472 15.5. Electrical Nanoporous Biosensors 474 15.6. Summary 486 References 486 INDEX 491 CONTENTS ix
- 16. CONTRIBUTORS W. Russ Algar, Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, Ontario, Canada Roza Allabashi, University of Natural Resources and Applied Life Sciences, Vienna, Austria Adriano Ambrosi, Nanobioelectronics and Biosensors Group, Institut Catal a de Nanotecnologia, Barcelona, Spain R. Bakry, Institute of Analytical Chemistry and Radiochemistry, Leopold-Franzens University, Innsbruck, Austria Jonathan M. Behrendt, Department of Chemical Engineering and Applied Chem- istry, Aston University, Birmingham, United Kingdom G.K.Bonn,InstituteofAnalyticalChemistryandRadiochemistry,Leopold-Franzens University, Innsbruck, Austria Maria Teresa Castañeda, Nanobioelectronics and Biosensors Group, Institut Catal a de Nanotecnologia, Barcelona, Spain, and Grup de Sensors i Biosensors, Departa- mento de Qu ımica, Universitat Autònoma de Barcelona, Bellaterra, Catalonia, Spain; on leave from Departamento de Ciencias B asicas, Universidad Autónoma Metropolitana-Azcapotzalco, M exico D.F., M exico Irwin Chaiken, Department of Biochemistry and Molecular Biology, Drexel Uni- versity College of Medicine, Philadelphia, Pennsylvania Richard G. Compton, Physical and Theoretical Chemistry Laboratory, Oxford University, Oxford, United Kingdom Mark R. Contarino, School of Biomedical Engineering, Science and Health Systems, Drexel University, and Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, Pennsylvania Alfredo de la Escosura-Muñiz, Nanobioelectronics and Biosensors Group, Institut Catal a de Nanotecnologia, Barcelona, Spain, and Instituto de Nanociencia de Aragón, Universidad de Zaragoza, Zaragoza, Spain Pablo del Pino, Fachbereich Physik, Philipps Universit€ at Marburg, Marburg, Germany Yuzhi Fang, Department of Chemistry, East China Normal University, Shanghai, China xi
- 17. Pingang He, Department of Chemistry, East China Normal University, Shanghai, China N. Heigl, Institute of Analytical Chemistry and Radiochemistry, Leopold-Franzens University, Innsbruck, Austria C. W. Huck, Institute of Analytical Chemistry and Radiochemistry, Leopold- Franzens University, Innsbruck, Austria MihaelaIlie,DepartmentofAppliedElectronicsandInformationEngineering,LAPI, Universitatea Politehnica Bucureşti, Bucharest, Romania Efthimios Kaxiras, Department of Physics and School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts Ulrich J. Krull, Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, Ontario, Canada Stefan Kudera, Department of New Materials and Biosystems, Max Planck Institute for Metals Research, and Department of Biophysical Chemistry, University of Heidelberg, Stuttgart, Germany Pascal Le Floch, H et ero el ements et Coordination, Ecole Polytechnique, Palaiseau, France JanMaly,DepartmentofBiology,University ofJ.E. Purkyne,Usti nadLabem,Czech Republic Sheng Meng, Department of Physics and School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts Arben Merkoçi, ICREA and Nanobioelectronics and Biosensors Group, Institut Catal a de Nanotecnologia, Barcelona, Spain Audrey Moores, Department of Chemistry, McGill University, Montreal, Quebec, Canada Almudena Muñoz Javier, Fachbereich Physik, Philipps Universit€ at Marburg, Marburg, Germany M. Najam-Ul-Haq, Institute of Analytical Chemistry and Radiochemistry, Leopold- Franzens University, Innsbruck, Austria Wolfgang J. Parak, Fachbereich Physik, Philipps Universit€ at Marburg, Marburg, Germany C. Petter, Institute of Analytical Chemistry and Radiochemistry, Leopold-Franzens University, Innsbruck, Austria Roberto Pilloton, ENEA C.R. Casaccia, Rome, Italy M. Rainer, Institute of Analytical Chemistry and Radiochemistry, Leopold-Franzens University, Innsbruck, Austria xii CONTRIBUTORS
- 18. Nitsa Rosenzweig, Department of Chemistry and the Advanced Materials Research Institute, University of New Orleans, New Orleans, Louisiana Zeev Rosenzweig, Department of Chemistry and the Advanced Materials Research Institute, University of New Orleans, New Orleans, Louisiana Lifang Shi, Department of Chemistry and the Advanced Materials Research Institute, University of New Orleans, New Orleans, Louisiana Sergei Smirnov, Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico Andrew J. Sutherland, Department of Chemical Engineering and Applied Chemistry, Aston University, Birmingham, United Kingdom R. M. Vallant, Institute of Analytical Chemistry and Radiochemistry, Leopold- Franzens University, Innsbruck, Austria Walter Vastarella, ENEA C.R. Casaccia, Rome, Italy Ivan Vlassiouk, Department of Physics and Astronomy, University of California, Irvine, California Andrew J. Wain, Department of Chemistry and Biochemistry, California State University, Los Angeles, California Jianxiu Wang, School of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan, China Gregory G. Wildgoose, Physical and Theoretical Chemistry Laboratory, Oxford University, Oxford, United Kingdom Gary Withey, Engineering Division, Brown University, Providence, Rhode Island Elicia L. S. Wong, Physical and Theoretical Chemistry Laboratory, Oxford University, Oxford, United Kingdom Ying Xu, Department of Chemistry, East China Normal University, Shanghai, China Feimeng Zhou, Department of Chemistry and Biochemistry, California State University, Los Angeles, California Xu Zhu, School of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan, China CONTRIBUTORS xiii
- 19. SERIES PREFACE Nanoscience and nanotechnology refer broadly to a field of applied science and technology whose unifying theme is the control of matter on the molecular level in scales smaller than 1micrometer, normally 1 to 100 nanometers, and the fabrication of devices within that size range. Nanotechnology alsorefers to themanufacture ofnano- sized systems that perform specific electrical, mechanical, biological, chemical, or computing tasks. Nanotechnology is based on the fact that nanostructures, nanodevices, and nanosystems exhibit novel properties and functions as a result of their small size. It is a highly multidisciplinary field, drawing from such subjects as applied physics, materials science, colloidal science, device physics, supramolecular chemistry, and mechanical and electrical engineering. Given the inherent nanoscale functions of the biological components of living cells, it was inevitable that nanotechnology would also be related and applied to the life sciences through the application of nanoscaled tools to biological systems as well as the uses of biological systems as templates in the development of novel nanoscaled products. Much speculation exists related to what new science and technology may result from the synergy of the disciplines mentioned. Nanotechnology can be seen as an extension of existing sciences to the nanoscale level. Two primary approaches are used in nanotechnology. In the bottom-up approach, materials and devices are built from molecular components which assemble them- selves chemically by principles of molecular composition. In the top-down approach, nanoobjects are constructed from larger entities without atomic-level control. The impetus for nanotechnology comes from a renewed interest in colloidal science, coupled with a new generation of analytical tools such as the atomic force microscope and the scanning tunneling miccroscope. Combined with refined processes such as electron-beam lithography and molecular-beam epitaxy, these instruments allow the deliberate manipulation of nanostructures and have led to the observation of novel phenomena. Examplesof nanotechnology in modern use are the manufacture of polymersbased on molecular structure and the design of computer chip layouts based on surface science. Despite the great promise of numerous nanotechnologies, such as quantum dots and nanotubes, real commercial applications have mainly used the advantages of colloidal nanoparticles in bulk form, such as in suntan lotion, cosmetics, protective coatings, and stain-resistant clothing. xv
- 20. Research in the field of nanoscience and technology is very active and is expected to remain so for the foreseeable future. The Wiley Series in Nanoscience and Nanotechnology will be focused on the following important topics: * Basic nanoscience * Nanotechnology tools * Nanomaterials * Nanobiosensors * Nanobiotechnology * Nanotechnology for environment. * Nanotechnology and energy * Nanotechnology and electronics/computers * Nanotechnology and ethical issues We welcome coverage of other topics in response to issues that arise in coming months. All topics will be edited by experts the various nanoscience and nanotech- nology fields and will serve as a reference source for this new and exciting science and technology. Collaborations are welcome! ARBEN MERKOÇI Series Editor Bellaterra, Catalonia, Spain July 2008 xvi SERIES PREFACE
