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@ IJTSRD | Available Online @ www.ijtsrd.com
ISSN No: 2456
International
Research
Chronological Development
Dr. Gajendra Kumar Sahu
1,2
MD Scholar
PG Department of Rasshastra and Bhaishajyakalpana
ABSTRACT
Rasa shastra is a most important and popular branch
of Ayurveda It deals with the knowledge related to
alchemy( Lohavedh) and Ayurvedic Pharmaceutics
specially connected to the drugs of mineral
with a view to remove poverty from the world and to
strengthen the body and also to prevent their ageing
process. History of Rasa Shastra can be traced in pre
vedic period where metals are successfully employed
in treatment of various diseases. Its development was
rapid after Lord Buddha and the influence of the
philosophy of Ahimsa. This was the era when Rasa
Shastra flourished tremendously. It was recognized as
a medical science with an independent philosophical
background in 14th century, by Madhavacharya in his
book Sarva Darsana Samgraha. Considering the
importance of this discipline in Ayurvedic
therapeutics and the fact that there is dearth of
comprehensive review on the subject an attempt has
been made in this review to provide a brief but all
encompassing coverage of different aspects related to
it.
Keywords: Alchemy, Ahimsa, Lohavedh
INTRODUCTION
Etymologically the word “Rasa” is use
the metal Mercury, also known as quicksilver. The
word “Shastra” means knowledge or sacred
The term Rasa shastra, therefore could be translated
as the ‘science of mercury’. Rasshastra or the
Ayurvedic alchemy is an important branch of
Ayurvedic pharmacology which deals with the metals,
minerals the gemstones, animal products and herb
ingredients, highly medicinal co mounds were
formulated for rejuvenation, the cure for chronic
@ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 5 | Jul-Aug
ISSN No: 2456 - 6470 | www.ijtsrd.com | Volume
International Journal of Trend in Scientific
Research and Development (IJTSRD)
International Open Access Journal
Chronological Development of Rasa Shastra
Dr. Gajendra Kumar Sahu1
, Dr. Kavita2
, Dr. S. M. Parhate3
, K. S
MD Scholar, 3
Professor and HOD, 4
Reader
of Rasshastra and Bhaishajyakalpana Govt. Ayurvedic C
Raipur, Chhattisgarh, India
Rasa shastra is a most important and popular branch
of Ayurveda It deals with the knowledge related to
alchemy( Lohavedh) and Ayurvedic Pharmaceutics
specially connected to the drugs of mineral origin
with a view to remove poverty from the world and to
strengthen the body and also to prevent their ageing
process. History of Rasa Shastra can be traced in pre
vedic period where metals are successfully employed
development was
rapid after Lord Buddha and the influence of the
This was the era when Rasa
Shastra flourished tremendously. It was recognized as
a medical science with an independent philosophical
vacharya in his
Considering the
importance of this discipline in Ayurvedic
therapeutics and the fact that there is dearth of
comprehensive review on the subject an attempt has
been made in this review to provide a brief but all
encompassing coverage of different aspects related to
Etymologically the word “Rasa” is used to describe
, also known as quicksilver. The
s knowledge or sacred scripture.
therefore could be translated
as the ‘science of mercury’. Rasshastra or the
Ayurvedic alchemy is an important branch of
Ayurvedic pharmacology which deals with the metals,
animal products and herbal
mounds were
formulated for rejuvenation, the cure for chronic
disease and ultimately life extension.
dravya have the following three characteristic
attributes: instant effectiveness, requirement of very
small doses and extensive therapeutic utility
irrespective of constitutional variation. The origin of
Rasa sastra has its roots in the Indian alchemy
Alchemy was a form of chemistry studied in the
medieval period, in which people tried to discover
different ways to change ordinary metals into gold.
This practice went on for centuries, yielding some of
the significant findings in the field of alchemy.
Vedic Kala
 Rigveda reveals that copper, gold, Iron and some
other metals and minerals have been used in that
period.2
 Rigveda refers to Asvins substituting the lost leg
of Vishala by a thigh made of iron.
 Yajurveda enumerated a list of metals &minerls
Ayas, Hiranya, Syam (copper),
Trapu (Tin).
 According to a quotation in Yajurveda Swarna is
useful in improving longevity, lusture, Strength.
 In Atharvveda Hiranyadarshanphala and its
internal use are mentioned
 Chandogya Upanishad –
medicine.
 Transmutation of lower metals into gold has been
described in Taittariyabramhana.
 As per Manusmriti During the birth ritual of a
baby Swarnaprasana is indicated.
 The description of metals like Swarna, Rajat etc.
and precious stones like Manikya, etc. is available
in Garuda Purana, Agni Purana, and Devi bhagvat.
2018 Page: 47
6470 | www.ijtsrd.com | Volume - 2 | Issue – 5
Scientific
(IJTSRD)
International Open Access Journal
f Rasa Shastra
S Karbhal4
College,
disease and ultimately life extension.1
The Rasa
dravya have the following three characteristic
attributes: instant effectiveness, requirement of very
ll doses and extensive therapeutic utility
irrespective of constitutional variation. The origin of
its roots in the Indian alchemy.
Alchemy was a form of chemistry studied in the
medieval period, in which people tried to discover
ways to change ordinary metals into gold.
This practice went on for centuries, yielding some of
the significant findings in the field of alchemy.
Rigveda reveals that copper, gold, Iron and some
other metals and minerals have been used in that
Rigveda refers to Asvins substituting the lost leg
of Vishala by a thigh made of iron.
