Can Peng Chapter 7 Presentation final draft
- 1. Three commonly used classes of drugs for the respiratory system conditions Antibiotic kills bacteria. Antihistamine blocks allergy attack. Corticosteroid reduces inflammation and swelling. 1
- 2. The PDR contains information on all the drugs licensed by the U.S. Food and Drug Administration (FDA). • Classes • Boxed Warning • DEA class (prescription or OTC) • Description • Common brand names • How supplied • Dosage and indications • Maximum dosage • Dosing considerations • Administration • Storage • Contraindications/precautions • Adverse reactions • Drug interactions • Pregnancy and lactation • Mechanism of action • Pharmokinetics Physicians' Desk Reference (PDR) 2 Web photo retrieved from https://groups.diigo.com/group/berfdilycoc30/content/physicians-desk-reference-pictures-6970757
- 3. 3 Antibiotic • A type of antimicrobial drug which treats and prevents bacterial infections • May either kill or inhibit the growth of bacteria • May also possess antiprotozoal activity • Not effective against viruses such as the common cold or influenza Web photo retrieved from https://haywardmemorialhospital.com/about-us/antibiotic-awareness/
- 4. 4 Antibiotic Ciprofloxacin hydrochloride (Cipro) • Classes: Fluoroquinolone antibiotic Ophthalmological anti-infective Auricular (Otic) anti-infective • DEA Class: A medical prescription (Rx) • Common brand names: Cetraxal, Ciloxan, Cipro, Cipro XR, OTIPRIO, Proquin XR Web photo retrieved from https:// www.epainassist.com/opioid-treatment/medications/how-effective-is-cipro-and-what-are-its-side-effects
- 5. 5 Antibiotic Ciprofloxacin hydrochloride (Cipro) • Description: Oral, intravenous (IV), ophthalmic, otic broad- spectrum fluoroquinolone anti-infective Used for urinary tract infections, respiratory tract infections, skin and skin structure infections, infectious diarrhea, anthrax, plague, corneal ulcers, bacterial conjunctivitis, acute otitis externa, and bilateral otitis media with effusion in patients undergoing tympanostomy tube placement • Adverse reactions: Associated with disabling and potentially irreversible adverse events, including tendonitis, tendon rupture, and peripheral neuropathy Web photo retrieved from https:// www.epainassist.com/opioid-treatment/medications/how-effective-is-cipro-and-what-are-its-side-effects
- 6. 6 Web photo retrieved from https:// www.epainassist.com/opioid-treatment/medications/how-effective-is-cipro-and-what-are-its-side-effects Antibiotic Ciprofloxacin hydrochloride (Cipro) • How supplied: Cetraxal/Ciprofloxacin/Ciprofloxacin Hydrochloride Otic Solution: 0.2% Ciloxan Ophthalmic Ointment: 0.3% Ciloxan/Ciprofloxacin/Ciprofloxacin Hydrochloride Ophthalmic Solution: 0.3% Cipro XR/Ciprofloxacin/Ciprofloxacin Hydrochloride/Proquin XR Oral Tablet ER: 500 mg, 1000 mg Cipro/Ciprofloxacin Oral Pwd F/Recon: 5 mL, 250 mg, 500 mg Cipro/Ciprofloxacin/Ciprofloxacin Hydrochloride Oral Tablet: 100 mg, 250 mg, 500 mg, 750 mg Cipro/Ciprofloxacin/Ciprofloxacin, Dextrose Intravenous Injection Solution: 1 mL, 10 mg, 2- 5% OTIPRIO Intratympanic Suspension: 6%
- 7. 7 Antihistamine Histamine Structure • An inexpensive, generic drug which treats allergic rhinitis and other allergies, with few side effects • Can give relief when a person has nasal congestion, sneezing, or hives because of pollen, dust mites, or animal allergy • Usually for short-term treatment • Might not treat health problems caused by chronic allergies, including asthma, sinusitis, and lower respiratory tract infection • Need doctors’ guidance for any long-term use Web photo retrieved from https://en.wikipedia.org/wiki/Antihistamine#cite_note-Consumer_Reports_2013-1
- 8. 8 Antihistamine Web photo retrieved from https://www.pharmcom.com/allergy-cough-cold/101-allegra-telfast-180mg-30-tablets.html Fexofenadine hydrochloride (Allegra) • Classes: Second generation (non-sedating) antihistamine • DEA Class: Rx, OTC • Common brand names: Allegra, Allegra Allergy 12 Hour, Allegra Allergy 24 Hour, Allegra Children's Allergy, Allegra Children's Allergy ODT, Allegra ODT, Children's Allergy Fexofenadine