- 21. PREFACE The implementation of nanoscience and nanotechnology achievements in bioanalysis is the main objective of this book, whose aim is to explaining to readers several strategies related to the integration of nanomaterials with bioanalytical systems as one of the hottest topics of today’s nanotechnology and nanoscience. Novel concepts are shown, together with practical aspects of nanoscale material’s integration into biosensing systems. This integration is due to the capacity of nanomaterials to provide special optical or electrical properties as well as stability and to minimize surface fouling of the sensing systems where they are being integrated. Various nanomaterials, including carbon nanotubes, nanoparticles, nanomagnetic beads, and nanocomposites, are being used to develop highly sensitive and robust biosensors and biosensing systems. The materials mentioned are attractive probe candidates because of their (1) small size (1 to 100 nm) and correspondingly large surface-to-volume ratio; (2) chemically tailorable physical properties, which relate directly to size, composition, and shape; (3) unusual target binding properties; and (4) overall structural robustness. This is an interdisciplinary book dedicated to professionals who have an interest in the improving the current bioanalytical techniques and methodologies by implement- ing nanoscience and nanotechnology in general and nanomaterials in particular. The goal is to present the most recent scientific and technological advances as well as practical bioanalytical applications based on the use of nanomaterials. It will be an important reference source for a broad audience involved in the research, teaching, learning, and practice of nanomaterial integration into biosensing systems for clinical, environmental, and industrial applications. Bioanalysisingeneralandbiosensorfieldsinparticularareshowingspecialinterest in nanobiomaterials. Nanomaterials bring several advantages to bioanalysis. Their immobilization on sensing devices generates novel interfaces that enable sensitive optical or electrochemical detection of molecular and biomolecular analytes. More- over, they are being used as effective labels to amplify the analysis and to design novel biomaterial architectures with predesigned and controlled functions with interest for several applications. Achieving higher sensitivities and better and more reliable analysis are one of the objectives of DNA probes and immunoanalysis. Carbon nanotubes (CNTs) represent one of the building blocks of nanotechnology. With one hundred times the tensile strength of steel, thermal conductivity better than that of all but the purest diamond, and electrical conductivity similar to that of copper but with the ability to carry much higher currents, CNTs seem to be a very interesting xvii
- 22. material. Since their discovery in 1991, CNTs have generated great interest for future applications based on their field emission and electronic transport properties, high mechanical strength,and chemical properties. The structural and electronic properties of CNTs provide them with distinct properties for facilitating direct electrochemistry of proteins and enzymes compared to other types of materials used so far. The bioelectrochemistry and optical properties, along with some other interesting features of CNTs coupled to several bioanalytical procedures, are also presented. Nanoparticles of a variety of shapes, sizes, and compositions are changing the bioanalytical measurement landscape continuously and so are also included. Nano- particles can be used, for example, in quantification or codification purposes, due to their chemical behavior, which is similar to that of small molecules. They also provide novel platforms for improving the activity of DNA probes, antibodies, or enzymes. Nanoparticles may be expected to be superior in several ways to other materials commonly used in bioanalysis. They are more stable and cheaper, allow more flexibility, have faster binding kinetics (similar to those in a homogeneous solution), and have high sensitivity and high reaction rates for many types of multiplexed assays, ranging from immunoassays to DNA analysis. Improving the current bionalytical techniques and methodologies and finding novel concepts and applications in bioanalysis are two of the most important objectives of nanotechnology and nanoscience today. Advances in nanotechnology are affecting existing technologies and leading to the development of novel bioanalytical tools and techniques through improvements in precision and speed, lower sample requirements, and the ability to perform multiple detections in smaller devices. Novel biosensing systems that require less sample material are being developed so as to perform sophisticated tests at the point of care (e.g., blood analysis using a handheld device within a few minutes) and make possible the multiplex analysis (i.e., simultaneous and fast analysis of more than one variable). Analysis of the structure of living cells in real time and in the intact organism (in vivo) as opposed to using laboratory-prepared samples (in vitro), as well as molecular analysis (DNA, RNA, and protein analysis), including biosensors based on nanomaterials, represent challenges not only for basic research in nanotech- nology but for the bioanalysis community, which is willing to see new input from this novel area of research that is developing so fast. In this context the book introduces novel concepts that are being achieved in the area of bioanalysis based on the fact that nanomaterials are opening up new opportunities not only for basic research but overall, are offering new tools for real bioanalytical applications. The focus is on the latest tendencies in the field of nanoparticles, carbon nanotubes, and nanohannels: integration into bionalytical systems, including sensors and biosensors. The area of biosensing using nanotechnology is providing the information necessary for real applications of nanomaterials and related nanotechnologies. The book should act as a very interesting interface of information between complemen- tary fields, thus opening up new opportunities for researchers and others. It will also support doctoral students and those involved in learning and teaching nanobiotech- nological applications in bioanalysis. xviii PREFACE
- 23. How does the bionalytical community implement the spectacularly bright future offered us by nanoscience? What are the challenges facing bioanalysis in our nanoscale future? How do we move from an almost science fiction level toward real-world outcomes in nanotechnology? The bioanalytical community will be better able to respond to these questions in the future after reading this book, which not only compares nanomaterials to conventional materials but also gets inside the response mechanisms related to such improvements. The book’s fifteen chapters deal with the most successful nanomaterials used so far in biosensing: carbon nanotubes, nanoparticles, and nanochannels, including detection strategies ranging from optical to electrochemical techniques. Each chapter provides a theoretical overview topic of interest as well as a discussion of the published data with a selected list of references for further details. The book provides a comprehensive forum that integrates interdisciplinary research and development of interest to scientists, engineers, researchers, manufacturers, tea- chers, and students in order to present the most recent advances in the integration of nanomaterialswithbioanalysisastheyrelatetoeverydaylife.Thebookpromotesthe use of novel nanomaterials in biosensors and biosensing systems through introduc- tion of the highest-quality research in the field of nanomaterial-based bioassay. ARBEN MERKOÇI Bellaterra, Catalonia, Spain July 2008 PREFACE xix