Yajurveda enumerated a list of metals &minerls –
Ayas, Hiranya, Syam (copper), Loha, Sisa (Lead),
According to a quotation in Yajurveda Swarna is
seful in improving longevity, lusture, Strength.3
Hiranyadarshanphala and its
internal use are mentioned
– Tikshnaloha used as
Transmutation of lower metals into gold has been
described in Taittariyabramhana.
per Manusmriti During the birth ritual of a
baby Swarnaprasana is indicated.
The description of metals like Swarna, Rajat etc.
and precious stones like Manikya, etc. is available
in Garuda Purana, Agni Purana, and Devi bhagvat.
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
@ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 5 | Jul-Aug 2018 Page: 48
CharakaSamhita
Caraka has classified drugs into three categories –
1. Sthavar
2. Jangam
3. Bhaum
The third category includes gold, iron, copper, tin
etc.4
 Manhshila, Haratala, Kasis, are used for external
application for purpose of external application.
 Shodhana of Parthivdravya are mentioned in
charakasamhita.5
 Suvarna and Rouya are used for purose of
PunsavanSamsakara.6
 Lohadi Rasayana is indicated for Rasayana
Karma7
 Vaidurya, Mukta, Manibhasma, Gairika, Shankha,
Suvarnabhasma has used in udakakalpana for
Raktaittachikitsa.8
 There is no direct reference of Parad is mentioned
in Charak Samhita. But in charakakushtha-chikitsa
adhyay the word “Ras” is used.
 Different types of Loha, Tapya, Adrija, Rouya,
Makskika etc. has used in variety of yogas for
Panduchikitsa.
 Mukta, Praval, Vaidurya , Shankh, Shatika,
Anjana, Gandhaka has used in Shwasvyadhi as
Muktadyachurna with Madhu and Sarpi.
 Tamra used in garavisha for vamana and suvarna
with Madhuasvishagna yoga.9
 Vajra, Markata, Vishamushika, vaidurya are used
for sarpadanshanivaran.
 Manahashila used as pradhamannasyain
kaphajpratishyay.
 Pitakchurna (Manhshila, Hartala, Yavakshara,
Saindhav has used in Pitakchurna to treat
mukharoga.
 We see that Dhatus were administered in the form
of powder (Raja) only and the concept of bhasmas
was not developed during the classical age.
Sushruta Samhita
In this Samhita also references of Theraeutic
applications of mineral and metallic substances are
found abundantly.
 Trapvadigana and usakadigana are described,
various dhatus are mentioned in these gana.
 Several Yantra and Shastra used in surgical
process are made of different kinds of metals or
alloys.
 Ayaskriti is the specific contribution of
Sushrutasamhita.11
 Surprisingly external application of mercury is
also evident in Sushruta Samhita.
 Acharya Sushruta mention of pakas namely
Sthalipaka. etc.
 Dhatuvish – Phenashma and Hartala were first
time introduced in Sushruta Samhita.
 Internal administration of Anjana is first time
indicated in Sushruta Samhita.
 Various Dhatus are mentioned for internal
administration in Dravya Sangrahniya adhyay.
 Two bhedas of lauha is described in
SushrutaSamhita. Tikshnalauhaand kala lauha.
 Vibhitakkashtha is used for burning of Mandur.12
 Gandhaka is used in Mahavajrataila for
kushthachikitsa.
 SwarnaPrashan is indicated in new born child.13
 The word bhasma mentioned in Sushrutasamhita
(Sutra 2 & Kalpa 6) only the ash of vegetable
drugs.
 The concept of Puta appears to be developed for
the first time by Sushruta and the references
regarding tuvarakarasayana reflects about it.
 The pulp of tuvaraka is to be burnt in closed
vessel without letting out the smoke ( Antardhuma
method) and put.
A thorough review of SushrutaSamhita provides a
sound opinion that application of metals and minerals
are mentioned in this classic from the therapeutic
angle as well as other purpose.
AshtangaSangraha and AshtangaHridaya
 Internal administration of Parada was first time
mentioned in Ashtanga Sangraha Rasayana
Prakaran.
 Bhasmanirmanavidhi is mentioned in Ashtanga
Sangraha.
 For Lohamaran bhanupakvidhi is introduced.
 AstangaSangrahafirtly enumerates ghatimusaand
Andhamusa.
 The process of Dhatubhasma was conceived
during the time of Vriddhavagbhatta.
 For lohamarana Bhanupakavidhi hasintroduced.
 Shukravar dhanatm akkalpa is explained in detail
which contain Parada, Gandhaka and Shilajatu
etc.14
 Sikth, Sindoor, Tutha, Tarkshya are used in taila
form for treatment of vicharchika.
 Two tyes of Lauha – Tikshnalauha and Krishna
lauha has described.
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
@ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 5 | Jul-Aug 2018 Page: 49
 Ras, Veerya, Vipaka of various dhatu introduced
by vridhavagbhata.
 The credit of using visa in therapeutics once again
goes to vagbhatta.
Kautilya Arthshastra
Kautilya arthasastra written by Canakya, a great
Academic, Economical and Political master of Gupta
period. It may be composed in 4th
century B.C.
 In this period lohavidya is in its peak level of
development.
 Several references of use of metal and minerals
for purposes of preparation of utencils, armory
and some medicinal objectives found in
kautilyaArthashastra.15
 Sodhana and Mardavkara processes of dhatus
were mentioned.
 Identification of Dhatu and Ratnas are introduced.
 Seven types of Loha mentioned- Kalayas,
Tamravritta, Kansya, sisa,Trapu, Vakrintak, and
Aarkoot.
