SlideShare a Scribd company logo
3
Most read
4
Most read
18
Most read
Brain stimulation /
Neurostimulation techniques
Dr. Sujit Kumar Kar
Assistant professor in Psychiatry,
K.G.Medical University, Lucknow
Brain Stimulation
What
How
When
Why
1/7/2018 2
Brief overview of  brain stimulation techniques
Brief overview of  brain stimulation techniques
Novakovic V, Sher L,
Lapidus KA, Mindes J, A
Golier J, Yehuda R. Brain
stimulation in
posttraumatic stress
disorder. Eur J
Psychotraumatol. 2011;2.
Important targets of brain stimulation
1/7/2018 7
Milestones
1785 –
CAMPHOR
INDUCED
SEIZURE (1st
published
report)
1934 – Von
Meduna –
I.M
injection
CAMPHOR
for
induction of
seizure
1938 –
Cerletti &
Bini –
electrical
induction of
seizure
1951 – Use
of Succinyl-
choline
1958 – 1st
controlled
study of
unilateral
ECT
1/7/2018 8
Milestones
1960s- RCTs
comparing
efficacy of
ECT Vs
medication
treatment in
depression
1976-
constant-
current,
brief-pulse
ECT device
1978 – 1st
task force
report for
ECT by APA
1988- RCTs of
ECT Vs Li in
Mania (both
are equally
effective)
1/7/2018 9
ECT, TMS, tDCS, DBS, VNS, MST
What
How
When
Why
1/7/2018 10
Brief overview of  brain stimulation techniques
• Treatment effectiveness of brain
stimulation techniques
Depression – ECT, CES, rTMS, VNS, DBS
OCD – DBS, rTMS
Anxiety - CES
Dystonia, essential tremor– DBS
Epilepsy – DBS, VNS
Parkinson’s disease – DBS
Chronic pain – CES
Insomnia – CES
Schizophrenia : ECT, rTMS, tDCS
Catatonia: ECT
Novakovic V, Sher L, Lapidus KA, Mindes J, A
Golier J, Yehuda R. Brain stimulation in
posttraumatic stress disorder. Eur J
Psychotraumatol. 2011;2.
ECT:
Electroconvulsive
therapy
CES: Cranial
electrotherapy stimul
ation
TMS: Transcranial
magnetic stimulation
MST: Magnetic
seizure therapy
DBS: Deep brain
stimulation
tDCS: Transcranial
Direct
Current Stimulation
VNS: Vagus
nerve stimulation
•Williams NR, Okun MS. Deep
brain stimulation (DBS) at the
interface of neurology and
psychiatry. J Clin Invest. 2013
Nov 1;123(11):4546-56.
Sl.
No.
Brain / Neuro- stimulation
methods
Role in
mood
disorders
Role in
schizophrenia
1 Electroconvulsive therapy
(ECT)
++ ++
2 Trans-cranial electrical
Stimulation
+ +
3 Trans-cranial Direct Current
Stimulation (tDCS) + ?
4 Vagus Nerve Stimulation (VNS) ++ ?
5 Repetitive Trans-cranial
Magnetic Stimulation (rTMS) ++ +
6 Deep Brain Stimulation (DBS) +/- ?
7 Epicranial Stimulation (EpCS) ? ?
8 Magnetic Seizure Therapy
(MTS)
? ?
Sl.
No
.
Brain / Neuro-
stimulation methods
In
epilepsy
In Parkinson’s
disease
1 Electroconvulsive
therapy (ECT)
(+) +/-
2 Trans-cranial electrical
Stimulation
? ?
3 Trans-cranial Direct
Current Stimulation
(tDCS)
? ?
4 Vagus Nerve
Stimulation (VNS)
+ ?
5 Repetitive Trans-
cranial Magnetic
Stimulation (rTMS)
? +/-
6 Deep Brain Stimulation
(DBS)
? ++
Suggested readings
1/7/2018 16
1/7/2018 17
Suggestedreadings
1/7/2018 18
Suggestedreadings
Additional reading
• Kiloh LG, Smith JS, Johnson GF. Electroconvulsive-
therapy. In: Physical treatments in psychiatry.
Melbourne: Blackwell Scientific, 1988: 183-276.
• Scott A I F; The ECT handbook; 2nd edition; 2004; The
Royal College of Psychiatrists 2005
• Sadock, Benjamin J.; Sadock, Virginia A.; Ruiz, Pedro;
Kaplan & Sadock's Comprehensive Textbook of
Psychiatry, 9th Edition; 2009 Lippincott Williams &
Wilkins
• Onion D K; The Little Black Book Of Psychiatry; 3rd
edition;2007
1/7/2018 19
1/7/2018 20