- 25. CHAPTER 1 Carbon Nanotube–Based Sensors and Biosensors RICHARD G. COMPTON, GREGORY G. WILDGOOSE, and ELICIA L. S. WONG Physical and Theoretical Chemistry Laboratory, Oxford University, Oxford, United Kingdom 1.1 Introduction to the structure of carbon nanotubes 1.2 Electroanalysis using CNT-modified electrodes 1.2.1 Historical background 1.2.2 Electron transfer at graphitic carbon electrodes: The role of edge-plane defects 1.2.3 Exceptions to the rule that edge-plane defects are the important electroactive sites on CNTs 1.3 Advantageous application of CNTs in sensors: pH sensing 1.4 Carbon nanotube–based biosensors 1.4.1 Introduction 1.4.2 Surface functionalization of carbon nanotubes and configuration of a CNT-based electrochemical biosensor 1.5 Using CNTs in biosensor production for medical diagnostics and environmental applications 1.5.1 Medical diagnostics 1.5.2 Environmental applications 1.1 INTRODUCTION TO THE STRUCTURE OF CARBON NANOTUBES In recent years carbon nanotubes (CNTs) have attracted, and continue to attract, considerable interest in a wide variety of scientific fields, not least that of the electroanalytical and bioelectroanalytical communities. However, before we summa- rize some of the main properties of CNTs that make them an interesting and often ideal material to use in electrochemical sensors and biosensors, let us begin by highlighting perhaps the most common misconception found in the literature concerning Biosensing Using Nanomaterials, Edited by Arben Merkoçi Copyright 2009 John Wiley Sons, Inc. 3
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- 28. Bertmount av — Arthur h 458 Wellesley e —Arthur brklyr r 38 Lanark av (York Twp) OR 2655 — Arthur E leather ctr Aristocrat Leather G jods r 12 Wiltshire av MU 1632 —Arthur H h 120 Argyle LL 6427 — Audrey H Mrs stenog Bank of N S h Brumwell rd (Highland Creek) — Barbara r 1 Elm av — Barbara Mrs stenog Terminal Credit Union Ltd r 23 Muriel av —Beatrice h 1, 100 Tyndall av ME 9098 —Beatrice Mrs h 37 Beaty av KE 3308 — Benj W engineer CPR h 22 Corbett av (York Twp) MU 1931 — Bernard J trk drvr r 61 Hamilton HA 3091 — Bertha (wid Robt) h 23 Cassels av HO 5356 — Betty emp American Hat Co r 38 Dartnell av MI 2209 — Beverley H plmbr’s apprentice Fulford Tucker Ltd h 607 Yonge KI 43^5 — Brenda L copy elk Star r 372 Sammon av (E Y) --Brian N investment counsel 500, 36 Toronto EM 3-6736 h 461 Lytton blvd (Nth Y) OR 6481 --Bros Ltd Wm M Barrett pres, Frank A Barrett vlce-pres, Lillian L Barrett sec- treas fruit vegetables 82 Front e EM 4-9231-2 • -Bruce r 67 Olive av LA 2456 --C Gordon vlce-prin tchr McMurrich Pub Schl h 402, 707 Eglinton av w (Fst H) OR 9119 --Campbell M Dept of Mines (Ont) h 20 Beechwood cres (E Y),GL 5226 --Cecil emp Adams Brands r 14 Rose av — Chas insp Comstock h 46 Humberside av JU 1288 -- Chas slsmn Wembley Clothes r 447 Clendenan av LY 1160 — Chas L fitter Gas Co h 345 Leslie GE 5849 —Chas M slsmn NeUsons h 56 Riverview gdns (York Twp) LY 0582 — Christopher D PBX repairmn Bell Tel h 116 Wembley rd (Fst H) OR 4593 — Clara (wid John J) h 4, lA Vermont av LL 0207 --Clarence shpr Amer News r 218 St Helens av — Clarence F emp A V Roe h 190 Hastings av HA 7494 —Clifford sis statistics Stafford Foods r 7 Columbine av — Colin T messr Brinks Exp h 24 Bertmount av HA 4762 --Co Ltd The J D Tweedy dist sis mgr roofing, chemicals road materials s s Keating Saulter GL 3591-2-3 — Cyril F sis rep Addressograph-Multigraph r 18 Norton av ,, , , --D E asst dir of Fire Training Fire Marshall (Ont) h 49 Meadowvale av (Scar) — Dave steel wkr r 59 Marchmount rd LL 1466 --David wtr Graymar Hotel h 96 Rainsford rd HO 6726 --David G mech Logan Motor Service r 73 Brooklyn av GL 7400 — Dominic pntr’s hlpr Royal York Hotel r 61 Hamilton HA 3091 --Donald r 85 Shanly KE 3929 --Donald off boy Prov Tire r 40i Greensides av — Donald E prntr Gestetner r 59 Withrow av —Donald V r 198 Howland
- 29. av LO 4447 —Dorothy A (wid Arthur L) h 23, 66 Beech av HO 7620 — Douglas r 185 McRoberts av KE 5804 —Edith Mrs h 73 Brooklyn av GL 7400 —Edith Mrs r 50 Charles e RA 5522 --Edith G C h 3, 579 Jarvis RA 4538 — Edna emp Woman’s Bakery r 221 Vaughan rd (York Twp) — Edna Mrs opr Parker Pen r 1203 Bloor w ME 7913 -- Edna M studt r 211, 2001 Bloor w JU 4008 — Edwd engravers -asst Reliance Engravers r 60 Myrtle av --Edwd Ont sis mgr Crosley Radio Television h 133 Cosburn av (E Y) HA 4011 —Edwd trk drvr Bushell Haulage r 65 Hamilton GE 8667 „ — Edwd J messr Burns Bros Denton h 8, 592 Church —Edwd M (Acme Mailing Service) (77A Adelaide w) --Edwd N elk Ont Hydro r 48 Athlone rd (E Y) -- Elizth opr W W McGee Co Ltd r 400 Euclid av KI 1091 — Elsie emp Parisian Laundry r 32 Laing HA 3130 BARRETT — Emily (wid Wm) exec asst to div mgr Twentieth Century-Fox Corp h 165 Castlefleld av HU 9-1493 — Emma (wid Henry) h 248 Linnsmore cres (E Y) — Erna E h 31 Pauline av LO 6527 — Ernest loader Borden Co r 623 Dupont — Ernest slsmn A Bradshaw Son h 22 Cherrywood av (York Twp) KE 0160 — Ernest wall washer St Michael’s Hosp r 210 Carlton MI 0044 — Ervin R (Joan Doreen Dress Co) h 190 York MUls rd (Nth Y) —Ethel Mrs h 304, 58 Maitland KI 5676 — Ethel Mrs sis elk Eatons r 167 Donlands av — Ethel M nurse Bell Tel r 232 Heath e HU 8-0034 — Eveline M typist Candn Simety r 8 Mack av — F W Co Ltd F W Barrett pres, C H Wilson vice-pres, B M Wilson sec, F J Wallace treas printing slaty 45 Lucy av (Scar) GR 1118 — Finley opr TTC h 39 Morgan av (Thornhill) — Florence Mrs emp Bassil’s GrlU r 95 Aileen av (York Twp) LY 7850 . — Frances Mrs h 227 Pearson av OL 4373 — Frances (wid John) h 1 Battenberg av HO 0961 — Francine planten press opr Imp Varnish r 133 Cosburn av (E Y) HA 4011 — Francis elk Can Life h 25 Murdock av HO 5315 — Francis E (West End Florist) h 2825 Dundas w MU 9697 — Francis E emp Westons h 623 Dupont LO 1836 — Frank candy mkr Hunts h 235 Broadway av HU 8-4750 — Frank comml artist Simpsons h 75 Barrington av (E Y) OX 6208 — Frank A vlce-pres Barrett Bros Ltd h 30 Duart Park rd GR 0189 -- Frank J Candn vlce-pres Inti Brotherhood of Bookbinders #28 h 378 Broadway av (Nth Y) MA 3482 — Frank J elk Candn Oil h 928 Ossington av LO 1906 — Frank J prof engineer Ont Hydro r 12
- 30. Queen Anne blvd (Wstn) — Frank M foremn Genl Steel Wares h 287 Mortimer av (E Y) HA 8535 — Frank W pres F W Barrett Co Ltd h 21 Leith pi MA 1255 — Fred slsmn Can Bread h 75 Barrington av (E Y) OX 6208 —Fred S (Canadian Steel Moulds) h 2611 Kingston rd (Scar) —Fred W h 29 Fifth (New T) — Fredk tester Neptune Meters h 7 Park blvd (Long B) — Fredk emp Price Air Conditioning h 121 Boultbee av RI 1927 —Fredk W tchr Northern Vocational Schl h 56 Killdeer cres (Leas) MA 2522 — Fur Co (Geo Barrett John Bromwich) 87 Peter EM 4-9588 — Geo r 37 Beatrice LL 8308 — Geo (Barrett Fur Co) h 26 Rosebury rd (Fst H) OR 4059 --Geo engineer Clean-Rite Ltd h 114 Government rd (Etob) LY 9292 — Geo slsmn h 587 Wellington w EM 8-2178 — Geo stk elk Eatons r 75 Wamsley blvd — Geo F asst acet Sinclair Valentine r 114 Government rd (Etob) LY 9292 — Geo H barber 970 Yonge h same — Geo J apprentice G A Davis Prntg r 16 Givins — Geo L emp Photographic Survey r 676 Pharmacy av (Scar) — Geo N elk Bank of Tor r 276 Gowan av (E Y) GL 5562 — Geo P messr C P Exp h 331 St Johns rd (York Twp) MU 1942 — Geo R suprvsr order dept Kendall Co (Can) Ltd res Scarboro —Geo W mgr Hopkins Hardware h 15 Harcourt av HA 2745 — Gerald r 833 Pape av GL 6593 — Gerald emp Kruger Mfg Co r 14 Emerson av OL 2141 — Gerard K chainmn CNR r 10 Sandford av HA 1664 — Gilbert R (Starr Barrett) h 191 Millwood rd MA 5305 — Gladys cash Royal York Hotel r 298 Withrow av RI 2649 — Gloria J wax caster Goldsmith Bros r 69 Rose av RA 6379 — Grace M (wid E M) h 100 Glenview av HU 9-3930 — Hannah r 47 Bowmore rd RI 5615 — Harold emp Smart’s Gas Stn r 38 DartneU av MI 2209 — Harold spray pntr Candn Acme Screw Gear r 541 Glenholme av (York Twp) OR 2308 — Harold suprvsr Radio Valve h 70 Hatherley rd (Y ork Twp) --Harold B acet Ont Hydro h 20 Ravlna cres GL 0976 — Harold C with Bell Tel r 185 Hiawatha rd GE 9807 — Harry h 816 Manning av ME 5812 — Harry emp Simpsons r 191 Rosemount av KE 2659 -Harry slsmn r 7 Madison av KI 1229 — Harry O tchr Eastern High Schl of Com h 56 Laurelcrest av (Wilson Hts) — Harry W incinerator stoker Dept St Clng h 517 Quebec av RO 1624 — Helan r 92 Stafford EM 3-8850 — Helen emp GreenhUl Drug Store r 262 Erskine av HU 8-7222 — Helen R pckr Weston Bakeries r 632