 Three sources for occerence of mukta mentioned-
Shankh, Shukti and Prakirna.
 Even though metals and minerals were used both
externally and internally for the preservation as
well as promotion of positive health and cure of
diseases.
 At that time three types of Suvarna used –
1. Jatroop( Native)
2. Rasavidha( from vedh of mercury)
3. Akarodbhav
 Suvarna made from Rasa i.e. Parada is mentioned
as Rasavidha.16
 This shows that even prior to his time this type of
gold was available in the market and people knew
the techniques of conversation of base metals into
noble metals with the help of mercury.
 For Suvarna shodhan they used siskam and for
suvarna vikrutikaran they used Hingula.
Varahmihira Period
Although he was the Acharya of Jyotishshastra, he
had the basic knowledge of Ayurveda and also of
Rasshastra.
 In his literature he explains all dhatu, Ratna,
Manhashila, Gairika etc.
 He again explains the Payanavidhi of shastra.
 He also made a shukravardhakkalpa which
includes Parada, Makshika, lohabhasma,
Gandhaka, shilajatu. This kalpa resembles the
Shukravardhak yoga of Ashtanga sangraha.17
Harsacarita
Harscarita of Banabhatta gives a long list of
companions and assistants of king Harsa this includes
physicians, alchemist, mineralogists, priests etc.
 Here mineralogy was an art it belonged to one of
the sixty four arts
 Its aim was to make some worthy minerals out of
some worthless ones i.e. through alchemy; the
term Jatarupaka for gold maks this clear.
 The knowledge of mineralogy was accomplished
through tantras and mantras.
Kubjikatantra
Manuscripts of this work were traced in ‘Nepal
library. It may be composed in 6th century A.D.
 It is mentioned that therapeutic action of Parada
increases due to incineration of it with sulphur for
six times.
 The procedure of transmutation of copper into
gold is mentioned in this book.
Development of Rasa Shastra in Medieval period
Nagarjuna: The systemic evolution of Rasa Shastra
took place during the time of Nagarjuna. In this period
number of most valuable Rasa preparations alongwith
their pharmaceutical processing techniques have
developed. He learned knowledge from Acharya
Sarabha in Nalanda Vidyapitha. He knows about
Mayurividya and krutrim Swarna Nimana from
parada.18
Acharya Gorakshanath: He made the Khechari
Gutika and Suvarnanirmanarthagutikakalpa.
Rasa Ratna Samucchaya: It is a well known
comprehensive treatise of Rasa Shastra. Scattered
knowledge of Rasaśāstra is well compiled
by Vāgbhaᚭa. It is the best available text
on Rasaśāstra which describes not only
pharmaceutical and therapeutical aspects but also
covers the eight branches of Ayurveda. It is a
compilation but has its own specialty and
consequence. 19
Rasa Hridaya Tantra: Rasa HridayaTantra is a
unique text among a huge number of rasa literatures,
which gives elaborate description of 18 special
mercurial processing techniques (Astadashaparada
Samskara).This manuscript is presented with a
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
@ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 5 | Jul-Aug 2018 Page: 50
guideline, how to make Mercury competent for
transmuting base metals into a noble one and to
produce therapeutic benefits with them.20
Ras Ratnakara: He explained krutim
Manikyanirmana and Indranil Nirmana in his book
RasRatnakara.
Anandakanda: This text gives an elaborate
description of Rasa Shastra. Dehavada as well as
Lohavada concept of Rasa Shastra has been described
in detail.
Development of Rasa Shastra in Modern Era
Bhaishajya Ratnavali: Bhaishajya Ratnavali is
written by Kavi Raj Govinda Das Sen composed in 18
th century AD. It is compiled book mainly from
Chakradutta, Rasendrasarasangraha, Charaka etc.
Paribhasha Prakarana, Mana Paribbhasa, various
Rasa dravya are described in detail. Yogas including
swarasa, kalka, kwath, vati, Bhasma and various
compound Herbal and Herbomineral preparations and
pathyaand apathyaare mentioned in detail for each
diseases .21
Rasatarangini: Rasatarangini is written by
Pranacharya Sadananda Sharma. It ia an authoritative
text on Rasa Shastra and contains all the detail of
various procedures involved in the drug preparations.
Acharya has named the chapters of the text as
Taranga. Total 24 Taranga and 3651 verses
encompasses Rasatarangini. Acharya Sadananda
Sharma has mentioned only those procedures which
are realistic and feasible in present scenario. He
mentioned some acids like sulphuric acid, sorakamla,
Lavanamla etc.22
Rasamritam: This book is written by Acharya Yadav
ji Trikamji in 1951.Rasamritam is the latest doctrine
in the field of Rasa Shastra which compiles the extract
of the older books and adopted some new and
contemporary concepts. The Practical aspects of this
text influence both the academicians as well as
physicians in large extent. Very systemic
classifications of materials are found in this text. It is
a literature of modern era where amalgamation of
modern chemistry and Rasa Shastra occurs, and also
incorporation of some unani drugs are found.23
Rasa yoga Sagar: Rasa yoga sagar is written by Shri
Hariprapannasharma in 1930. In this text various
formulations from different classics are collected. In
addition to this some new formulations are also
included.
Kupipakwa Rasa Nirmana Vigyana: This book
was written by Vaidya Harisharnananda. In this
treatise he mentioned various kupiakva rasa kalpas
and their methods of preparation. Swami
Harisharanand Vaidya has described 258
kupipakwarasayana in his text Kupiakava Rasa
NirmanaVigyana.
