The document discusses the history and effects of alcohol use. It describes how the temperance movement sought to curb alcohol abuse in the early 1800s. The 18th amendment established prohibition in 1920 but was later repealed due to problems with illegal alcohol trade. Moderate drinking is generally safe but binge and heavy drinking can negatively impact the brain, liver, heart and increase cancer risk. The highest rates of alcohol consumption and binge drinking are seen in college students and young adults.