- 31. Dupont — Henry pres Dominion Woollens Worsteds Ltd h 106 South dr MI 7112 — Herbt trk drvr Bushell Cartage h 35 Oak EM 8- 5105 — Herbt J design engineer Ont Hydro h 181 Stibbard av MA 0416 — Home Portrait Service (Fred D Peters) photo 275 Indian rd LO 9416 --Howard r 273 Major —Howard A emp Norm Smart Service Stn r 162 Gloucester gr — Howard F asst buyer Mlnneapolls- Honeywell r 287 Mortimer av — Howard H artist h 26 Sammon av (E Y) GL 5270 — Howard J elk Meteorological Serv h 232 Heath e HU 8-0034 --Howard M studt r 21 Leith pi MA 1255 — Hubert h 58 Dovercourt rd KE 3091 —Hugh sr suprvsr Borden Co h 1, 105A Roncesvalles av LA 6341 --Ina (wid Harry) h 45 Wright av LL 0081 — Irene r 592 Sherbourne RA 3142 — Isaiah brass wkr Anaconda Amer Brass h 65 Tamarac av (Long B) — J Miss stenog Sun Oil r 469 Milverton blvd — J (wid Geo) h 263 McCaul — J Flavelle solicitor Imp Oil — Jack foremn Trane Co r 12 Laburnham av (Long B) — Jas wrehsemn Sherwln Williams h 32 Laing HA 3130 BAR BARRETT BARRETT — Jas A acet r 102 Lawlor av GR 0408 — Jas B supt C P Exp h 211, 2001 Bloor w JU 4008 — Jas F elk Conti Can r 29 Fifth (New T) —Jas S h 61 Hamilton HA 3091 —Janet L stenog Imp Oil r 58 Dovercourt rd KE 3091 — Jean h 2, 142 Carlton KI 4305 — Jean brides counsellor Eatons r 31 Pauline av LO 6527 — Jean nurse r 888 Coxwell av (E Y) GE 8762 — Jeanne sec G Arnold Henry r 142 Carlton — Jennie stenog M M Angus Associates h 138 Wanless av MA 5706 — Joan typist Reed Shaw McNaught r 132 Bellefair av HO 0563 — Joan E stenog Sun Oil Co Ltd r 211, 2001 Bloor w JU 4008 •■-John r 511 Carlaw av GL 1064 —John h 61 Pinewood av (York Twp) — John emp Eastern Steel h 85 Lindsey av LL 5400 — John C staff training officer P O h 31 Soudan av HU 9-8652 — John C trk drvr Can Cartage Systems h 92 Stafford EM 3-8850 —John E h 38 Dartnell av MI 2209 — John E bkpr Ed Provaa Ltd h 1, 10 Windall av (Wstn) CH 1-1583 ' — John E trk drvr S A Industrial Dept h 155 Rhodes av HA 7449 — John S slsmn Consolidated Glass Industries h 35 Cedarcrest blvd (E Y) OX 7971 — John W elk IBM r 31 Soudan av HU 9-8652 — Johnson J barber h 42 Hannaford HO 4788 — Joseph carp h 23 Howie av — Joseph trk drvr Bushel Haulage h 35 Oak EM 8- 5105 — Joseph K slsmn Weston’s Bakeries r 198 Howland av LO
- 32. 4447 — Josephine furrier 1266 King w LA 4151 h same —Joy Mrs h 1613 Keele (York Twp) MU 5678 — Julia (wid J H) emp Tor Western Hosp h 198 Howland av LO 4447 — Kathleen Mrs h 75 Walmsley blvd MO 5861 — Kathleen (wid Basil L) h 279 Christie LO 1492 — Kathryn A accounting elk Premier Trust r 288 Erskine av --Keith R elk Ont Hosp Assn Blue Cross h 296 Crawford KE 9954 —Kenneth h 43 Nordale cres (Nth Y) CH 1-5548 — Kenneth emp Silverwoods h 298 Withrow av RI 2649 — Kenneth trk drvr h 393 Roxton rd OL 5537 — Kenneth C emp CNR r 55 Fuller av OL 1504 — Kenneth R (Joan Doreen Dress Co) r 223 Wilfred av (Willowdale) — Laurence h 9 Marion LA 2366 — Lawrence P emp Goodyear Tire h 12 Albert av (Mim) — Lena Mrs h 614 Dundas e EM 6-3855 — Leonard J acet S J Brooks Co h 9 Tenth (New Toronto) — Leslie C sec Bank of Tor h 39 Kappele av MO 6421 — Leslie T block lathe opr Candn Wallpaper Reg N Boxer Div h 104 Eighth (New T) — Lillian E stenog Excelsior Life Ins r 23 Howie avenue — Lillian L sec-treas Barrett Bros Ltd r 61 Nealon av (E Y) HA 9709 — Llndberg btehr Swift Candn h 2071A Dufferin (York Twp) — Loretto A typist Ont Hosp Assn Blue Cross r 33 Strader av (York Twp) RE 5587 — M Eileen priv sec Home Ins h 76 Rowanwood av — M J Miss elk Confed Life Assn r 92 Linnsmore cres — Margt Mrs h 100 Massey EM 8-5210 — Margt slsgirl Woolworths r 46 Gloucester — Margery stenog Dickie Constn Co Ltd h 138 Wanless av MA 5706 —Martha (wid Jas T) h 26 Somerset av LO 0898 — Martin gdnr Parks Dept h 6 Apple Grove av GE 9036 — Mary r 656 Coldstream av (Nth Y) RU 1-1292 — Mary r 23 Howie av — Mary reporter Tor Credits r 151 Westminster avenue — Mary Mrs h 5, 1446A Yonge MI 8360 —Mary (wid Jas) h 301 Westmoreland av LL 6038 — Mary (wid Thos) r 2 Glen Stewart av GR 7856 —Mary A (wid Wm) r 114 Gowan av (E Y) HA 3832 — Mary H (wid John) r 30 Greenwood av HA 4518 — Maud Mrs r 48 Frances av (Etob) —Maury orderly Sunnybrook Hosp r 33 Strader av [York Twp) RE 5587 — Max (Max Barrett Furs) h 4 Glebe rd e HU 9- 8086 — Max Furs (Max Barrett) furrier 2019 Yonge HU 9-8086 — May (wid Alex) h 55 Fuller av OL 1504 — Melville brklyr r 248 Linnsmore cres n (EY) — Melvin J slsmn Iron Firemn h 7 Lumbervale av LL 9647 — Michael h 129 Rose av RA 6159 — Michael E automatic opr C N Tel r 382 Milverton blvd
- 33. —Mildred A emp Banting Inst r 21 Leith pi MA 1255 — Molly (wid Richd) h 4O5 Greensides av — Monta M Mrs h 106, 51 Grosvenor RA 8622 —Mottle pres Downes Barrett Ltd h 66 Burnaby blvd HU 9- 3738 —Murray cUc Stone, Smith Conway r 2019 Yonge — Murray L slsmn Rusco Ltd r 378 Broaaway av (Nth Y) MA 3482 — Naomi nurse r 263 Lauder av (York Twp) KE 7084 — Nathan T wrehsemn Christie’s Bread r 50 Langley av GE 5714 — Nelson K trk drvr Booth Brick h 46 Lloyd George av (Etob) — Norine nurse St Michaels Hosp r 33 Strader av (York Twp) RE 5587 — Norma with Natl Trust r 232 Heath e — Norman elk Ont Hydro r 48 Athlone rd (E Y) HA 6283 — Norman E parts mgr Byers Motors h 248 Kingswood rd OX 6102 — Oliver C emp Lever Bros h 14 King George dr (York Twp) JU 7941 — Patricia Mrs h 50 Darling av RA 2680 — Pattrlcia J paper box hlpr Nellsons r 25 Murdock av — Percy G porter Can Perm Mort h 479 Jones av — R Lloyd emp W J Flynn Co h 288 Erskine av MA 3659 — Ralph studt r 98 Brooklyn av HA 1746 --Ralph E acet Bank of Mont r 54 Clarendon av —Raymond E drftsmn A V Roe r 96 Dewhursl blvd GL 7081 Alphabetical, White Page 77
- 34. BAR BARRETT BARRETT — Regd opr TTC h 18 Merritt rd (E Y) — Regd L mgr Liquor Control Bd of Ont (802 Lakeshore rd (New T) h 52 Third (New T) — Regd E lab Walter Davidson Co h 508 Old Orchard gr (Nth Y) RE 7509 --Rlchd malnt Candn Arsenals h 224 Withrow av GE 3390 — Rlchd studt r 40i Greensldes av —Rlchd E prof head of dept U of T h 116 Ridge dr HU 9-6440 —Rlchd H elk A V Roe r 407 WlUard av JU 3587 —Rlchd P (Barrett, Seguln Co) h 16 Rosemary Lane (Fst H) MO 9821 —Rlchd S vlce-pres Diamond Taxicab Assn Toronto Ltd h 52 Glengowan rd HU 9-9013 —Rita L J tel information elk CNR r 129 Itose av — Robt apprentice Art Wire Iron h 153 King Edward av (E Y) GR 9544 — Robt sheet metal wkr Bd of Educ r 133 Cosburn av (E Y) HA 4011 —Robt trav W B McRae h 33 Traymore cres (York Twp) —Robt J mgr Rhlnette Ltd res Bayview ct, Sheppard av (Lansing) — Roderick r 360 Pacific av JU8009 — Roger lab Lennox Constn Co r 248 Linnsmore cres (E Y) —Roger F utility man Shell Oil h 15 Brooklyn av — Ronald slsmn YoUes Furn r 9 Stavebank rd (Pt Credit) —Rose (wid Sidney) h 172 Joicey blvd (Nth Y) --Ross r 25 Southvlew av LL 7607 --Ross B elk Egllnton Baptist Church h 27 Belcourt rd HU 9-6800 — Roy emp CNR r 33 Holly HU 8-7102 --Roy C sis statistics elk Goodyear Tire h 29 Third ^ew T) --Ruth h 713 Greenwood av GE 6658 —Ruth Mrs prlv sec Gooderham Worts res A^ncourt —Sami T Customs Excise h 142 Deloralne av HU 8-0293 — , Seguln Co (Rlchd P Barrett Alfred H Seguln) stock brkrs bond dlrs 1203, 330 Bay EM 8-7631 — Shirley elk Mason, Foulds, Arnup, Walter Weir r 587 Wellington w — Sidney A r 295 Blackthorn av (York Twp) MU 8483 — Simeon perm force h 8 Mack av (Scar) HO 7448 — Stanley emp Eatons r 747 Palmerston av LA 3487 — Stanley furn mover h 76 Gloucester MI 0158 — Stanley lab r 88 Gloucester RA 4445 — Stanley A stkpr Eatons h 41 LUllngton (Scar) HO 8952 — Sydney F carp Dickie Constn h 250 King Edward av (E Y) HO 0563 — Thelma I mach opr CNR r 55 Pine Crest rd — Thos assmblr Moffats h 37 Jesmond av (York Twp) OR 5337 — Thos emp Sunnybrook Hosp h 119 Guestville av (York Twp) LY 5031 — Thos gdnr h 234 Ranlelgh av HU 9-6559 — Thos trk drvr r 38 Dartnell av MI 2209 — Thos L metal wkr Star h
- 35. 292 Melrose av RE 1465 — Vera Mrs elk Dom Stores h 192 Perth av —Vera (wld Rlchd) pantograph opr Superior Mfg h 266 Hiawatha rd GL 3714 — Vincent J slsmn Shaw Wright h 33 Strader av (York Twp) RE 5587 —Violet Mrs h 16 Louisa (Mlm) — Violet L typist CGE r 8 Falwyn av (York Twp) OR 8248 — W Bruce asst personnel mgr Prudential Ins Co of America h 119 HlUmount av (Nth Y) OR 7591 — W R lab Exlde Batteries r 38 Dartnell av — Wallace W h 123 Dunvegan rd (Fst H) MA 3233 — Walter drvr Simpsons h 60 Oak EM 4-4702 — Walter elk Eatons r 747 Palmerston av — Walter furn assmblr Eatons h Nine Oaks, Rivercourt dr (Rouge Hill Valley) — Warren A pntr Cullen CuUen r 2, 1146 College --Wendell D emp Inti Harvester r 35 Breadalbane —Wilbert h 10 Fennlngs LA 6521 — WUhelmlna M elk York Twp Hydro h 295 Blackthprn av (York Twp) MU 8483 — Wm h 372 Whitmore av (York T*ip) OR 8711 — Wm chauf h 485 Davlsvllle av MO 2452 — Wm contr r 614 Dundas e EM 6-3855 — Wm A bridge opr Tor Highways Commn h 10, 14 Bonnyvlew dr (Etob) MU 2535 — Wm A pekr Maple Leaf Milling Co h 1961 Keele (York Twp) — Wm C sis correspondent Candn Line Materials h 19 Medonte av (Scar) — Wm C with Tor Hydro h 4, 177 Davlsvllle av — Wm F Insp A V Roe h 25 Felmo cres (Nth Y) CH 1- 2736 — Wm J firemn Ont Hydro h 182 Lambton av (York Twp) MU 5514 — Wm J mlllhand Tor Elevators h 22 Thora av (Scar) OX 6076 — Wm J slsmn Wonder Bread h 372 Sammon av (E Y) HA 9150 — Wm M pres Barrett Bros Ltd h 61 Nealon av (E Y) HA 9709 — Wm S h 297 Booth av GL 1329 — Wm S conveyor opr Goodyear Tire res Malton — Wm V (Barre Monument Co) r 64 Old Colony rd (York MUls) — Wm W barr Kingsmll), Mills, Price Fleming h 73 Roxborough dr KI 1719 Barrette Donald J lab Dept St Clng r 44 Vernon LY 1600 — Ida emp Tor Terminals h 166 Davenport rd PR 3868 —Jeanette hsekpr r 95 Dunloe rd (Fst H) MO 8968 —Joseph mech h 51 Fifteenth (New T) — Louis emp Rowntree Co h 44 Vernon LY 1600 — Maurice G with Tor Hydro h 81 Langford av — Norman h 14 Stonehouse cres OL 2620 Barrlage Barbara Mrs savings mach opr Bank of Com r 89 Larchmount av — Harold C trk drvr York Trading r 661 Cosburn av (E Y) HO 1244 — Harold E fruit mgr York Trading h 661 Cosburr av (E Y) HO 1244 — Leo F foremn Can Wire Cable h