Ratna Dhatu Vigyan: This Granth is written by Shri
Badrinarayana shastri. In this book all gemstones
(Ratna and Upratna) and other Rasshatriyadravya
(Parada, Rasa, Uparasa) are described in detail. In
addition to this some upratna( Jaharmohra, Akika,
Yakuta) and some minerals like uranium, chromium,
chroyolite and Kelslite are briefly described
Discussion
History of Indian alchemy can be traced to pre vedic
period. The archaeological excavations at
Mohenjodaro and Harappa in the Indus valley have
brought to light that the people in ancient India were
possessing chemical knowledge as early as in the pre
historic period. In Vedic period single herbs were
used for medication. Minerals and animal substances
were also in use but no compound preparations were
prepared. Alchemy in India was started for the
preparation off a potion of life for imparting
immortality and later for the transmutation process for
converting ordinary metals into gold. Indian alchemy
derived its colour and flavour largely from tantric
cult. Then, in later centuries, all the previous
accumulated alchemial ideas were put to practical use
and a number of preparations of mercury and other
metals were evolved as helpful accessories in
medicine
Conclusion
Historically the drugs of mineral origin are in use
since ancient times in the therapeutics but during that
period their numbers were very much limited
probably on account of non development of suitable
and sophisticated pharmaceutical procedures,
techniques and processes necessary for their
conversion to suitable dosage forms. However since
the time of Nagarjuna ( 8th
and 9th
century A.D.) Who
is considered as ‘Father of Indian alchemy and metal
related Ayurvedic pharmaceutical sciences, the use of
mineral drugs have started to become more popular
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
@ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 5 | Jul-Aug 2018 Page: 51
and frequent in Alchemy and pharmaceutic-
otherapeutics. It is believed to have come into its
proper existence with its scientific classification and
documentation around 8th century. The main
foundation being the concept that the objective of the
science of mercury is not limited to Alchemy
(Dhaatuvaada) but also to maintain health and
strengthen the body for achieving Mukti .
REFERENCES
1. Angadi Ravindra, A Textbook of Rasashstra,
Chaukhamba Surbharti Prakashan Varanasi,
Chapter 1, pp: 2.
2. Khandal Santosh, Ras Bhaishajya Kalpana
Vigyan, Publication Scheme Jaipur, Reprint 2016,
pp:3
3. Khandal Santosh, Ras Bhaishajya Kalpana
Vigyan, Publication Scheme Jaipur, Reprint 2016,
pp:2
4. Tripathi Bramhananda, Charak Samhita Purvardh
Chaukhamba Surbharati Prakashann Varanasi,
reprint 2009, Ch. 1/71, pp:37
5. Tripathi Bramhananda, Charak Samhita Purvardh
Chaukhamba Surbharati Prakashann Varanasi,
reprint 2009, Charaka Sutra sthan 1/18-19, pp:116
6. Tripathi Bramhananda, Charak Samhita Purvardh
Chaukhamba Surbharati Prakashann Varanasi,
reprint 2009, Charaka SharirSthan 8/119, pp:940
7. Shastri Kashinnath Charaka Samhita Uttarardh,
Chaukhambha Bharati Academy Reprint
2013,Charaka Chikitsa 1/3-23, pp:37
8. Shastri Kashinnath Charaka Samhita Uttarardh,
Chaukhambha Bharati Academy Reprint
2013,CharakaChikitsa 4/79, pp:190
9. Shastri Kashinnath, Charaka Samhita Uttarardh,
Chaukhambha Bharati Academy Reprint
2013,Charaka Chikitsa 23/239, pp:666
10. Shastri Ambikadutta, Sushruta Samhita
Purvardha. Chaukhambha Sanskrit Sannsthan
Varanasi, Reprint 2012, Sushruta Sutra 38/63,
pp:188
11. Shastri Ambikadutta, Sushruta Samhita
Purvardha. Chaukhambha Sanskrit Sannsthan
Varanasi, Reprint 2012, SushrutaChikitsa10/11,
pp:72
12. Shastri Ambikadutta, Sushruta Samhita
Uttarardha. Chaukhambha Sanskrit Sannsthan
Varanasi, Reprint 2012, Sushruta Uttartantra
44/21, pp:373
13. Shastri Ambikadutta, Sushruta Samhita
Purvardha. Chaukhambha Sanskrit Sannsthan
Varanasi, Reprint 2012, SushrutaSharira 10/17,
pp:103
14. Mishra Siddhinandan, Ayurvediya Rasa Shastra,
Chaukhambha Orientalia Varanasi, Reprint 2009,
pp:14
15. Mishra Siddhinandan, Ayurvediya Rasa Shastra,
Chaukhambha Orientalia Varanasi, Reprint 2009,
pp: 17.
16. Mishra Siddhinandan, Ayurvediya Rasa Shastra,
Chaukhambha Orientalia Varanasi, Reprint 2009,
pp: 18
17. Mishra Siddhinandan, Ayurvediya Rasa Shastra,
Chaukhambha Orientalia Varanasi, Reprint 2009,
pp: 19
18. Jha Channdrahushan, Ayurvediya Rasa Shastra,
Chaukhamba Surbharati Prakashan Varanasi,
Reprint 2007, pp: 11.
19. Jha Channdrahushan, Ayurvediya Rasa Shastra,
Chaukhamba Surbharati Prakashan Varanasi,
Reprint 2007, pp:49.
20. Jha Channdrahushan, Ayurvediya Rasa Shastra,
Chaukhamba Surbharati Prakashan Varanasi,
Reprint 2007, pp: 45.
