THE CARDIAC CYCLE   Lecture 3
Cardiac cycle Describing the sequence of events in one heart beat
Cardiac cycle  Contraction of the myocardium generates pressure changes which result in the orderly movement of blood.  Blood flows from an area of  high pressure  to an area of  low pressure , unless flow is blocked by a valve.  Events on the right and left sides of the heart are the same, but pressures are lower on the right.
 
 
ATRIAL SYSTOLE   The end of diastole
ATRIAL SYSTOLE - Heart Prior to atrial systole, blood has been flowing passively from the atrium into the ventricle through the open AV valve.  Contraction of atria propels some additional blood into the ventricles. Atrial contraction is complete before the ventricle begins to contract.
ATRIAL SYSTOLE Pressures & Volumes The "a" wave occurs when the atrium contracts, increasing atrial pressure (yellow).  Blood arriving at the heart cannot enter the atrium so it flows back up the jugular vein, causing the first discernible wave in the jugular venous pulse.  Atrial pressure drops when the atria stop contracting.
ATRIAL SYSTOLE ECG An impulse arising from the SA node results in depolarization and contraction of the atria (the right atrium contracts slightly before the left atrium).  The P wave is due to this atrial depolarization. The PR segment is electrically quiet as the depolarization proceeds to the AV node.  This brief pause before contraction allows the ventricles to fill completely with blood.
ATRIAL SYSTOLE Heart Sounds A fourth heart sound (S4) is abnormal and is associated with the end of atrial emptying after atrial contraction.  It occurs with hypertrophic congestive heart failure, massive pulmonary embolism, or tricuspid incompetence.
ISOVOLUMETRIC CONTRACTION The Beginning of systole
ISOVOLUMETRIC CONTRACTION Heart The atrioventricular (AV) valves close at the beginning of this phase. Electrically, ventricular systole is defined as the interval between the QRS complex and the end of the T wave (the Q-T interval). Mechanically, ventricular systole is defined as the interval between the closing of the AV valves and the opening of the semilunar valves (aortic and pulmonary valves).
ISOVOLUMETRIC CONTRACTION Pressures & Volumes The AV valves close when the pressure in the ventricles (red) exceeds the pressure in the atria (yellow).  As the ventricles contract isovolumetrically -- their volume does not change (white) -- the pressure inside increases, approaching the pressure in the aorta and pulmonary arteries (green).
ISOVOLUMETRIC CONTRACTION ECG The electrical impulse propagates from the AV node through the His bundle and Purkinje system to allow the ventricles to contract from the apex of the heart towards the base. The QRS complex is due to ventricular depolarization, and it marks the beginning of ventricular systole. It is so large that it masks the underlying atrial repolarization signal. the ventricles to fill completely with blood.
ISOVOLUMETRIC CONTRACTION Heart Sounds The first heart sound (S1, "lub") is due to the closing AV valves .
RAPID EJECTION
RAPID EJECTION Heart The semilunar (aortic and pulmonary) valves open at the beginning of this phase.
RAPID EJECTION Pressures & Volumes While the ventricles continue contracting, the pressure in the ventricles (red) exceeds the pressure in the aorta and pulmonary arteries (green); the semilunar valves open, blood exits the ventricles, and the volume in the ventricles decreases rapidly (white). As more blood enters the arteries, pressure there builds until the flow of blood reaches a peak. The "c" wave of atrial pressure is not normally visible in the jugular venous pulse. Right ventricular contraction pushes the tricuspid valve into the atrium and increases atrial pressure, creating a small wave into the jugular vein. It is normally simultaneous with the carotid pulse.
RAPID EJECTION ECG and Heart sounds ECG- No Deflections Heart Sounds- None
REDUCED EJECTION   The end of systole
REDUCED EJECTION Heart At the end of this phase the semilunar (aortic and pulmonary) valves close.
REDUCED EJECTION Pressures & Volumes After the peak in ventricular and arterial pressures (red and green), blood flow out of the ventricles decreases and ventricular volume decreases more slowly (white). When the pressure in the ventricles falls below the pressure in the arteries, blood in the arteries begins to flow back toward the ventricles and causes the semilunar valves to close. This marks the end of ventricular systole mechanically.