More Related Content

PPTX
Transcranial magnetic stimulation
PPTX
rTMS technique
PPTX
Brain stimulation therapies
PPTX
Intro to Transcranial Direct Curent Stimulation (tDCS)
PPTX
Transcranial Magnetic Stimulation- TMS
PPTX
Moderator roles in a seminar
PPTX
Autism spectrum disorder
PPTX
Neuromodulation in psychiatry.
Transcranial magnetic stimulation
rTMS technique
Brain stimulation therapies
Intro to Transcranial Direct Curent Stimulation (tDCS)
Transcranial Magnetic Stimulation- TMS
Moderator roles in a seminar
Autism spectrum disorder
Neuromodulation in psychiatry.

What's hot (20)

PPTX
PPTX
Brain Stimulation & Neuromodulation September 2016 - BH Summit
PPTX
Endocannabinoids..
PPTX
Deep Brain Stimulation
PPTX
Frontal lobe syndromes
PDF
Transcranial direct current stimulation
PDF
Event Related Potentials
PPT
EEG Maturation - Serial evolution of changes from Birth to Old Age
PPTX
Frontal lobe &psychiatry- ppt
PPTX
Psychosurgery .pptx
PPT
05.31.13 Non-Convulsive Status Epilepticus (NCSE) - Bittel.ppt
PPTX
Sonothrombolysis in acute stroke
PPTX
prefrontal cortex
PPTX
Frontal lobe relation to psychiatry
PPTX
Principles of DBS 31 Jan 2017
PPTX
Anatomy of Frontal lobe
PPTX
Serotonin and its role in psychiatry.pptx
PPTX
Frontal lobe functions and assessmeny 20th july 2013
PPTX
EEG in neurology and psychiatry
PPTX
Frontal lobe and its functions
Brain Stimulation & Neuromodulation September 2016 - BH Summit
Endocannabinoids..
Deep Brain Stimulation
Frontal lobe syndromes
Transcranial direct current stimulation
Event Related Potentials
EEG Maturation - Serial evolution of changes from Birth to Old Age
Frontal lobe &psychiatry- ppt
Psychosurgery .pptx
05.31.13 Non-Convulsive Status Epilepticus (NCSE) - Bittel.ppt
Sonothrombolysis in acute stroke
prefrontal cortex
Frontal lobe relation to psychiatry
Principles of DBS 31 Jan 2017
Anatomy of Frontal lobe
Serotonin and its role in psychiatry.pptx
Frontal lobe functions and assessmeny 20th july 2013
EEG in neurology and psychiatry
Frontal lobe and its functions
Ad

Similar to Brief overview of brain stimulation techniques (20)

PPTX
Non pharmacological Treatments in Psychiatry
PPTX
Neuroprime clinicians
PPT
Magnets - Not Drugs: TMS IMMH San Antonio 2014
PPTX
BRAIN STIMULATION METHODS IN OCD
PDF
The Efficacy of Post Traumatic Stress Disorder Research for Former High Deman...
PDF
Nicotinergic impact on focal and non focal neuroplasticity induced by non-inv...
PDF
ZMPCZM017000.11.03
PDF
ZMPCZM017000.11.03 Carey Experimentation on brain research
PDF
ZMPCZM017000.11.03
PDF
ZMPCZM017000.11.03 Carey Experimentation on brain research
PDF
Beta EEG increased during tDCS
PPTX
Electroconvulsiv Therapy Presentation
PPTX
rev-TBI OXYGENATION, LUND, MANAGEMENT.pptx
PPT
Electro convulsive therapy
PPTX
Role of ECT in psychiatry
PPTX
Electroconvulsive therapy
PPT
Transcranial magnetic stimulation.ppt
PPT
Transcranial magnetic stimulation power point[1].ppt
PPT
Spect in concussion, vertebro basilar insufficiency and other neurological di...
PPTX
Electro convulsive therapy
Non pharmacological Treatments in Psychiatry
Neuroprime clinicians
Magnets - Not Drugs: TMS IMMH San Antonio 2014
BRAIN STIMULATION METHODS IN OCD
The Efficacy of Post Traumatic Stress Disorder Research for Former High Deman...
Nicotinergic impact on focal and non focal neuroplasticity induced by non-inv...
ZMPCZM017000.11.03
ZMPCZM017000.11.03 Carey Experimentation on brain research
ZMPCZM017000.11.03
ZMPCZM017000.11.03 Carey Experimentation on brain research
Beta EEG increased during tDCS
Electroconvulsiv Therapy Presentation
rev-TBI OXYGENATION, LUND, MANAGEMENT.pptx
Electro convulsive therapy
Role of ECT in psychiatry
Electroconvulsive therapy
Transcranial magnetic stimulation.ppt
Transcranial magnetic stimulation power point[1].ppt
Spect in concussion, vertebro basilar insufficiency and other neurological di...
Electro convulsive therapy
Ad

