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Viral conjunctivitis- Adeno virus
Anup Muni Bajracharya
AdenoViral conjunctivitis
 Adenoviral conjunctivitis, also known as "pink eye is a common, self-limiting
condition that typically is caused by adenovirus.
 These viruses belong to the Adenoviridae family
 It is caused by various serotypes of adenoviruses. There are more than 50
known strains of this virus.
 Adeno virus can cause a range of illnesses, including respiratory infections,
gastrointestinal infections, and conjunctivitis.
Human adenoviruses
 Human adenoviruses (HADVs) are non-envelope, icosahedral, double-stranded DNA
viruses and are classified within the family Adenoviridae, genus Mastadenovirus, and
are further divided into seven species (A–G).
 Adenoviruses can cause an array of clinical diseases, including conjunctivitis, respiratory
disease, hemorrhagic cystitis and gastroenteritis.
 Several adenoviruses including HAdV-8, HAdV-19 and HADV-37 (in HAdV-D) are
responsible from severe and contagious Epidemic keratoconjunctivitis which can be
related to a nosocomial infection or community acquired
Symptoms
 Redness: The whites of the eyes become red and irritated.
 Watery Discharge: Excessive tearing and watery discharge from the eyes.
 Itching: The eyes may feel itchy and uncomfortable.
 Foreign Body Sensation: Patients may feel as if there's something gritty or
foreign in the eye.
 Swelling: Swelling of the eyelids and conjunctiva.
 Light Sensitivity: Increased sensitivity to light (photophobia).
 Blurred Vision: Vision may be blurred due to the discharge and irritation.
Transmission
 Adenoviral conjunctivitis is highly contagious and can spread through:
 Direct Contact: Touching an infected person's eye or secretions, then
touching one's own eyes.
 Indirect Contact: Touching contaminated surfaces (doorknobs, towels) and
then touching the eyes.
 Patients should avoid touching their eyes, shaking hands, and sharing
towels, napkins, pillow cases, and other fomites, among other activities.
 Transmission may occur through accidental inoculation of viral particles
from the patient's hands or by direct eye contact with infected upper
respiratory droplets, fomites, or contaminated swimming pools.
 The infection usually resolves spontaneously within 2-4 weeks.
Treatment
 Adenoviral conjunctivitis is usually a self-limiting condition, and symptoms
often resolve on their own within a week or two.
 There is no specific antiviral treatment for adenoviral conjunctivitis.
Supportive care includes:
 Artificial Tears: Lubricating eye drops to alleviate discomfort.
 Cold Compresses: Applying cool compresses to reduce swelling and
soothe the eyes.
 Hygiene: Frequent hand washing and avoiding touching the eyes can help
prevent spreading the infection.
 Isolation: Infected individuals should avoid close contact with others,
especially in settings like schools or daycare centers.
Prevention
 Preventive measures include:
 Hand Hygiene: Frequent hand washing with soap and water, especially after
touching the eyes or coming into contact with potentially contaminated
surfaces.
 Avoiding Close Contact: Limit close contact with infected individuals, especially
in crowded settings.
 Good Respiratory Hygiene: Covering the mouth and nose when sneezing or
coughing to prevent respiratory droplet transmission.
 Avoiding sharing personal items such as towels, pillowcases, and eye makeup.
 Practicing good hygiene in public spaces, such as regularly disinfecting surfaces
that may come into contact with hands and eyes.
 Isolating infected individuals, especially in places like schools or daycare
centers, to prevent outbreaks.
conjunctivitis.pdf
conjunctivitis.pdf
Reference
 Shafiei K, Makvandi M, Teimoori A, Samarbafzadeh A, Khataminia G, Jalilian
S, Neisi N, Makvandi K, Haj MS. Frequency of adenovirus serotype 8 in
patients with Keratoconjunctivitis, in Ahvaz, Iran. Iran J Microbiol. 2019
Apr;11(2):129-136. PMID: 31341567; PMCID: PMC6635320.
 https://emedicine.medscape.com/article/1191370-overview?form=fpf
 https://www.healthline.com/health/eye-health/adenoviral-conjunctivitis

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conjunctivitis.pdf

  • 1. Viral conjunctivitis- Adeno virus Anup Muni Bajracharya
  • 2. AdenoViral conjunctivitis  Adenoviral conjunctivitis, also known as "pink eye is a common, self-limiting condition that typically is caused by adenovirus.  These viruses belong to the Adenoviridae family  It is caused by various serotypes of adenoviruses. There are more than 50 known strains of this virus.  Adeno virus can cause a range of illnesses, including respiratory infections, gastrointestinal infections, and conjunctivitis.