- 9. 9 Antihistamine Web photo retrieved from https://www.pharmcom.com/allergy-cough-cold/101-allegra-telfast-180mg-30-tablets.html Fexofenadine hydrochloride (Allegra) • Description: Non-sedating antihistamine (H1-receptor antagonist) Used for seasonal allergic rhinitis and chronic idiopathic urticaria Active metabolite of terfenadine • Adverse reactions: Severe Anaphylactoid reactions / Rapid Angioedema / Rapid Moderate Unspecified chest pain / Early Dyspnea / Early
- 10. 10 Antihistamine Web photo retrieved from https://www.pharmcom.com/allergy-cough-cold/101-allegra-telfast-180mg-30-tablets.html Fexofenadine hydrochloride (Allegra) • How supplied: Allegra Children's Allergy ODT/Allegra ODT Oral Tab Orally Dis: 30 mg Allegra/Allegra Allergy 12 Hour/Allegra Allergy 24 Hour/Allegra Children's Allergy/Fexofenadine/Fexofenadine Hydrochloride Oral Tablet: 30 mg, 60 mg, 180 mg Allegra/Allegra Children's Allergy/Children's Allergy Fexofenadine/Fexofenadine/Fexofenadine Hydrochloride Oral Suspension: 5 mL, 30 mg
- 11. 11 Corticosteroid Cortisol (hydrocortisone), is a corticosteroid with both glucocorticoid and mineralocorticoid activity and effects • A class of steroid hormones that are produced in the adrenal cortex (cortisol and aldosterone), as well as the synthetic analogues of these hormones. • Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. • Some common naturally occurring steroid hormones are cortisol, corticosterone, cortisone and aldosterone. Web photo retrieved from https://en.wikipedia.org/wiki/Corticosteroid
- 12. 12 Corticosteroid Web photo retrieved from https://www.epainassist.com/opioid-treatment/medications/how-effective-is-flonase Fluticasone propionate (Flonase) • Classes: Corticosteroids, Inhalant Plain Topical Corticosteroids Topical Nasal Corticosteroids • DEA Class: Rx, OTC • Common brand names: ARMONAIR RESPICLICK, ARNUITY ELLIPTA, Cutivate, Flonase, Flonase Allergy Relief, Flonase Sensimist, Flovent Diskus, Flovent HFA, Veramyst, XHANCE
- 13. 13 Corticosteroid Web photo retrieved from https://www.epainassist.com/opioid-treatment/medications/how-effective-is-flonase Fluticasone propionate (Flonase) • Description: Synthetic corticosteroid; used topically, intranasally, and by oral inhalation Medium-potency topical products are used for corticosteroid-responsive dermatoses, including atopic dermatitis, in adults and pediatric patients 3 months and older. Used via oral inhalation for maintenance treatment of asthma or chronic obstructive pulmonary disease (COPD); used intranasally for allergic / non-allergic rhinitis and for nasal polyps
- 14. 14 Corticosteroid Web photo retrieved from https://www.epainassist.com/opioid-treatment/medications/how-effective-is-flonase Fluticasone propionate (Flonase) • How supplied: ARMONAIR RESPICLICK/ARNUITY ELLIPTA Respiratory (Inhalation) Inhalant: 1 actuation, 50 mcg, 55 mcg, 100 mcg, 113 mcg, 200 mcg, 232 mcg Cutivate/Fluticasone Propionate Topical Cream: 0.05% Cutivate/Fluticasone Propionate Topical Lotion: 0.05% Cutivate/Fluticasone Propionate Topical Ointment: 0.005% Flonase/Flonase Allergy Relief/Flonase Sensimist/Fluticasone Propionate Nasal Spray Met: 1 actuation, 27.5 mcg, 50 mcg Flovent Diskus Respiratory (Inhalation) Pwd: 1 actuation, 50 mcg, 100 mcg, 250 mcg Flovent HFA Respiratory (Inhalation) Aer Met: 1 actuation, 44 mcg, 110 mcg, 220 mcg XHANCE Intrasinal Spray Met: 1 actuation, 93 mcg
- 15. 15 References 1. Prescribers’ Digital Reference, http://www.pdr.net/. 2. Antibiotic, Wikipedia, https://en.wikipedia.org/wiki/Antibiotic. 3. “Utilizing antibiotics agents effectively will preserve present day medication”. News Ghana. 21 November 2015. Retrieved 21 November 2015. 4. “Antibiotics”. NHS. 5 June 2014. Retrieved 17 January 2015. 5. “Factsheet for experts”. European Centre for Disease Prevention and Control. Retrieved 21 December 2014. 6. Chemical Analysis of Antibiotic Residues in Food (PDF). John Wiley & Sons, Inc. 2012. pp. 1–60. ISBN 9781449614591. 7. Antihistamine, Wikipedia, https://en.wikipedia.org/wiki/Antihistamine. 8. Consumer Reports (2013), Using Antihistamines to Treat Allergies, Hay Fever, & Hives - Comparing Effectiveness, Safety, and Price (PDF), Yonkers, New York: Consumer Reports. 9. Corticosteroid, Wikipedia, https://en.wikipedia.org/wiki/Corticosteroid. 10. Nussey, S.; Whitehead, S. (2001). Endocrinology: An Integrated Approach. Oxford: BIOS Scientific Publishers. 11. Nussey, Stephen; Whitehead, Saffron (2001-01-01). The adrenal gland. BIOS Scientific Publishers.
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