More from Sujit Kumar Kar (20)

PPTX
Organic Psychiatry Delirium and Dementia.pptx
PPTX
Beyond Physical healing - The journey to psychological recovery.pptx
PPTX
SCHIZOPHRENIA: A holistic understanding.pptx
PPTX
Management of anxiety @ Overview of Pharmacotherapy.pptx
PPTX
Addressing culture bound syndromes- need of a culture sensitive approach.pptx
PPTX
Mental Health: What one should know?.pptx
PPTX
Psychopharmacology, ECT & Psychosurgery
PPTX
Qualitative psycho social research
PPTX
Biostatistics ii
PPTX
Mental health issues during global pandemic
PPTX
PPTX
Amisulpride@ use in psychotic illnesses
PPTX
Online psychotherapy
PPTX
Clock face drawing test
PPTX
Identification of psychiatric disorders in primary care settings
PPTX
Schizophrenia
PPTX
Approach to a case of personality disorder
PPTX
Emerging trends in brain stimulation
PPTX
Understanding personality disorders
PPTX
EEG basics for mental health professionals
Organic Psychiatry Delirium and Dementia.pptx
Beyond Physical healing - The journey to psychological recovery.pptx
SCHIZOPHRENIA: A holistic understanding.pptx
Management of anxiety @ Overview of Pharmacotherapy.pptx
Addressing culture bound syndromes- need of a culture sensitive approach.pptx
Mental Health: What one should know?.pptx
Psychopharmacology, ECT & Psychosurgery
Qualitative psycho social research
Biostatistics ii
Mental health issues during global pandemic
Amisulpride@ use in psychotic illnesses
Online psychotherapy
Clock face drawing test
Identification of psychiatric disorders in primary care settings
Schizophrenia
Approach to a case of personality disorder
Emerging trends in brain stimulation
Understanding personality disorders
EEG basics for mental health professionals

Recently uploaded (20)

PPTX
Chapter-1-The-Human-Body-Orientation-Edited-55-slides.pptx
PPTX
surgery guide for USMLE step 2-part 1.pptx
PPTX
antibiotics rational use of antibiotics.pptx
PDF
Therapeutic Potential of Citrus Flavonoids in Metabolic Inflammation and Ins...
PPT
MENTAL HEALTH - NOTES.ppt for nursing students
PPTX
LUNG ABSCESS - respiratory medicine - ppt
PPTX
JUVENILE NASOPHARYNGEAL ANGIOFIBROMA.pptx
PPT
Breast Cancer management for medicsl student.ppt
PPTX
Note on Abortion.pptx for the student note
PPTX
CME 2 Acute Chest Pain preentation for education
PPTX
Transforming Regulatory Affairs with ChatGPT-5.pptx
PPT
genitourinary-cancers_1.ppt Nursing care of clients with GU cancer
PPT
Copy-Histopathology Practical by CMDA ESUTH CHAPTER(0) - Copy.ppt
PPTX
DENTAL CARIES FOR DENTISTRY STUDENT.pptx
PPTX
neonatal infection(7392992y282939y5.pptx
DOC
Adobe Premiere Pro CC Crack With Serial Key Full Free Download 2025
PPTX
Cardiovascular - antihypertensive medical backgrounds
PPT
ASRH Presentation for students and teachers 2770633.ppt
PDF
Copy of OB - Exam #2 Study Guide. pdf
PDF
Oral Aspect of Metabolic Disease_20250717_192438_0000.pdf
Chapter-1-The-Human-Body-Orientation-Edited-55-slides.pptx
surgery guide for USMLE step 2-part 1.pptx
antibiotics rational use of antibiotics.pptx
Therapeutic Potential of Citrus Flavonoids in Metabolic Inflammation and Ins...
MENTAL HEALTH - NOTES.ppt for nursing students
LUNG ABSCESS - respiratory medicine - ppt
JUVENILE NASOPHARYNGEAL ANGIOFIBROMA.pptx
Breast Cancer management for medicsl student.ppt
Note on Abortion.pptx for the student note
CME 2 Acute Chest Pain preentation for education
Transforming Regulatory Affairs with ChatGPT-5.pptx
genitourinary-cancers_1.ppt Nursing care of clients with GU cancer
Copy-Histopathology Practical by CMDA ESUTH CHAPTER(0) - Copy.ppt
DENTAL CARIES FOR DENTISTRY STUDENT.pptx
neonatal infection(7392992y282939y5.pptx
Adobe Premiere Pro CC Crack With Serial Key Full Free Download 2025
Cardiovascular - antihypertensive medical backgrounds
ASRH Presentation for students and teachers 2770633.ppt
Copy of OB - Exam #2 Study Guide. pdf
Oral Aspect of Metabolic Disease_20250717_192438_0000.pdf