21. Jha Channdrahushan, Ayurvediya Rasa Shastra,
Chaukhamba Surbharati Prakashan Varanasi,
Reprint 2007, pp: 54.
22. Jha Channdrahushan, Ayurvediya Rasa Shastra,
Chaukhamba Surbharati Prakashan Varanasi,
Reprint 2007, pp: 55.
23. Jha Channdrahushan, Ayurvediya Rasa Shastra,
Chaukhamba Surbharati Prakashan Varanasi,
Reprint 2007, pp:57

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Chronological Development of Rasa Shastra

  • 1. @ IJTSRD | Available Online @ www.ijtsrd.com ISSN No: 2456 International Research Chronological Development Dr. Gajendra Kumar Sahu 1,2 MD Scholar PG Department of Rasshastra and Bhaishajyakalpana ABSTRACT Rasa shastra is a most important and popular branch of Ayurveda It deals with the knowledge related to alchemy( Lohavedh) and Ayurvedic Pharmaceutics specially connected to the drugs of mineral with a view to remove poverty from the world and to strengthen the body and also to prevent their ageing process. History of Rasa Shastra can be traced in pre vedic period where metals are successfully employed in treatment of various diseases. Its development was rapid after Lord Buddha and the influence of the philosophy of Ahimsa. This was the era when Rasa Shastra flourished tremendously. It was recognized as a medical science with an independent philosophical background in 14th century, by Madhavacharya in his book Sarva Darsana Samgraha. Considering the importance of this discipline in Ayurvedic therapeutics and the fact that there is dearth of comprehensive review on the subject an attempt has been made in this review to provide a brief but all encompassing coverage of different aspects related to it. Keywords: Alchemy, Ahimsa, Lohavedh INTRODUCTION Etymologically the word “Rasa” is use the metal Mercury, also known as quicksilver. The word “Shastra” means knowledge or sacred The term Rasa shastra, therefore could be translated as the ‘science of mercury’. Rasshastra or the Ayurvedic alchemy is an important branch of Ayurvedic pharmacology which deals with the metals, minerals the gemstones, animal products and herb ingredients, highly medicinal co mounds were formulated for rejuvenation, the cure for chronic @ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 5 | Jul-Aug ISSN No: 2456 - 6470 | www.ijtsrd.com | Volume International Journal of Trend in Scientific Research and Development (IJTSRD) International Open Access Journal Chronological Development of Rasa Shastra Dr. Gajendra Kumar Sahu1 , Dr. Kavita2 , Dr. S. M. Parhate3 , K. S MD Scholar, 3 Professor and HOD, 4 Reader of Rasshastra and Bhaishajyakalpana Govt. Ayurvedic C Raipur, Chhattisgarh, India Rasa shastra is a most important and popular branch of Ayurveda It deals with the knowledge related to alchemy( Lohavedh) and Ayurvedic Pharmaceutics specially connected to the drugs of mineral origin with a view to remove poverty from the world and to strengthen the body and also to prevent their ageing process. History of Rasa Shastra can be traced in pre vedic period where metals are successfully employed development was rapid after Lord Buddha and the influence of the This was the era when Rasa Shastra flourished tremendously. It was recognized as a medical science with an independent philosophical vacharya in his Considering the importance of this discipline in Ayurvedic therapeutics and the fact that there is dearth of comprehensive review on the subject an attempt has been made in this review to provide a brief but all encompassing coverage of different aspects related to Etymologically the word “Rasa” is used to describe , also known as quicksilver. The s knowledge or sacred scripture. therefore could be translated as the ‘science of mercury’. Rasshastra or the Ayurvedic alchemy is an important branch of Ayurvedic pharmacology which deals with the metals, animal products and herbal mounds were formulated for rejuvenation, the cure for chronic disease and ultimately life extension. dravya have the following three characteristic attributes: instant effectiveness, requirement of very small doses and extensive therapeutic utility irrespective of constitutional variation. The origin of Rasa sastra has its roots in the Indian alchemy Alchemy was a form of chemistry studied in the medieval period, in which people tried to discover different ways to change ordinary metals into gold. This practice went on for centuries, yielding some of the significant findings in the field of alchemy. Vedic Kala  Rigveda reveals that copper, gold, Iron and some other metals and minerals have been used in that period.2  Rigveda refers to Asvins substituting the lost leg of Vishala by a thigh made of iron.  Yajurveda enumerated a list of metals &minerls Ayas, Hiranya, Syam (copper), Trapu (Tin).  According to a quotation in Yajurveda Swarna is useful in improving longevity, lusture, Strength.  In Atharvveda Hiranyadarshanphala and its internal use are mentioned  Chandogya Upanishad – medicine.  Transmutation of lower metals into gold has been described in Taittariyabramhana.  As per Manusmriti During the birth ritual of a baby Swarnaprasana is indicated.  The description of metals like Swarna, Rajat etc. and precious stones like Manikya, etc. is available in Garuda Purana, Agni Purana, and Devi bhagvat. 2018 Page: 47 6470 | www.ijtsrd.com | Volume - 2 | Issue – 5 Scientific (IJTSRD) International Open Access Journal f Rasa Shastra S Karbhal4 College, disease and ultimately life extension.1 The Rasa dravya have the following three characteristic attributes: instant effectiveness, requirement of very ll doses and extensive therapeutic utility irrespective of constitutional variation. The origin of its roots in the Indian alchemy. Alchemy was a form of chemistry studied in the medieval period, in which people tried to discover ways to change ordinary metals into gold. This practice went on for centuries, yielding some of the significant findings in the field of alchemy. Rigveda reveals that copper, gold, Iron and some other metals and minerals have been used in that Rigveda refers to Asvins substituting the lost leg of Vishala by a thigh made of iron. Yajurveda enumerated a list of metals &minerls – Ayas, Hiranya, Syam (copper), Loha, Sisa (Lead), According to a quotation in Yajurveda Swarna is seful in improving longevity, lusture, Strength.3 Hiranyadarshanphala and its internal use are mentioned – Tikshnaloha used as Transmutation of lower metals into gold has been described in Taittariyabramhana. per Manusmriti During the birth ritual of a baby Swarnaprasana is indicated. The description of metals like Swarna, Rajat etc. and precious stones like Manikya, etc. is available in Garuda Purana, Agni Purana, and Devi bhagvat.