- 36. 2, 751 Carlaw av GE 0721 Barrlck C Grey tchr Cantab College h 62 Lyndhurst av KI 4764 — Fredk caretkr Sllverthorn Pub Schl h 22 Holwood av (York Twp) JU 4538 — Gwendolyn A elk Tor Carpet r 593 Runnymede road --Harold L elk CPR h 154 Park Home av (Nth Y) — Mellvllle J wrapper opr Christie’s Bread r 482 Parliament — Ralph h 267 Albany av LA 9555 BARRICK —Ralph N h 166 Briar Hill av MO 3065 Barrie A Russell engineer CNR h 205 Lake Shore dr (New T) --Agnes Mrs h 4, 245A Gerrard e —Agnes M stenog Wlx Accessories Corp h 54 Southwood dr HO 1649 — Albt emp Dunlop Tire r 119 Delaware av ME 7043 — Alex L slsmn Brown’s Sporting Goods h 59 Spruce HUl rd HO 1223 — Arnott emp Borden Co r 206 Livingstone av (York Twp) OR 6704 — Chas W pattern mkr Stand Pattern h 3 Pepler av (E Y) GL 6191 — Danl F processor Dodge Chemical Co (Can) Ltd h 21 Louisa (Mlm) — David C Insp Genl Accident Assce h 104, 6 Anglesey blvd (Etob) — David M acet London Lancashire Ins h 301, 18 Tichester rd (York Twp) ME 2362 — Donald G express messr CPR r 109 , 240 Northcllffe blvd (York Twp) LL 8380 — Doris sis elk Eatons r 3 Pepler av (E Y) GL 6191 — Dorothy J Mrs elk Birks r 104, 6 Anglesley blvd (Etob) — Elizth R exec sec Natl Business Pub h 54 Southwood dr HO 1649 — Eileen T prlv sec Ont Research Foundation r 21 Louisa (Mlm) — Florence (Amherst Card Guild) h 81 Don Valley dr (E Y) HA 2886 — Geo I auto garage 1993-1995 Danforth av OX 1223 r 585 Rhodes av GL 4265 — Geo N mech Geo I Barrie h 585 Rhodes av GL 4265 — Gordon sheet metal wkr h F, 333 Harbord ME 6108 — H J path U of T Dept of Pathology Bacteriology res King — J W slsmn Adams Furn r 34 Elgin av RA 5933 — Jas emp CGE h 315 Lauder av (York Twp) RE 6219 — Jas ydmn Geo W Crothers h 26 Hillary av (York Twp) LY 7711 — Jas N trk drvr Willards Choc r 26 Hillary av (York Twp) LY 7711 — John emp A V Roe r 235 Clendenan av LY 9174 — John J h 92 Crescent rd — Kenneth r 10 Northvlew av (Scar) OX 3964 — Lawrence L with Tor Hydro h 132 Horsham av (WlUowdale) — Lorna mach opr York Trading r 52 Dilworth cres — Madeline Mrs sis elk Eatons r 25 Wenomah dr (Pt Credit) --Margt r 11 St Hilda’s av HU 9-7709 — Marjorie E stenog S S Kresge r 3 Pepler av (EY) GL 6191 — Masle Mrs emp Daughters of the Empire Hosp r 54
- 37. Sheldrake blvd — Nat carp Soules Constn Co h 924 Logan av GE 4179 — Raymond E janitor Crouse-Hinds r 3 Pepler av (E Y) GE 6191 — Robt r 54 Southwood dr HO 1649 — Robt chauf Daughters of the Empire Hosp r 54 Sheldrake blvd —Robt H steelwkr Dom Bridge r 75 Arlington av KE 3077 — Robt J dlst sis mgr Easy Washing Mach h 79 Yorkvlew dr (WlUowdale) —Roger O elk CIL h 34, 1944 Yonge MO 4449 — Ronald asst suprvsr CPR h 7 Gamble av (E Y) RI 1575 — Rubert G paper handler Star h 10 Northvlew av (Scar) OX 3964 — Thos motor mech Property Dept h 43 St David — Vange elk S S Kresge r 233 Ashworth av LO 7870 — Wm ftr John T Hepburn Ltd r 663 Dovercourt rd — Wm sec-treas C A Parsons of Canada Ltd res Port Credit — Wm CRlcPOh45 Cotton av (Scar) —Winifred (wld H G) h 11 St Hilda’s av HU 9-7709 Barrleau Sylvaln emp Can Bread h 181 Hallam KE 2932 Barrlerl Fred wtr Royal York Hotel r 90 Sydenham Barries Gerald h 768 Queen e Barriger Lellah Mrs opr J D Carrier Shoe h 61 Rusholme Park cres Barringer John F drvr Clover Taxi Co r 21 Douglas av HU 8-5134 — Mary E r 212, 2928 Yonge HU 8-8895 — Mildred E (wld Wm) h 21 Douglas av HU 8-5134 — Wm H purch agt Chateau-Gal Wines h 117 EUerslle av (WlUowdale) Barrlngham Dorothy A (wid Arthur B) h 34 Westchester rd (Nth Y) CH 1-0188 — Harold slsmn Prudential Ins r 307 Wilson Hts blvd (Nth Y) — Rubber Plastics Ltd G R Bellinger K B MacLaren reps 183 Front e EM 8- 1141 Barrington A Josephine r 40 St Leonards av MA 3904 — Edwin G with Tor Hydro h 293 Durie LY 5177 — Elsie I tchr Runnymede Pub Schl r 293 Durie LY 5177 — G Edwd (J W Barrington Son) h 48 Fairfield rd (Nth Y) MA 5472 — Ida tchr Genl Mercer Davenport Rd SclU r W Hlllcrest dr KE 8006 --J W Son (G Edwd Barrington) leather goods saddlery mfr import 75-75A Adelaide w EM 4- 8795 —John R factory foremn Dearborn Chem r 810 Mt Pleasant rd MO 3392 — Joseph emp Drlve-ln Cleaners h 78 Ivy av HA 7158 — Joseph W with J W Barrington Son h 40 St Leonards av MA 3904 — Murray G with Can Packers r 293 Durie LY 5177 — Norman F elk Gutta Percha r 34 Greenlaw av OL 3498 — Robt J furrier Manufacturers Fur Sis h 370 Brooke av (Nth Y) RE 0859 — Ronald E studt r 293 Durie LY 5177 — Ross C tchr Central Tech Schl h 84 Hlllcrest dr KE 8006 — Smoke Shop (Alex Segal) 2588 Danforth av
- 38. GR 7422 —Thos studt r 84 HUlcrest dr KE 8006 —V E Mrs h 501, 2837 Yonge HU 9-5584 — Wm A h 127 Felbrlgg av OJth Y) RE 2033 — Wm B emp CGE r 22 Silver Birch av Harris Alex reporter Globe Mall r 46 Bethune blvd (Scar) — Bernle r 80 Shelborne av (Nth Y) OR 0775 — Irwin plmbr stmftr h 351 Markham RA 6998 —Sam h 80 Shelborne av (Nth Y) OR 0775 Barrlsdale Frances r 52 Westmoreland av LO 7772 Barrlskell Wm r 30 Keewatln av Barristlcky Harry emp H Elsen Bag Co r 171 Huron Barritt Fredk W litho Conti Can r 23 Eldon (E Y) BARRITT — Thos W janitor Donlands Dairy h 195^ Woodvllle av (E Y) RI 3051 Barron A L r 47 Manor rd e MA 4253 — Adella (wld Ludwlk) h 435 Lansdowne av LO 6800 —Alex with Tor Hydro h 1099 Davenport rd LL 544? — Alex E (Fry Co) h 14 Apsley av (Nth Y) HU 9-9988 --Alex R heavy equip opr Dept St Clng h 60 Chisholm av GR 1544 —Alfred h 64 Enfield av (Etob) — Alice M r 317 HUlsdale av e HU 9-6091 —Alma M (wld Arthur) mgr’ss Taylor’s Service Stores (1946 Danforth av) h 92 Monarch Pk av HA 6267 —Annie B (wld Robt T) h 9 Greensldes av LO 6118 — Armeda r 8 Forest Wood (Nth Y) — Arthur emp Moore Barran r 40 Orrell av (Etob) BE 1-8613 — Bert A mech Can Coal Co h 28 LUllngton av (Scar) HO 2620 — Charlotte L elk TTC r 9 Greensldes av LO 6118 — Christina (wld Chas) h 35 Enderby rd OX 9233 — Christine (wld Alex) r 19 Enfield av (Etob) — Colin turnkey Toronto Jail h 1103^ Davenport rd LA 6932 — D’Alton emp Gray Forgings Stampings Ltd r 66 Teignmouth av (York Twp) LA 5200 — David radio insp r 178 Mortimer av (E Y) GE 6693 — David A carp Bank of Mont h 7 Hlghcllff cres (Scar) — Dennis p c Police Dept r 1 Briarcroft av — Donald W acet Carswell Co h 125 Melrose av HU 9-9582 — Doris I stenog TTC r 15 Clarendon av RA 3307 — Dwight emp Glldden Paint Co h 59 Melville av KE 0112 — Earl plstr r 608 Greenwood av HA 7431 -»-Earl R carp h 183 Close av LA 0185 — Edwd (City Salvage) h 206, 1654 Bathurst (York Twp) RE 5961 --Effle r 8 Edna av LL 3071 — Eleanor plshr Eatons r 35 Enderby rd OX 9233 — Elinor prlv sec Candn Chromalox r 11 Hurstlngs av (York Twp) LL 2564 — Elizth nurse Lever Bros r 203B Sheldrake blvd MO 5536 —Elizth off staff H J Heinz r 301 Main n (Wstn) CHl-2500 --Elsie M off sec Ideal Stoker Co h 207, 1233 Yonge KI 8112 — Eva h 608 Greenwood av HA 7431