Brief overview of brain stimulation techniques

  • 1. Brain stimulation / Neurostimulation techniques Dr. Sujit Kumar Kar Assistant professor in Psychiatry, K.G.Medical University, Lucknow
  • 5. Novakovic V, Sher L, Lapidus KA, Mindes J, A Golier J, Yehuda R. Brain stimulation in posttraumatic stress disorder. Eur J Psychotraumatol. 2011;2.
  • 6. Important targets of brain stimulation
  • 8. Milestones 1785 – CAMPHOR INDUCED SEIZURE (1st published report) 1934 – Von Meduna – I.M injection CAMPHOR for induction of seizure 1938 – Cerletti & Bini – electrical induction of seizure 1951 – Use of Succinyl- choline 1958 – 1st controlled study of unilateral ECT 1/7/2018 8
  • 9. Milestones 1960s- RCTs comparing efficacy of ECT Vs medication treatment in depression 1976- constant- current, brief-pulse ECT device 1978 – 1st task force report for ECT by APA 1988- RCTs of ECT Vs Li in Mania (both are equally effective) 1/7/2018 9
  • 10. ECT, TMS, tDCS, DBS, VNS, MST What How When Why 1/7/2018 10
  • 12. • Treatment effectiveness of brain stimulation techniques Depression – ECT, CES, rTMS, VNS, DBS OCD – DBS, rTMS Anxiety - CES Dystonia, essential tremor– DBS Epilepsy – DBS, VNS Parkinson’s disease – DBS Chronic pain – CES Insomnia – CES Schizophrenia : ECT, rTMS, tDCS Catatonia: ECT Novakovic V, Sher L, Lapidus KA, Mindes J, A Golier J, Yehuda R. Brain stimulation in posttraumatic stress disorder. Eur J Psychotraumatol. 2011;2. ECT: Electroconvulsive therapy CES: Cranial electrotherapy stimul ation TMS: Transcranial magnetic stimulation MST: Magnetic seizure therapy DBS: Deep brain stimulation tDCS: Transcranial Direct Current Stimulation VNS: Vagus nerve stimulation
  • 13. •Williams NR, Okun MS. Deep brain stimulation (DBS) at the interface of neurology and psychiatry. J Clin Invest. 2013 Nov 1;123(11):4546-56.
  • 14. Sl. No. Brain / Neuro- stimulation methods Role in mood disorders Role in schizophrenia 1 Electroconvulsive therapy (ECT) ++ ++ 2 Trans-cranial electrical Stimulation + + 3 Trans-cranial Direct Current Stimulation (tDCS) + ? 4 Vagus Nerve Stimulation (VNS) ++ ? 5 Repetitive Trans-cranial Magnetic Stimulation (rTMS) ++ + 6 Deep Brain Stimulation (DBS) +/- ? 7 Epicranial Stimulation (EpCS) ? ? 8 Magnetic Seizure Therapy (MTS) ? ?
  • 15. Sl. No . Brain / Neuro- stimulation methods In epilepsy In Parkinson’s disease 1 Electroconvulsive therapy (ECT) (+) +/- 2 Trans-cranial electrical Stimulation ? ? 3 Trans-cranial Direct Current Stimulation (tDCS) ? ? 4 Vagus Nerve Stimulation (VNS) + ? 5 Repetitive Trans- cranial Magnetic Stimulation (rTMS) ? +/- 6 Deep Brain Stimulation (DBS) ? ++
  • 19. Additional reading • Kiloh LG, Smith JS, Johnson GF. Electroconvulsive- therapy. In: Physical treatments in psychiatry. Melbourne: Blackwell Scientific, 1988: 183-276. • Scott A I F; The ECT handbook; 2nd edition; 2004; The Royal College of Psychiatrists 2005 • Sadock, Benjamin J.; Sadock, Virginia A.; Ruiz, Pedro; Kaplan & Sadock's Comprehensive Textbook of Psychiatry, 9th Edition; 2009 Lippincott Williams & Wilkins • Onion D K; The Little Black Book Of Psychiatry; 3rd edition;2007 1/7/2018 19