REDUCED EJECTION ECG and Heart Sounds The T wave is due to ventricular repolarization. The end of the T wave marks the end of ventricular systole electrically.  Heart Sounds- None
ISOVOLUMETRIC RELAXATION   The beginning of Diastole
ISOVOLUMETRIC RELAXATION Heart At the beginning of this phase the AV valves are closed.
ISOVOLUMETRIC RELAXATION Pressures & Volumes Throughout this and the previous two phases, the atrium in diastole has been filling with blood on top of the closed AV valve, causing atrial pressure to rise gradually (yellow). The "v" wave is due to the back flow of blood after it hits the closed AV valve. It is the second discernible wave of the jugular venous pulse. The pressure in the ventricles (red) continues to drop.  Ventricular volume (white) is at a minimum and is ready to be filled again with blood.
ISOVOLUMETRIC RELAXATION ECG ECG- No Deflections  Heart sounds-  The second heart sound (S2, "dup") occurs when the semilunar (aortic and pulmonary) valves close. S2 is normally split because the aortic valve closes slightly earlier than the pulmonary valve.
RAPID VENTRICULAR FILLING
RAPID VENTRICULAR FILLING Heart Once the AV valves open, blood that has accumulated in the atria flows rapidly into the ventricles.
RAPID VENTRICULAR FILLING Pressures & Volumes Ventricular volume (white) increases rapidly as blood flows from the atria into the ventricles.
RAPID VENTRICULAR FILLING ECG No Deflections  Heart sounds- A third heart sound (S3) is usually abnormal and is due to rapid passive ventricular filling. It occurs in dilated congestive heart failure, severe hypertension, myocardial infarction, or mitral incompetence.
REDUCED VENTRICULAR FILLING   (Diastasis)
REDUCED VENTRICULAR FILLING Heart Rest of blood that has accumulated in the atria flows slowly into the ventricles.
REDUCED VENTRICULAR FILLING Pressures & Volumes Ventricular volume (white) increases more slowly now. The ventricles continue to fill with blood until they are nearly full.
REDUCED VENTRICULAR FILLING  ECG ECG- No Deflections  Heart Sounds- None

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Cardiovascular System3

  • 1. THE CARDIAC CYCLE Lecture 3
  • 2. Cardiac cycle Describing the sequence of events in one heart beat
  • 3. Cardiac cycle Contraction of the myocardium generates pressure changes which result in the orderly movement of blood. Blood flows from an area of high pressure to an area of low pressure , unless flow is blocked by a valve. Events on the right and left sides of the heart are the same, but pressures are lower on the right.
  • 4.  
  • 5.  
  • 6. ATRIAL SYSTOLE The end of diastole
  • 7. ATRIAL SYSTOLE - Heart Prior to atrial systole, blood has been flowing passively from the atrium into the ventricle through the open AV valve. Contraction of atria propels some additional blood into the ventricles. Atrial contraction is complete before the ventricle begins to contract.
  • 8. ATRIAL SYSTOLE Pressures & Volumes The "a" wave occurs when the atrium contracts, increasing atrial pressure (yellow). Blood arriving at the heart cannot enter the atrium so it flows back up the jugular vein, causing the first discernible wave in the jugular venous pulse. Atrial pressure drops when the atria stop contracting.
  • 9. ATRIAL SYSTOLE ECG An impulse arising from the SA node results in depolarization and contraction of the atria (the right atrium contracts slightly before the left atrium). The P wave is due to this atrial depolarization. The PR segment is electrically quiet as the depolarization proceeds to the AV node. This brief pause before contraction allows the ventricles to fill completely with blood.
  • 10. ATRIAL SYSTOLE Heart Sounds A fourth heart sound (S4) is abnormal and is associated with the end of atrial emptying after atrial contraction. It occurs with hypertrophic congestive heart failure, massive pulmonary embolism, or tricuspid incompetence.
  • 11. ISOVOLUMETRIC CONTRACTION The Beginning of systole
  • 12. ISOVOLUMETRIC CONTRACTION Heart The atrioventricular (AV) valves close at the beginning of this phase. Electrically, ventricular systole is defined as the interval between the QRS complex and the end of the T wave (the Q-T interval). Mechanically, ventricular systole is defined as the interval between the closing of the AV valves and the opening of the semilunar valves (aortic and pulmonary valves).