  • 3. Human adenoviruses  Human adenoviruses (HADVs) are non-envelope, icosahedral, double-stranded DNA viruses and are classified within the family Adenoviridae, genus Mastadenovirus, and are further divided into seven species (A–G).  Adenoviruses can cause an array of clinical diseases, including conjunctivitis, respiratory disease, hemorrhagic cystitis and gastroenteritis.  Several adenoviruses including HAdV-8, HAdV-19 and HADV-37 (in HAdV-D) are responsible from severe and contagious Epidemic keratoconjunctivitis which can be related to a nosocomial infection or community acquired
  • 4. Symptoms  Redness: The whites of the eyes become red and irritated.  Watery Discharge: Excessive tearing and watery discharge from the eyes.  Itching: The eyes may feel itchy and uncomfortable.  Foreign Body Sensation: Patients may feel as if there's something gritty or foreign in the eye.  Swelling: Swelling of the eyelids and conjunctiva.  Light Sensitivity: Increased sensitivity to light (photophobia).  Blurred Vision: Vision may be blurred due to the discharge and irritation.
  • 5. Transmission  Adenoviral conjunctivitis is highly contagious and can spread through:  Direct Contact: Touching an infected person's eye or secretions, then touching one's own eyes.  Indirect Contact: Touching contaminated surfaces (doorknobs, towels) and then touching the eyes.  Patients should avoid touching their eyes, shaking hands, and sharing towels, napkins, pillow cases, and other fomites, among other activities.  Transmission may occur through accidental inoculation of viral particles from the patient's hands or by direct eye contact with infected upper respiratory droplets, fomites, or contaminated swimming pools.  The infection usually resolves spontaneously within 2-4 weeks.
  • 6. Treatment  Adenoviral conjunctivitis is usually a self-limiting condition, and symptoms often resolve on their own within a week or two.  There is no specific antiviral treatment for adenoviral conjunctivitis. Supportive care includes:  Artificial Tears: Lubricating eye drops to alleviate discomfort.  Cold Compresses: Applying cool compresses to reduce swelling and soothe the eyes.  Hygiene: Frequent hand washing and avoiding touching the eyes can help prevent spreading the infection.  Isolation: Infected individuals should avoid close contact with others, especially in settings like schools or daycare centers.
  • 7. Prevention  Preventive measures include:  Hand Hygiene: Frequent hand washing with soap and water, especially after touching the eyes or coming into contact with potentially contaminated surfaces.  Avoiding Close Contact: Limit close contact with infected individuals, especially in crowded settings.  Good Respiratory Hygiene: Covering the mouth and nose when sneezing or coughing to prevent respiratory droplet transmission.  Avoiding sharing personal items such as towels, pillowcases, and eye makeup.  Practicing good hygiene in public spaces, such as regularly disinfecting surfaces that may come into contact with hands and eyes.  Isolating infected individuals, especially in places like schools or daycare centers, to prevent outbreaks.
  • 10. Reference  Shafiei K, Makvandi M, Teimoori A, Samarbafzadeh A, Khataminia G, Jalilian S, Neisi N, Makvandi K, Haj MS. Frequency of adenovirus serotype 8 in patients with Keratoconjunctivitis, in Ahvaz, Iran. Iran J Microbiol. 2019 Apr;11(2):129-136. PMID: 31341567; PMCID: PMC6635320.  https://emedicine.medscape.com/article/1191370-overview?form=fpf  https://www.healthline.com/health/eye-health/adenoviral-conjunctivitis