- 39. — Francis r 47 Norval (York Twp) LY 8898 — Francis J slsmn Gas Co r 212 Chambers av (York Twp) MU 7195 — Frank caretkr Franklins’ h 212 Chambers av (York Twp) MU 7195 — Frank real estate broker h 712 Sammon av (E Y) HO 6221 -^Frank J h 86 Waverley rd HO 9066 — Fred drvr Longworth Milling h 2072 St Clair av w LY 0007 — Fred A ydmn Lake Slmcoe Ice r 19 Pembroke — Gay sis elk Eatons r 8 Forest Wood (Nth Y) — Gfeo A public relations CGE r 118 Robina av (York Twp) OR 7547 — Geo B drvr slsmn Sllverwoods r 25 Douglas dr (Etob) — Geo W stablemn Sllverwoods h 118 Robina av (York Twp) OR 7547 — Gerald emp Stand Sanitary r 144 SeUers av — Harold H h 2 Parr LO 3464 — Harry emp Tip Top TaUors h 388 Roxton rd ME 2504 — Harry pres Harry D Reid Agencies Ltd h 209 Rosedale Hts dr MO 8590 — Harry L slsmn Theatre Posters h 18 Highbourne rd HU 9-0423 — Harvey C elk Travlss Hardware r 92 Monarch Park av HA 6267 --Helen r 379 Rusholme rd LA 5513 — Henry contr r 98 Mountview av LY 9006 ' — Herbt elk C P Exp r 178 Mortimer av (E Y) GE 6693 — Howard mech Hogan Pontiac Buick res Aglncourt — Ian emp DeHavilland Aircraft r 100 Branstone rd (York Twp) OR 3827 -■-Irene K Mrs elk Dept of Agric (Ont) r 1749 Avenue rd n (Nth Y) --J Alex elk Royal Bank h 102 Cadorna av (E Y) HA 7767 — J Bruce slsmn Alloy Metal Sales h 303 Bessborough dr (Leas) MA 4229 --J Christopher elk Cassels, Blalkie Co r 19 Poplar Plains cres MI 2625 — Jas r 482 Glenholme av (York Twp) —Jas r 167 Symons (Mlm) — Jas ctr TugweU’s h 47 Norval (York Twp) LY 8898 — Jas malnt man Hollinger Bus Lines h 75 Redwood av HA 1422 — Janet r 331 Sherbourne — Jean (wid Wm) r 427 Mortimer av (E Y) GE 0171 --Joan F advertising Ruthrauff Ryan r 183 Close av — John r 11 Centre av — John r (rear) 123 Dundas w EM 3-9831 — John h 178 Mortimer av (E Y) GE 6693 — John (Numbering Machine Co) h B9, 608 Church KI 4230 — John sis elk Edward’s Hardware r 47 William Cragg dr — John A sec mgr Insurance Institute of Ontario h 19 Poplar Plains cres MI 2625 — John G bkr P,asmussen h 100 Branstone rd (York Twp) OR 3827 — John J acet Ont Hydro h 22 Glenbrae av (Leas) MA 2537 — John O elk P O h 59 Abbott av JU 6334 — John W' tractor drvr Sllverwoods h 19 Enfield av (Etob) — Joseph emp Sllverwoods r 725 Manning av OL 4133 --Joseph order
- 40. filler Cochrane-Dunlop Hardware r 445 Vaughan rd (York Twp) ME 6140 --Lila M r 47 Norval (York Twp) LY 8898 — Mabel (wld Fredk) h 609 Caledonia rd (York Twp) — Madele D elk Mnfrs Life r 639 Milverton blvd —Margt opr Flash Fasteners r 19 Enfield av (Etob) — Margt P C B C Mrs typist Ont Hosp Assn Blue Cross h 588A Mt Pleasant rd MO 8163 — Marjorie assmblr Dom Watch Case r 1103i Davenport rd LA 6932 — Marsden D elk Bank of N S h 33 Duggan av HU 9-1569 — Mary Customs Excise r 138 Westminster av LL 6085 — Mary stenog CNR Customs r 105 Bernard av PR 3267 — Mary A elk Dom Bank r 47 Manor rd e — Mary A emp J C Adams Auto Accessories r 1099 Davenport rd LL 54 49 BARRON — Mary A E Mrs elk Bank of Mont r 41 Duggan av — Maurice I cook CPR h 31 Wlnnlfred av HA 3257 —Max h 260 Major KI 9209 —Merle P stenog- typlst Star r 7 Thomwood rd — Michael r 175 Manning av EM 4-4546 — Michael caretaker Health League of Canada h (rear) 111 Avenue rd PR 3083 — Michael pipe coverer Vlnoent-Cutler Insulation r 185 Nairn av --Michael pipe insiUator r 144 SeUers av (York Twp) LL 5963 — Murray elk Eatons r 82 Grandview av (Newtonbrook) — Norman ydmn CPR h 547 Jane (York Twp) LY 5125 — Norman D make up man Globe Mail h 639 Milverton blvd QX 5305 — Percey slsmn r 379 Rusholme rd LA 5513 —Rlchd r 149 St George MI 5185 — Robt carp Dept of Wks h 76 Beachvlew cres HO 3437 — Robt phy h 209 Glen rd RA 8553 — Rodney S engineer Moloney Elect r 64 Enfield av (Etob) — Stephannie Mrs drsmkr Eatons r 978 Greenwood avenue — Sydney A bus drvr TTC h 26 Horsham av (WlUowdale) — Verna Mrs r 156 Heath e HU 8-2609 — Wm h 301 Main n (Wstn) CH 1-2500 — Wm D carp h 241 Keele JU 6729 — Wm H h 157 HUlhurst blvd MA 4019 — Wm H with Natl Trust h 75 Maepherson av RA 1630 — Wm R mach Bowden Machine r 47 Norval (York Twp) LY 8898 — Wm S carp TTC h 260 Chisholm av (E Y) OX 1405 — Winston H publicity dir Paramount Film Serv h 8 Forest Wood (Nth Y) OR 6106 Barrons Agnes Mrs r 319 Inglewood dr HU 9-4912 — David r 369 Keewatln av — Elmer W mgr S J Brooks Co h 60 Glen Echo rd HU 9-4178 — Henrietta Mrs r 328 Brunswick av MI 0048 Barros David S elk Singer Sewing Mach r 229 Steele av e (Nth Y) Barrow Albt h 1135 Greenwood av (E Y) HA 6829 — Albt pntr dec E C Denney r
- 41. 773A Annette JU 2764 — Alice (wid Wm) h 343 Davlsvllle av HU 9- 9241 — Barbara A nurse Upper Can Coll r same HU 9-1581 — Benj H (Barrow Music Supplies) res Westhlll —Bud ©ud’s Barber Shop) h 1352 Weston rd (York Twp) JU 7770 — Caroline (wid Noel) h 59 Humber Trail (York Twp) JU 9756 — Chas trk drvr r 530 Church — Clive office boy Aluminum Co r 1, Unit 7, Lansing Court Apts (Lansing) — Cyril (Barrow Signs) r 563 Mt Pleasant rd —Edwd W h 506 Royal York rd s (Etob) --Elgin T slsmn Genl Foods res Richmond HUl — Elsie M nurse r 1892 Gerrard e — Frank plmbr r 18 Gardens cres (E Y) OX 8860 — Gladys (wid Gore) r 8 Cawthrasq RA 7239 — Graeme A office boy Dept of Highways (Prov) r 1, Unit 7, LanSing Ct Apts (Lansing) — Joan prlv sec r 80 Spencer av LA 3420 — John r 67 Isabella KI 9391 —John h 192 Langley av HA 3514 --John C asst merchandise mgr Simpsons h 248 Glenview av — John E emp Wlckmans Steel r 506 Royal York rd s (Etob) —John H h 506 Royal York rd s (Etob) —John M sis dept Ferranti Elect h 47 Boyd av (Wstn) CH 1-6714 — John T emp O’Keefe’s h 223 Seaton RA 2717 — June P r 59 Humber Trail (York Twp) JU 9756 — Louise h 306 , 45 Lorindale av MA 4132 --Mildred elk Tor Stock Exchange r 103 Heward av GE 8671 — Music Supplies (Benj H Barrow) music supplies 2nd fir, 365 Yonge EM 4-5651 — Phyllis tchr John Ross Robertson Schl r 343 Davlsvllle av HU 9-9241 —Regd H musician h 612 Broadway av (Leas) MA 6088 —Rex mech Frigidaire Products r 19 Field av (Leas) MA 7397 — Rlchd h 4 Nassau pi EM 6-1574 — Robt r 95 Lappin av LO 7752 — Robt assmblr L C Smith r 26 Yarmouth gdns — Robt electrotsrper Diver Electro h 123 Alfred av (Lansing) — Robt opr Aluminum Goods Ltd h 9^ Lappin av LO 7752 —Robt G h 34 Humbervale blvd (Etob) CE 1-1674 — Rosalynd V stenog Imp OU r 59 Humber Trail (York Twp) JU 9756 — Roy J druggist Tor Genl Hosp r 506 Royal York rd s (Etob) —Sarah h 23 Everett cres (E Y) GR 7757 — Signs (Cyril Barrow) 12 Keewatln av HU 9-7482 — Sydney meat mgr Loblaws h 16 Gair dr (Etob) — T rly mail elk P O r 27 Drury av (Thornhill) --Terry emp Gardner Textile Machinery Co r 256 Lisgar — Thos L ink mixer Fredk L Levey Co Ltd h 1892 Gerrard e — Viola emp Natl Theatres r 4, 350 Oakwood av (York Twp) RU 1-0891 — Wm A lab Dept St Clng r 85 Coleman av Barroweliffe Fred K malnt U
- 42. of T h 220 Fairview av RO 1401 — Norman A elk Unemployment Ins Commn r 220 Fairview av RO 1401 Barrowclough Volney R purch agt Mine Safety Appliances h 69 Appleton av (York Twp) OL 3260 — Wm H emp CNR h 34 Little blvd (York Twp) OR 3330 Barrowman Allan (Monarch Pattern Works) h 22 New Haven dr (Fst H) MO 5152 — Art, The (Jas Barrowman) artists supplies gifts 490 Bloor w ME 4961 — Gordon emp Ont Hydro r 187 Pearson av LO 0660 — Harry G emp Liquor Control Bd of Ont h 68 Pricefield rd MI 1310 — Jas (The Barrowman Art) res Freeman — Jane (wid Robt) r 68 Pricefield rd MI 1310 — Margt Mrs emp Regal Stationery r 187 Pearson av LO 0660 —Sydney E stkpr Simpsons h 27 Eastmount av GE 2134 Barrows Betty r 6 Willingdon blvd (Etob) CE 1-0740 —Mary h 6 Willingdon blvd (Etob) CE 1-0740 Barrs Fred A foremn of prntrs Candn Wallpaper Reg N Bov-er Div h 52 Superior av (Mlm) — Margt Mrs r 12 Columbine av OX 2550 — Marilyn dental asst Harvey Jenkins r 4, 172 Vaughan rd (York Twp) RE 6098 —78
- 43. BARRUCH Barruch Edith S sec-treas 1 H Barruch Ltd r 23 Westgrove cres (Nth Y) HU 8-7739 --J H Ltd Jacques H Barruch pres, Sam L Kagan vice-pres, Edith S Barruch sec-treas infants children’s wear 214 Main OX 1129 --Jacques H pres J H Barruch Ltd h 23 Westgrove cres (Nth Y) HU 8-7739 Barry Agnes M off mgrss Dickson, Jolliffe Co r 9 Baby Point rd (York Twp) —Alan J C studt r 136 Moore av HU 9-5480 --Alex elk Bright’s Wines Ltd h 1 Squires av (E Y) OX 5832 —Alex J elect Arcade Electric h 34 Chudleigh rd (York Twp) RU 1-0655 —Alfred carmn CNR r 8 Marigold av GL 5802 -- Alfred printing prsmn Litho-Print h 25 Doel av GL 0655 —Ann Mrs lunch rm attdt U S Fidelity Guaranty h 34 Benson av LA 0897 — Ann R mgrss Woman’s B^ery Ltd (413 Spadina rd) r 385 Spadina rd — Anne bkpr St Michael’s Hosp h 52, 122 Dowling av LL 5664 — Arnold R drftsmn Hanks Irwin r 17 Cowley — Arnott dairymn Borden Co h 206 Livingstone av (York Twp) —Arthur r 23 Norfolk LO 2550 — Arthur emp O’Keefe’s Brewery r 295 Church EM 8-1544 -- Arthur mech Marshall Refrigeration Co r 153 Simpson — Barbara (wld John) h 202 Earlscourt av LL 6448 --Betty stenog B A Oil r 100 Poplar Plains rd MI 1903 --Borden transp drvr Roselawn Dairy h 691 Brock av LO 2686 --Bruce D elect CPR h 145 Mavety JU 3798 — Bruce J service correspondent MinneapolisHoneyweU h 50 Wallace av LL 6174 — Cecil E (Bayvlew Hardware) h 544 Bayview av (Leas) HU 9-7900 — Claire emp TCA h 14F, 445 Lake Shore rd (Mlm) — Cornelius emp Genl Steel Wares h 717 Carlaw av HA 9846 — D asst caretkr Roden Pub Schl r 478 Main — Danl J property valuator Dept of Highways (Prov) h 31 Inglewood dr HU 9-2886 — Daphne typist Dom Fire Ins r 46 Gwynne av --David shpr MacLaren Wright h 108 Sellers av LA 4996 --David J prsmn Daily Racing Form h 629 Ontario MI 6471 — Donald G drftsmn Shell Oil h A, 7 Anglesey blvd (Etob) CE 1-2339 — Dorothy nurse r 237 High Park av JU 3027 — Dorothy Mrs nurse Queen Elizabeth Hosp r 68 Dunn av LA 7472 --Dwain emp John Inglis h 35 Haslett av HO 1546 — E emp Nicholson’s r 41 Holley av (Wstn) CH 1-1444 — Edith A Mrs elk Genl Accident Assce r 448 Lauder av (York Twp) RE 0531 --Edith M (wid Fredk C) h 136 Moore av HU 9-5480 — Edmund emp C N Exp r 9 Brooklyn av GL 5172 —