  • 13. ISOVOLUMETRIC CONTRACTION Pressures & Volumes The AV valves close when the pressure in the ventricles (red) exceeds the pressure in the atria (yellow). As the ventricles contract isovolumetrically -- their volume does not change (white) -- the pressure inside increases, approaching the pressure in the aorta and pulmonary arteries (green).
  • 14. ISOVOLUMETRIC CONTRACTION ECG The electrical impulse propagates from the AV node through the His bundle and Purkinje system to allow the ventricles to contract from the apex of the heart towards the base. The QRS complex is due to ventricular depolarization, and it marks the beginning of ventricular systole. It is so large that it masks the underlying atrial repolarization signal. the ventricles to fill completely with blood.
  • 15. ISOVOLUMETRIC CONTRACTION Heart Sounds The first heart sound (S1, "lub") is due to the closing AV valves .
  • 17. RAPID EJECTION Heart The semilunar (aortic and pulmonary) valves open at the beginning of this phase.
  • 18. RAPID EJECTION Pressures & Volumes While the ventricles continue contracting, the pressure in the ventricles (red) exceeds the pressure in the aorta and pulmonary arteries (green); the semilunar valves open, blood exits the ventricles, and the volume in the ventricles decreases rapidly (white). As more blood enters the arteries, pressure there builds until the flow of blood reaches a peak. The "c" wave of atrial pressure is not normally visible in the jugular venous pulse. Right ventricular contraction pushes the tricuspid valve into the atrium and increases atrial pressure, creating a small wave into the jugular vein. It is normally simultaneous with the carotid pulse.
  • 19. RAPID EJECTION ECG and Heart sounds ECG- No Deflections Heart Sounds- None
  • 20. REDUCED EJECTION The end of systole
  • 21. REDUCED EJECTION Heart At the end of this phase the semilunar (aortic and pulmonary) valves close.
  • 22. REDUCED EJECTION Pressures & Volumes After the peak in ventricular and arterial pressures (red and green), blood flow out of the ventricles decreases and ventricular volume decreases more slowly (white). When the pressure in the ventricles falls below the pressure in the arteries, blood in the arteries begins to flow back toward the ventricles and causes the semilunar valves to close. This marks the end of ventricular systole mechanically.
  • 23. REDUCED EJECTION ECG and Heart Sounds The T wave is due to ventricular repolarization. The end of the T wave marks the end of ventricular systole electrically. Heart Sounds- None
  • 24. ISOVOLUMETRIC RELAXATION The beginning of Diastole
  • 25. ISOVOLUMETRIC RELAXATION Heart At the beginning of this phase the AV valves are closed.
  • 26. ISOVOLUMETRIC RELAXATION Pressures & Volumes Throughout this and the previous two phases, the atrium in diastole has been filling with blood on top of the closed AV valve, causing atrial pressure to rise gradually (yellow). The "v" wave is due to the back flow of blood after it hits the closed AV valve. It is the second discernible wave of the jugular venous pulse. The pressure in the ventricles (red) continues to drop. Ventricular volume (white) is at a minimum and is ready to be filled again with blood.
  • 27. ISOVOLUMETRIC RELAXATION ECG ECG- No Deflections Heart sounds- The second heart sound (S2, "dup") occurs when the semilunar (aortic and pulmonary) valves close. S2 is normally split because the aortic valve closes slightly earlier than the pulmonary valve.
  • 29. RAPID VENTRICULAR FILLING Heart Once the AV valves open, blood that has accumulated in the atria flows rapidly into the ventricles.
  • 30. RAPID VENTRICULAR FILLING Pressures & Volumes Ventricular volume (white) increases rapidly as blood flows from the atria into the ventricles.
  • 31. RAPID VENTRICULAR FILLING ECG No Deflections Heart sounds- A third heart sound (S3) is usually abnormal and is due to rapid passive ventricular filling. It occurs in dilated congestive heart failure, severe hypertension, myocardial infarction, or mitral incompetence.
  • 33. REDUCED VENTRICULAR FILLING Heart Rest of blood that has accumulated in the atria flows slowly into the ventricles.
  • 34. REDUCED VENTRICULAR FILLING Pressures & Volumes Ventricular volume (white) increases more slowly now. The ventricles continue to fill with blood until they are nearly full.
  • 35. REDUCED VENTRICULAR FILLING ECG ECG- No Deflections Heart Sounds- None