  • 2. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 @ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 5 | Jul-Aug 2018 Page: 48 CharakaSamhita Caraka has classified drugs into three categories – 1. Sthavar 2. Jangam 3. Bhaum The third category includes gold, iron, copper, tin etc.4  Manhshila, Haratala, Kasis, are used for external application for purpose of external application.  Shodhana of Parthivdravya are mentioned in charakasamhita.5  Suvarna and Rouya are used for purose of PunsavanSamsakara.6  Lohadi Rasayana is indicated for Rasayana Karma7  Vaidurya, Mukta, Manibhasma, Gairika, Shankha, Suvarnabhasma has used in udakakalpana for Raktaittachikitsa.8  There is no direct reference of Parad is mentioned in Charak Samhita. But in charakakushtha-chikitsa adhyay the word “Ras” is used.  Different types of Loha, Tapya, Adrija, Rouya, Makskika etc. has used in variety of yogas for Panduchikitsa.  Mukta, Praval, Vaidurya , Shankh, Shatika, Anjana, Gandhaka has used in Shwasvyadhi as Muktadyachurna with Madhu and Sarpi.  Tamra used in garavisha for vamana and suvarna with Madhuasvishagna yoga.9  Vajra, Markata, Vishamushika, vaidurya are used for sarpadanshanivaran.  Manahashila used as pradhamannasyain kaphajpratishyay.  Pitakchurna (Manhshila, Hartala, Yavakshara, Saindhav has used in Pitakchurna to treat mukharoga.  We see that Dhatus were administered in the form of powder (Raja) only and the concept of bhasmas was not developed during the classical age. Sushruta Samhita In this Samhita also references of Theraeutic applications of mineral and metallic substances are found abundantly.  Trapvadigana and usakadigana are described, various dhatus are mentioned in these gana.  Several Yantra and Shastra used in surgical process are made of different kinds of metals or alloys.  Ayaskriti is the specific contribution of Sushrutasamhita.11  Surprisingly external application of mercury is also evident in Sushruta Samhita.  Acharya Sushruta mention of pakas namely Sthalipaka. etc.  Dhatuvish – Phenashma and Hartala were first time introduced in Sushruta Samhita.  Internal administration of Anjana is first time indicated in Sushruta Samhita.  Various Dhatus are mentioned for internal administration in Dravya Sangrahniya adhyay.  Two bhedas of lauha is described in SushrutaSamhita. Tikshnalauhaand kala lauha.  Vibhitakkashtha is used for burning of Mandur.12  Gandhaka is used in Mahavajrataila for kushthachikitsa.  SwarnaPrashan is indicated in new born child.13  The word bhasma mentioned in Sushrutasamhita (Sutra 2 & Kalpa 6) only the ash of vegetable drugs.  The concept of Puta appears to be developed for the first time by Sushruta and the references regarding tuvarakarasayana reflects about it.  The pulp of tuvaraka is to be burnt in closed vessel without letting out the smoke ( Antardhuma method) and put. A thorough review of SushrutaSamhita provides a sound opinion that application of metals and minerals are mentioned in this classic from the therapeutic angle as well as other purpose. AshtangaSangraha and AshtangaHridaya  Internal administration of Parada was first time mentioned in Ashtanga Sangraha Rasayana Prakaran.  Bhasmanirmanavidhi is mentioned in Ashtanga Sangraha.  For Lohamaran bhanupakvidhi is introduced.  AstangaSangrahafirtly enumerates ghatimusaand Andhamusa.  The process of Dhatubhasma was conceived during the time of Vriddhavagbhatta.  For lohamarana Bhanupakavidhi hasintroduced.  Shukravar dhanatm akkalpa is explained in detail which contain Parada, Gandhaka and Shilajatu etc.14  Sikth, Sindoor, Tutha, Tarkshya are used in taila form for treatment of vicharchika.  Two tyes of Lauha – Tikshnalauha and Krishna lauha has described.
