The 10th International Conference on Parallel, Distributed Computing and Applications (IPDCA 2021) will take place on April 24-25, 2021, in Copenhagen, Denmark, focusing on advancements in parallel and distributed computing. Original papers on various topics, including algorithms, bioinformatics, computer networks, and cyber security are invited, with submissions due by April 3, 2021. Selected papers will be published in various indexed journals after further revisions.