This paper presents a comparative analysis of two multilevel inverter topologies—diode clamped multilevel inverter (DCMLI) and cascaded H-bridge multilevel inverter (CHMLI)—utilizing the sinusoidal pulse width modulation (SPWM) technique for driving a three-phase induction motor. The study develops models and simulations in MATLAB/Simulink to evaluate the performance of 5-level and 7-level configurations, focusing on total harmonic distortion (THD) and modulation strategies. Key findings indicate that multilevel inverters offer advantages in reducing harmonic distortion and improving power quality for medium-voltage applications.