  • 3. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 @ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 5 | Jul-Aug 2018 Page: 49  Ras, Veerya, Vipaka of various dhatu introduced by vridhavagbhata.  The credit of using visa in therapeutics once again goes to vagbhatta. Kautilya Arthshastra Kautilya arthasastra written by Canakya, a great Academic, Economical and Political master of Gupta period. It may be composed in 4th century B.C.  In this period lohavidya is in its peak level of development.  Several references of use of metal and minerals for purposes of preparation of utencils, armory and some medicinal objectives found in kautilyaArthashastra.15  Sodhana and Mardavkara processes of dhatus were mentioned.  Identification of Dhatu and Ratnas are introduced.  Seven types of Loha mentioned- Kalayas, Tamravritta, Kansya, sisa,Trapu, Vakrintak, and Aarkoot.  Three sources for occerence of mukta mentioned- Shankh, Shukti and Prakirna.  Even though metals and minerals were used both externally and internally for the preservation as well as promotion of positive health and cure of diseases.  At that time three types of Suvarna used – 1. Jatroop( Native) 2. Rasavidha( from vedh of mercury) 3. Akarodbhav  Suvarna made from Rasa i.e. Parada is mentioned as Rasavidha.16  This shows that even prior to his time this type of gold was available in the market and people knew the techniques of conversation of base metals into noble metals with the help of mercury.  For Suvarna shodhan they used siskam and for suvarna vikrutikaran they used Hingula. Varahmihira Period Although he was the Acharya of Jyotishshastra, he had the basic knowledge of Ayurveda and also of Rasshastra.  In his literature he explains all dhatu, Ratna, Manhashila, Gairika etc.  He again explains the Payanavidhi of shastra.  He also made a shukravardhakkalpa which includes Parada, Makshika, lohabhasma, Gandhaka, shilajatu. This kalpa resembles the Shukravardhak yoga of Ashtanga sangraha.17 Harsacarita Harscarita of Banabhatta gives a long list of companions and assistants of king Harsa this includes physicians, alchemist, mineralogists, priests etc.  Here mineralogy was an art it belonged to one of the sixty four arts  Its aim was to make some worthy minerals out of some worthless ones i.e. through alchemy; the term Jatarupaka for gold maks this clear.  The knowledge of mineralogy was accomplished through tantras and mantras. Kubjikatantra Manuscripts of this work were traced in ‘Nepal library. It may be composed in 6th century A.D.  It is mentioned that therapeutic action of Parada increases due to incineration of it with sulphur for six times.  The procedure of transmutation of copper into gold is mentioned in this book. Development of Rasa Shastra in Medieval period Nagarjuna: The systemic evolution of Rasa Shastra took place during the time of Nagarjuna. In this period number of most valuable Rasa preparations alongwith their pharmaceutical processing techniques have developed. He learned knowledge from Acharya Sarabha in Nalanda Vidyapitha. He knows about Mayurividya and krutrim Swarna Nimana from parada.18 Acharya Gorakshanath: He made the Khechari Gutika and Suvarnanirmanarthagutikakalpa. Rasa Ratna Samucchaya: It is a well known comprehensive treatise of Rasa Shastra. Scattered knowledge of Rasaśāstra is well compiled by Vāgbhaáš­a. It is the best available text on Rasaśāstra which describes not only pharmaceutical and therapeutical aspects but also covers the eight branches of Ayurveda. It is a compilation but has its own specialty and consequence. 19 Rasa Hridaya Tantra: Rasa HridayaTantra is a unique text among a huge number of rasa literatures, which gives elaborate description of 18 special mercurial processing techniques (Astadashaparada Samskara).This manuscript is presented with a
  • 4. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 @ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 5 | Jul-Aug 2018 Page: 50 guideline, how to make Mercury competent for transmuting base metals into a noble one and to produce therapeutic benefits with them.20 Ras Ratnakara: He explained krutim Manikyanirmana and Indranil Nirmana in his book RasRatnakara. Anandakanda: This text gives an elaborate description of Rasa Shastra. Dehavada as well as Lohavada concept of Rasa Shastra has been described in detail. Development of Rasa Shastra in Modern Era Bhaishajya Ratnavali: Bhaishajya Ratnavali is written by Kavi Raj Govinda Das Sen composed in 18 th century AD. It is compiled book mainly from Chakradutta, Rasendrasarasangraha, Charaka etc. Paribhasha Prakarana, Mana Paribbhasa, various Rasa dravya are described in detail. Yogas including swarasa, kalka, kwath, vati, Bhasma and various compound Herbal and Herbomineral preparations and pathyaand apathyaare mentioned in detail for each diseases .21 Rasatarangini: Rasatarangini is written by Pranacharya Sadananda Sharma. It ia an authoritative text on Rasa Shastra and contains all the detail of various procedures involved in the drug preparations. Acharya has named the chapters of the text as Taranga. Total 24 Taranga and 3651 verses encompasses Rasatarangini. Acharya Sadananda Sharma has mentioned only those procedures which are realistic and feasible in present scenario. He mentioned some acids like sulphuric acid, sorakamla, Lavanamla etc.22 Rasamritam: This book is written by Acharya Yadav ji Trikamji in 1951.Rasamritam is the latest doctrine in the field of Rasa Shastra which compiles the extract of the older books and adopted some new and contemporary concepts. The Practical aspects of this text influence both the academicians as well as physicians in large extent. Very systemic classifications of