This document compares the AERMOD and CALPUFF air dispersion models for regulatory modelling in the Alberta oil sands region. The study found that concentrations can vary considerably between the two models depending on model inputs and settings. CALPUFF predictions were higher closer to sources while AERMOD distributed pollution farther. Both models were sensitive to meteorological data and parameters. For large-scale regional modelling of multiple oil sands sources, CALPUFF is more appropriate, while AERMOD could be used for individual sources.