- 44. Edwd emp Pickering Farms r 276 Oriole Pkwy MA 7277 — Edwd lab r 1 Alpha av RA 7038 — Elenor elk Bank of Com r 34 Benson av — Elizth off elk Eatons r 162 First av GE 7443 — Ernest lab techn Imp Varnish r 844A Bloor w — Ernest ydmn S McCord Co Ltd r 580 Parliament — Flora parlour maid r 3 Cluny dr RA 1059 —Florence Mrs r 265 Forest HIU rd (Fst H) RE 7924 — Frank J asst genl mgr John B Smith Sons h 35 Glenavy av (Nth Y) — Frank J accounting elk Underwood Mfg h 1, 1044 College OL 2157 — Fred lab Dept of City Planning r 8 Marigold av GL 5802 --Fred J maint Business Systems h 712 Rhodes av HA 4106 —Fred W emp Parks Commn h 162 First av GE 7443 —Fredk J h 60 Follis av LA 9859 — Fredk V drvr slsmn Sllverwoods h 385 Spadina rd (Fst H) MA 3085 —Fredk W stkpr Thos J Llpton r 162 First av GE 7443 — Geo p c East York Twp h 217 Ferris rd (E Y) OX 5503 — Geo P mech Massey-Harrls h 2, 343 Pape av HA 4856 — Gerald foremn Warehouse Metals Ltd r 2, 553 Bloor w --Gerald J frt elk CPR h 473 Strathmore blvd OX 2843 -- Gertrude emp Sinnot News Co r 44 Marina av (Long B) — Grace (wid Peter) r 1194 Queen w LO 0357 —Grace B h 315, 45 St Clair av w MI 2042 — Guy C emp Prest-O-Light r 427 Salem av LO 1245 -- Harold suprvsr signs bldg permits Dept of Highways (prov) h 692 Oriole Pkwy HU 8-2548 — Harold A officeman The Foundation Co of Ont Ltd h 740 Woburn av (Nth Y) RE 4760 — Helen emp Aluminum Co of Can h lOG, 447 Lake Shore rd (Mim) — Helen hsekpr Corpus Christie (R C) Church r 16 Lockwood rd HO 7756 — Helen tchr Roden Pub Schl r 486 Summon av — Ida J h 315, 45 St Clair av w MI 2042 —Irene r 29 Bernard av RA 0332 — Iris G elk Rolph-Clark- Stone r 2061 Gerrard e OX 4954 --Jack elect Tor Hydro r 63 Winchester RA 6083 —Jack racker Prest-O-Llte r 427 Salem av — Jas h 108 Boon av --Jas h 270i Wellesley e --Jas E h 49 Kingston rd HO 8011 —John h 187 Perth av KE 5124 --John r 18 Wilmot av — John asst shpr Bromo-Seltzer r 158 Woodmount av (E Y) OX 0975 — John emp Simpsons h 309 Gowan av (E Y) --John opr TTC r 51 Lansdowne av --John plumbing heating contr 486 Sammon av (E Y) GE 6274 h same --John A pntr K Fraser h 100 Poplar Plains rd MI 1903 --John F Clk of the Peace Office h 197 Perth av LL 3704 --John G wrehsemn Rosco Metal r 41 Commonwealth av — John J emp City
- 45. Parks Dept h 8 Marigold av GL 5802 --John J orderly Tor Western Hosp h 82 Ferrier av GL 8266 — John O elk P O h 108 Cumberland — John S slsmn Ont Automobile h 109 Marjory av GL 3117 — Joseph emp Dunlop Tire h 236 Woodmount av (E Y) OX 6186 --Joseph ftr Gas Co r 770 Shaw BARRY —Kathleen opr Parker Pen h A25, 9 Tennis cres RI 1545 — Kenneth T 1 c P O h 349 Glebeholme blvd — Lauren trav Can Packers r 33 Burnfield av LO 4019 — Leo J C genl elk C P Exp h 37 Farnham av — Loretta N sec Edwd A Morgan Arthur Cole h 48 Sussex av KI 0966 —Mabel Mrs tchr Birch Cliff Hts Pub Schl res Oshawa — Mabel A elk Glidden Faint h 196 Humbercrest blvd (York Twp) MU 2346 — Maisle I graphic card fnshr Rolph-Clark-Stone r 2061 Gerrard e OX 4954 — Malvina (wld Wm) h 487 Broadview av GL 1309 — Mfg Co (Wm McConaghle Fern McCullough) plastic products 9 Dwight av (Mim) RO 2293, --Margt emp Rowntree Co r 1153 College --Margt emp Slnnott News Co r 44 Marina av (Long B) — Margt Mrs nurse Queen Elizabeth Hosp h 123^ Dunn av OL 3040 —Marjorie Mrs h 4 Gowan av (E Y) GE 6793 --Martha Mrs h 159 Madison av —Mary Investigator Eatons r 1079 Queen w --Mary E swtchbd opr Bank of Tor r 226 Pearson av LA 1683 — Miriam swtlchbd opr Brewers Retail r 9 Brooklyn av GL 5172 —Murray cartage agt h 116 Brookside dr — Murray emp Campbell Cartage Co r 394 Wellesley e MI 8291 —Nancy r 449 Sammon av (E Y) HA 8356 —Norman C emp O’Keefe’s r 1194 Queen w --Norman E with Tor Hydro h 49 Kingston rd HO 8011 — Otta (wid O R) r 196 Humbercrest blvd (York Twp) MU 2346 —Patrick emp Consolidated Press h 135 Tecumseth EM 4-2940 — Patrick mech Gault Elevator Co h 122 Langley av HA 4244 --Patrick A h 82 Thirty-First (Long B) — Paul M stk trader Gairdner Co r 19 Goodwood av KE 5917 — Phillip h B, 402A Queen e — R W shpr Christie’s Bread r 122 Wheeler av -- Ray H suprvsr Natl Life Assce h 84 Wellesley e RA 0369 —Raymond A installation dept Northern Electric h 7 Beaufleld av (Leas) — Rlchd G asst acet Dom Bank r 62 Bogart av (Lansing) — Robl r 43 EUerbeck GE 8480 — Robt slsmn Century Television h 2 Larchmount av GE 8169 — Robt J mach Gair Co h 196 Carlaw av GL 9868 — Robt J repalrmn TTC h 9 Brooklyn av GL 5172 --Roderick W assmblr Christie’s Bread r 122 Spruce HiU rd — Ronald drvr Eatons h 478
- 46. Main (E Y) — Rose (wid Joseph) h 44 Marina av (Long B) — Rose (wid Micteel) h 19 Goodwood avKE 5917 — Ruby hrdrssr Steam’s Beauty Salon r 33 Burnfield av LO 4019 — Ruth F interviewer Workmen’s Compensation Bd r 2 Dault rd (Scar) OX 0823 — Sadie bkbndr press feeder Windsor Press r 1231 Bathurst LA 1746 — Sadie hsekpr r 1680 Dundas w ME 8188 — Thelma r 21 Widmer — Velma Mrs r 70 Cameron — Vera B stenog B A Oil r 100 Poplar Plains rd —Victor S trk drvr Sun Oil r 196 Carlaw av GL 9868 — Vincent G prospector r 18 Temple av LA 6532 — Vincent P elk CNR h 50 Wallace av LL 6174 — W Leonard h 394 Wellesley e MI 8291 — Whitney frt handler CPR h 11 Wyatt av — Wilfred asst mgr Liquor Control Store #11 h 136 Sutherland dr (Leas) HU 8-8539 — Wm h 844A Bloor w — Wm emp Bank of Mont h 16 Fern av (Wstn) CH 1- 1708 — Wm motormn C N Exp r 225 Gladstone av — Wm E drvr Stone Cartage h 138 Wheeler av — Wm I mach opr CCM r 41 Holley av (Wstn) CH 1-1444 ■ — Wm J trader Frank S Leslie Co h 36 Pearson av LL 9822 — Staines Linoleum (Canada) Ltd Jas-D Gerrard mgr linoleum mfrs 902, 21 Dundas sq EM 8-3343 Barry’s Hardware (Alex Howitt A T Parker) 3095 Dundas w LY 0076 -- Men’s Wear (Barry Blitsteln) 765 Lake Shore rd (New T) Barrymore Arms Apts 2 Salem av BARRYMORE CLOTH COMPANY LIMITED, Barry B Hayes President and General Manager, C W Hayes Vice- President, W G Berner Secretary-Treasurer, 1179-1189 King West, Phone LAkeslde 3321 — Furniture Co (subsidiary of Toronto Carpet Mfg Co Ltd) 1137 King w LA 2891 Bars John fruit mgr Power Stores h 35 Chlcora av RA 3630 — Krestaps h 35 Chlcora av RA 3630 — Vladislav r 35 Chicora av RA 3630 Barselaar Arie supt Brighton Apts h B2, 97 Avenue rd PR 1891 Barsh Louis barber 433 Spadina av KI 1890 r 46 Bedford rd — Sam (Reliable Auto Body) r 84 Ridgevale dr (Nth Y) Barshay Fay (wid Aaron) h 94 Burnside dr ME 0892 — Gerl sec Joseph A Cosentlno r 94 Burnside dr Barshewski Irene elk A P r 1237 College LA 8998 —Julia emp Crafts Sportswear h 1237 College LA 8998 --Steven tlr r 208 St Clarens av Barshtz Benj (Hub BlUlard Parlour) h 305 Spadina av EM 3-1659 —Jacob h 157 Baldwin EM 6-1347 Barsketls John mach opr Easy Washing Mach h 70 Scott rd (York Twp) JU 6248 — Motejus hlpr S H Newman Co h 21
- 47. Sorauren av LA 7134 Barskutls Stanley kitchen hlpr Tor Western Hosp r 26 Wascana av TR 1419 Barsky Annie r 28 Braemar av MO 8962 — Harry telegrapher C N Tel h C, 711 Bloor w — Morris (Ontario Chesterfield Co) h 21 Glen Cedar rd (York Twp) OR 2085 — Philip (Ontario Chesterfield Co) h 193 Lonsmount dr (Fst H) LO 1268 Barsley Annie (wid John) r 186 Rushton rd OL 4575 — Nita elk Crown Life Ins r 711 Bloor w — Roy aircraft insp A V Roe h 44 Fatika av (Wstn) CH 1-2769 Barsness Clifford brusher Frlgidalre Products r 158 Dawes rd (E Y) BARSON Barson Albt stkpr Genl Prntg Ink h 186 Gilbert av (York Twp) KE 1796 — Allan G maint Union Station h 6, 235 Vaughan rd (York Twp) RU 1-0209 Barsotta Frank instailler Northern Electric h 38 Rhydwen av (Scar) OX 7624 — Gordon h 47 Wroxeter av HA 1581 Barsottl Harold shpr United Steel h 27 Northcote av ME 6771 Barsottle Eleanor Invoice elk Eatons h 60 Symington av LA 6903 —Geo r 13 Atkin av LA 7977 —Regan engineer Dept Property h 13 Atkin av LA 7977 Barss Geo W machine shop foremn Gair Co h 247 Blcknell av (York Twp) LY 6517 —Robt G suprvsr Eatons h 110 Esgore dr (Nth Y) MA 3927 Barstead Arthur R elk P O h 98 Oakvale av GE 0860 —Olga (wid Benj) h 1797 Dufferln KE 2719 Barstow Cecilia hsekpr r 2463 Danforth av GR 9988 -- Gordon mech h 192 Dlvadale dr (Leas) HU 94257 --John M emp Mathers Haldenby h 1, 538 Sherbourne PR 3459 — Percy r 2720 Danforth av Barsvarl Nicholas glass wkr Fllklngton Bros Can Ltd h 426 Osslngton av Barsys Alfreda r 284 Crawford LA 2114 Bart Isabelle H stewardess TCA r 205 Springdale blvd (E Y) RI 6028 — Jim (Jim’s Grill) h 594 Queen w — Joseph millwright Wedlock Paper Bag h 205 Springdale blvd (E Y) RI 6028 — Leonard J ins adjuster Genl Motors r 205 Springdale blvd (E Y) RI 6028 Barta Julius r 73 Prince Arthur av KI 0536 Bartal Konsta emp Gair Co h 193 Willow av GR 7698 Bartalos Stephen btehr Can Packers h 50 McRoberts av KE 6690 Bartanus Wm tool mkr Reliable Toy Co h 51 Parkdale rd OL 4693 Barteaux Owen C underwriter Employers Liability Assce Corp h 25 Larkin av (Swan) LY 7308 Bartek Geo r 135 Manning av EM 4- 4619 Bartel Arnold prsr h 43 Robina av (York Twp) LA 0110 --Arthur studt r 43 Robina av (York Twp) LA 0110 —Elgin credit auditor Genl Motors r 19 Ronald av (York Twp) — Mary r 35 Brunswick av MI