materials are found in this text. It is a literature of modern era where amalgamation of modern chemistry and Rasa Shastra occurs, and also incorporation of some unani drugs are found.23 Rasa yoga Sagar: Rasa yoga sagar is written by Shri Hariprapannasharma in 1930. In this text various formulations from different classics are collected. In addition to this some new formulations are also included. Kupipakwa Rasa Nirmana Vigyana: This book was written by Vaidya Harisharnananda. In this treatise he mentioned various kupiakva rasa kalpas and their methods of preparation. Swami Harisharanand Vaidya has described 258 kupipakwarasayana in his text Kupiakava Rasa NirmanaVigyana. Ratna Dhatu Vigyan: This Granth is written by Shri Badrinarayana shastri. In this book all gemstones (Ratna and Upratna) and other Rasshatriyadravya (Parada, Rasa, Uparasa) are described in detail. In addition to this some upratna( Jaharmohra, Akika, Yakuta) and some minerals like uranium, chromium, chroyolite and Kelslite are briefly described Discussion History of Indian alchemy can be traced to pre vedic period. The archaeological excavations at Mohenjodaro and Harappa in the Indus valley have brought to light that the people in ancient India were possessing chemical knowledge as early as in the pre historic period. In Vedic period single herbs were used for medication. Minerals and animal substances were also in use but no compound preparations were prepared. Alchemy in India was started for the preparation off a potion of life for imparting immortality and later for the transmutation process for converting ordinary metals into gold. Indian alchemy derived its colour and flavour largely from tantric cult. Then, in later centuries, all the previous accumulated alchemial ideas were put to practical use and a number of preparations of mercury and other metals were evolved as helpful accessories in medicine Conclusion Historically the drugs of mineral origin are in use since ancient times in the therapeutics but during that period their numbers were very much limited probably on account of non development of suitable and sophisticated pharmaceutical procedures, techniques and processes necessary for their conversion to suitable dosage forms. However since the time of Nagarjuna ( 8th and 9th century A.D.) Who is considered as ‘Father of Indian alchemy and metal related Ayurvedic pharmaceutical sciences, the use of mineral drugs have started to become more popular
  • 5. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 @ IJTSRD | Available Online @ www.ijtsrd.com | Volume – 2 | Issue – 5 | Jul-Aug 2018 Page: 51 and frequent in Alchemy and pharmaceutic- otherapeutics. It is believed to have come into its proper existence with its scientific classification and documentation around 8th century. The main foundation being the concept that the objective of the science of mercury is not limited to Alchemy (Dhaatuvaada) but also to maintain health and strengthen the body for achieving Mukti . REFERENCES 1. Angadi Ravindra, A Textbook of Rasashstra, Chaukhamba Surbharti Prakashan Varanasi, Chapter 1, pp: 2. 2. Khandal Santosh, Ras Bhaishajya Kalpana Vigyan, Publication Scheme Jaipur, Reprint 2016, pp:3 3. Khandal Santosh, Ras Bhaishajya Kalpana Vigyan, Publication Scheme Jaipur, Reprint 2016, pp:2 4. Tripathi Bramhananda, Charak Samhita Purvardh Chaukhamba Surbharati Prakashann Varanasi, reprint 2009, Ch. 1/71, pp:37 5. Tripathi Bramhananda, Charak Samhita Purvardh Chaukhamba Surbharati Prakashann Varanasi, reprint 2009, Charaka Sutra sthan 1/18-19, pp:116 6. Tripathi Bramhananda, Charak Samhita Purvardh Chaukhamba Surbharati Prakashann Varanasi, reprint 2009, Charaka SharirSthan 8/119, pp:940 7. Shastri Kashinnath Charaka Samhita Uttarardh, Chaukhambha Bharati Academy Reprint 2013,Charaka Chikitsa 1/3-23, pp:37 8. Shastri Kashinnath Charaka Samhita Uttarardh, Chaukhambha Bharati Academy Reprint 2013,CharakaChikitsa 4/79, pp:190 9. Shastri Kashinnath, Charaka Samhita Uttarardh, Chaukhambha Bharati Academy Reprint 2013,Charaka Chikitsa 23/239, pp:666 10. Shastri Ambikadutta, Sushruta Samhita Purvardha. Chaukhambha Sanskrit Sannsthan Varanasi, Reprint 2012, Sushruta Sutra 38/63, pp:188 11. Shastri Ambikadutta, Sushruta Samhita Purvardha. Chaukhambha Sanskrit Sannsthan Varanasi, Reprint 2012, SushrutaChikitsa10/11, pp:72 12. Shastri Ambikadutta, Sushruta Samhita Uttarardha. Chaukhambha Sanskrit Sannsthan Varanasi, Reprint 2012, Sushruta Uttartantra 44/21, pp:373 13. Shastri Ambikadutta, Sushruta Samhita Purvardha. Chaukhambha Sanskrit Sannsthan Varanasi, Reprint 2012, SushrutaSharira 10/17, pp:103 14. Mishra Siddhinandan, Ayurvediya Rasa Shastra, Chaukhambha Orientalia Varanasi, Reprint 2009, pp:14 15. Mishra Siddhinandan, Ayurvediya Rasa Shastra, Chaukhambha Orientalia Varanasi, Reprint 2009, pp: 17. 16. Mishra Siddhinandan, Ayurvediya Rasa Shastra, Chaukhambha Orientalia Varanasi, Reprint 2009, pp: 18 17. Mishra Siddhinandan, Ayurvediya Rasa Shastra, Chaukhambha Orientalia Varanasi, Reprint 2009, pp: 19 18. Jha Channdrahushan, Ayurvediya Rasa Shastra, Chaukhamba Surbharati Prakashan Varanasi, Reprint 2007, pp: 11. 19. Jha Channdrahushan, Ayurvediya Rasa Shastra, Chaukhamba Surbharati Prakashan Varanasi, Reprint 2007, pp:49. 20. Jha Channdrahushan, Ayurvediya Rasa Shastra, Chaukhamba Surbharati Prakashan Varanasi, Reprint 2007, pp: 45. 21. Jha Channdrahushan, Ayurvediya Rasa Shastra, Chaukhamba Surbharati Prakashan Varanasi, Reprint 2007, pp: 54. 22. Jha Channdrahushan, Ayurvediya Rasa Shastra, Chaukhamba Surbharati Prakashan Varanasi, Reprint 2007, pp: 55. 23. Jha Channdrahushan, Ayurvediya Rasa Shastra, Chaukhamba Surbharati Prakashan Varanasi, Reprint 2007, pp:57