This document contains information about genetics and mutations, as well as discussion topics related to the novel "My Sister's Keeper" and the concept of designer babies. It includes questions about DNA replication and how mutations occur, the difference between spontaneous and induced mutations, and what mutagens are. It provides a summary of the plot of "My Sister's Keeper" about a girl designed to be a genetic match for her sister with leukemia. It includes links to additional background information on the science and ethics of the novel, as well as discussion questions about designer babies, organ donation, and the movie "Gattaca".