- 48. 6211 — Olga r 43 Robina av LA 0110 Bartelettie Artillio brklyr r 66 Caledonia rd Bartell Arthur mgr United Tool Die Wks h 634 Bedford Fk av (Nth Y) OR 9545 — Mildred Mrs mach opr Rose Marx r 139 Margueretta OL 1715 — Thos r 26 Homewood av — Victor F excise tax auditor h 519 Old Orchard gr (Nth Y) RU 1-0874 — Wm emp Sunnybrook Hosp r 46 Lamb av GL 6172 Bartella Sami emp Can Packers r 693 Durle (York Twp) MU 7047 Bartello Andrew r 600 Markham KE 8740 --Angelina Indry press opr Royal York Hotel r 327 Manning av . — Angello (Glenlake Market) h 204 Howland av ME 9547 — Carmen lab h 600 Markham KE 8740 —Catharine r 600 Markham KE 8740 — Chas prntr h 600 Markham KE 8740 — Frank (Frank’s Cleaners) h 31 Fuller av ME 2595 — Frank A emp Dom Radiator r 64 Carus av LA 9016 — Irene studt r 1558A Bloor w — John core mounter Stand Saniatry h 64 Carus av LA 9016 — John plstr h 1325 Dapont LA 0813 — Joseph engineer CPR h 289 College KI 1866 — Joseph V contr h 436 Armadale av MU 5525 — Marjorie (wid Jas V) (Glenlake Market) r 919 Manning av ME 8710 — Mary (wid John) h 30 Ford JU 0751 — Mildred hrdrssr Paramount Hairdressing r 361A Clinton ME 1045 — Peter br mgr North American Life Assce Co r 33 Lynn Haven rd (Nth Y) —Ralph M wksmn W W Wells h 1558A Bloor w LL 3857 — Rose (wid Antonio) h 36I5 Clinton ME 1045 — Thos emp Swansea Construction h 77 Vernon MU 5216 — Vincent emp Tip Top Tailors r 64 Carus av LA 9016 — Wm F statistics elk Addisons Ltd h 45 Arrowsmith av (Nth Y) Bartels Oscar C investment counsellor 309-310, 100 Adelaide w EM 8-3561 h 61 Highland • av RA 9358 — Oscar V r 90 Dunloe rd (Fst H) MO 1226 Barten Harry brklyr h 244 Major — Michael drftsmn Eatons h 136 Cheltenham av (Nth Y) MO 7066 Barter Alex mach tender Disher Steel h 785 Sammon av (E Y) — Alfred L city flremn h 40 Neilson av — Alice (wid Fred) h 688 Lansdowne av OL 1335 --Chas W bus drvr TTC h 29 Haslett av OX 6405 --Dorothy filler Eatons r 97 Perth av KE 4034 — Dorothy press-feeder Candn Bag r 688 Lansdowne av OL 1335 — Ernest J rep Superior Brush Mfg Co r 48 Yorkmlnster rd (Willowdale) — Frances Mrs r 84 Maepherson av RA 5317 — Francis D elk Inti Bus Mach r 219 Glendora av (Willowdale) — G B Motors Limited G B Barter pres, Evan R Peacock vice-pres, N Smith sec
- 49. automobile dlrs 54 Lake Shore rd (Mim) — Gerald B pres G B Barter Motors Limited h 3005 Bloor (Etob) CE 1-2236 — Gladys emp Candn Wirebound Boxes r 103 Madison av KI 9493 — Herbt M drftsmn CNR h 395 Willard av JU 4372 — Jas emp Texaco Oil Co h 79 Morse HA 7083 — John C pastry cook Royal York Hotel r 29 Haslett av OX 6405 —Jonas specialty mgr Candn Food Prod h 51 Oriole Pkwy MO 4607 — Myra elk North Amer Life r 785 Sammon av (E Y) — W J pres W J Barter Motor Sales Ltd r 745 Scarlett rd (Wstn) — W J Motor Sales Ltd W J Barter pres, Alex Lippay vice-pres, L H Rowntree sec 9 Lawrence av w (Wstn) CH 1-5283-4 — Wm cook The Old Mill h 97 Perth av KE 4034 Barterer Wm setter S Fremes Co r 209 Howland avenue Bartesch Harry lab Stand Sanitary r 26 Draper av Barth Alice Mrs h 111 Bingham av OX 5791 — Benj sec-treas Barth Son Furs Ltd h 13 Heathdale rd (York Two) RE 7816 BAR BARTKUS BARTH — Doris K emp Simpsons r 221 Melrose av HU 8-2598 — Frank r 2161 Dundas w LO 7510 — Fredk shpr Scythes Co h 126 Campbell av LA 2689 — Harold R (Barth’s Drug Store) h 1392 Weston rd (York Twp) LY 2625 — Jacob emp John Inglis h 285 Jones av GL 6600 — John J sausage mkr Quality Meat Packers h 602 Concord av LL 7232 — Kurt wldr Monarch Welding r 105 Essex ME 5388 — Leslie H slsmn White Stationers h 56 Beachview cres OX 3558 — M lab Labatts h 61 Jedburgh rd HU 8-9593 — Marion buyer Simpsons r 221 Melrose av HU 8-2598 — Max pres Barth Son Furs Ltd h 53 HUlcrest dr LL 8314 — Peter h 170 Montrose av OL 4803 — Philip (Central One Hour Cleaners) h 239 Joicey blvd (Nth Y) HU 8-5279 — Tony caretkr Beth Tzedec Synagogue h 403 University av EM 6-8889 — Wm emp Scythes Co r 126 Campbell av LA 2689 — Wm paperhanger pntr W R Motherslll h 252 Llnnsmore cres (E Y) GE 1414 — Wm sec-treas E H Ashley Co (Can) Ltd h 120, 1996 Bathurst (York Twp) — Wm W heating contr h 483 Broadview av RI 0033 — Winifred (wld Geo) h 221 Melrose av HU 8-2598 — Son Furs Ltd Max Barth pres, Annie Barth vice-pres, Ben Barth sec-treas mfg furriers 3rd fir, 317- 321 Adelaide aw EM 4-8534 Barth’s Drug Store (Harold R Barth) 1392 Weston rd (York Twp) LY 2625 Bartha Joseph (Paris Garments) h 1, 76 Harbord KI 5838 Barthau Lloyd D wtchmkr Ostrander’s Danforth h 18 Dalecrest dr (E Y) HO 3478 — Muriel H stenog Atlantic
- 50. Service r 108 Riverdale av HA 4131 — Norma G payroU elk Imp Oil r 221 Glebeholme blvd HA 1598 — Wm L steel stamps 207A Church EM 3-2881 h 221 Glebeholme blvd HA 1598 Barthay Muriel H priv sec Atlantic Serv r 108 Riverdale av Barthe C Ernest r 129, 22 St Thomas RA 5141 — E Victor mgr Prudential Trust r 40 Browning av GE 3844 Barthelmels Marie h 122 Balmoral av MI 8094 Barthelmes Apts 464 Spadina rd (Fst H) — Cecil F serv mgr Sheridan Equip h 125 Bessborough dr (Leas) MO 2552 — Edwd C emp CPR h 39, 210 Wychwood av (York Twp) ME 8276 —Harry F r 125 Bessborough dr (Leas) MO 2552 — Kathleen stenog h 16 High Park blvd LO 7579 Bartho Geo prod mgr Frlgidalre Products h A 261 Egllnton av e HU 9- 0249 Bartholomew Alan W assmblr Inti Bus Mach h 67 Cedarcrest blvd (E Y) OX 6986 — Albt B bkpr Osier Hammong r 84 Prescott av JU 3347 — Alfreda I stenog Jas M Dunwoody Co r 7 Parkslde dr LO 4717 —Allan J drvr B A Oil res Newmarket — Benj stkpr Candn Fairbanks Morse h 117 Ascot av KE 5828 — Bertha W coll winder Inti Bus Mach r 13 Glasgow av (Scar) — Ernest A real estate 708 Millwood rd (Leas) HU 8-7184 h 188 Airdrie rd (Leas) HU 9-7037 — Ernest A with Tor Hydro h 291 Parkview av (WiUowdale) — Freda I stenog Jas M Dunwoody Co r 7 Parkside dr — Fredk W E rep Annuities Br Dept of Lab h 245 Wright av LO 6472 — Geo J sec-treas Masonic Service Guild of Toronto h 67 Grenview blvd n (Etob) LY 3482 —Greta L Customs Excise h 105, 83 St Clair av w RA 4095 — Hilda Mrs h 84 Prescott av JU 3347 — J I Miss emp Imp Optical — Jean (wid W^ter) h 234 Chambers av (York Twp) LY 9409 ■-John attdt Frank Gabriel h 13 Glasgow av '(Scar) —John Son Ltd Thos Nelson Sons Ltd agts pblshrs 3rd fir, 91-93 Wellington w EM 8- 1796 —Kathleen F r 57 Dentonia Pk av (E Y) GR 2794 — Kurt O rep Sovereign Life Assce h 208, i598A Bathurst (York Twp) RU 1-1422 — Laurence transmitter suprvsr CKEY h 67 Cedarcrest blvd (E Y) — Mabel (wid Chas) h 138 Sutherland dr (Leas) MA 4350 — PhiUip F repairmn Bell Tel r 29 Maybourne av pear) --Rachel (wld Chas) h 20 Curzon HA 6153 —Robt emp Imp Optical r 13 Glasgow av (Scar) — Ruth r 20 Curzon HA 6153 --Wm J sec-treas E C Vance Co Ltd h 57 Dentonia Pk av (E Y) GR 2794 Bartholow Antoni r 198 McCaul Barthorpe Chas G (Barthorpe’s Auto Repair) r 384 Ulster (Etob) —
- 51. Geo H (Barthorpe’s Auto Repair) r 1038 West av (Lakevlew) —Jas foremn Tor Concrete Burial Vault Co h 63 Beechwood av (York Twp) LY 0163 —John H (Barthorpe-s Auto Repair) h 1077 Centre av (Lakeview) Barthorpe’s Auto Repair (Geo, Chas John Barthorpe) 34 Manitoba (Etob) Barthowski Barbara (wid Geo) nurse r 612 Spadina av KI 4381 . Bartle Thos L slsmn Direct Factory Sales h 36 Barclay rd (Nth Y) — Wm acet Ocean Chemicals Ltd h 416 Roxton rd LO 9160 Bartindale B Pearl underwriter Imp Life h 5, 304 Kingsway s (Swan) LY 1392 Bartlrok Ludwig emr O’Keefe’s r 142 Barton av Bartja Mary (wid David) h 14 Virginia av (E Y) OX 8921 Bartkiw David studt r 100 Spadina rd RA 8463 — Peter shpr Crown Tufting Mfg r 58 O’Hara av —Peter studt r 100 Spadina rd RA 8463 Bartkowiak Teodor Ur Shlffer Hllman r 46 Borden RA 6190 — Wladyslaw r 83 MacdoneU av LO 8713 Bartkus Alex emp CNR h 93 Montrose av OL 1650 --Anthony emp King Edward Hotel h 339 Quebec av Alphabetical, White Page 79
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