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William	Hersh1,	David	A.	Dorr1,2,	Melissa	Haendel1,3,	Nicole	Vasilevsky1,3,	Bjorn	Pederson1,		
Jackie	Wirz1,3,	Shannon	McWeeney1	
1Department	of	Medical	Informatics	and	Clinical	Epidemiology,	2Department	of	Medicine,	3Ontology	Development	Group,	Library	
Oregon	Health	&	Science	University,	Portland,	OR	
Students felt the course
Acknowledgements	
This	work	is	supported	by	NIH	Grants	1R25EB020379-01	
and		1R25GM114820-01.	
Skills Course Topics	Why?	
Course Offerings	
Defining The Problem Wrangling Data
Methods, Tools And
Analysis
Scientific
Communication
Data Identification And Resources
…
?
v  Problems	amenable	to	
analytics		
v  Importance	of	question	
v  Team	deinitions	
v  Scope	
v  When	we	do	this	wrong:	
methods	don't	match	
v  Finding	the	right	data	
v  Search	methods	
v  Use	of	metadata	
v  Data	management	
v Exploratory	Data	Analysis	
v Data	Dictionary	
v As	you	touch	data,	what	
can	go	wrong?	
v  Visualization	
v  Matching	algorithms	to	
problems	
v  Reporting	Findings	and	Limitations	
v  Giving	“Elevator	Speech”		on	ideas	of	
how	to	approach	problem	
v  Critique	of	related	problem	
Major	challenge:	how	to	manage,	analyze	and	interpret	vast	
amounts	of	data	being	generated	in	biomedical	research	
	
One	goal	of	NIH	Big	Data	to	Knowledge	(BD2K)	initiative:		
provide	training	for	students	and	researchers	to	address	
this	
	
Research	team	in	the	Department	of	Medical	Informatics	
and	Clinical	Epidemiology		(DMICE)	is	developing	skills	
courses	
Approach	
Intro	Course	
Data	After	
Dark	
OERs	and	courses	connect	the	dots	that	help	
researchers	understand	how	to	apply	data	science	
techniques	in	the	context	of	their	whole	research	life	
cycle	
§  Skills	course	and	OER	topics	are	aimed	to	ill	speciic	
gaps	
§  Teaching	students	how	to	ask	the	question	and	follow	
through	
① Develop	Open	Educational	Resources		
(OERS)	
② Teach	Skills	Courses	
19	|	Semantic	data	interoperability		
20	|	Semantic	Web	data		
21	|	Context-based	selection	of	data		
22	|	Translating	the	Question		
23	|	Implications	of	Provenance	and	
Pre-processing	
24	|	Data	tells	a	story		
25	|	Choice	of	Algorithms	and	
Algorithm	Dynamics		
26	|	Statistical	Signiicance,	P-hacking	
and	Multiple-testing		
27	|	Displaying	Conidence	and	
Uncertainty		
28	|	Visualization	and	Interpretation		
29	|	Replication,	Validation	and	the	
spectrum	of	Reproducibility	
30	|	Regulatory	Issues	in	Big	Data	for	
Genomics	and	Health		
31	|	Hosting	data	dissemination	and	
data	stewardship	workshops		
32	|	Guidelines	for	reporting,	
publications,	and	data	sharing	
OER Modules	
Challenges	
Scope
Images
Style
Dissemination
How	to	scope	generic	curricula	
for	different	levels	of	users	
How	to	translate	diverse	
teaching	styles	into	general	
materials	
How	to	maximize	
dissemination	while	protecting	
intellectual	property	
How	to	incorporate	images	
and	other	copyrighted	
materials	into	open	
resources	
Available at:	
http://skynet.ohsu.edu/bd2k	
Advanced	
Course	
§  Week	long	course	in	Summer	2015	
§  Offered	to	interns	and	undergraduates	
§  Taught	basics	of	data	science	in	the		context	
of	the	research	life	cycle	
§  Two-evening	course	in	January	2016		
§  Offered	to	OHSU	students,	staff	and	faculty	
§  Taught	basics	of	data	science	
§  Four-evening	course	to	be	offered	in	May	
2016		
§  Offered	to	OHSU	students,	staff	and	faculty	
§  Teach	advanced	topics	in	of	data	science	
01	|	Biomedical	Big	Data	Science	
02	|	Introduction	to	Big	Data	in	Biology	
and	Medicine		
03	|	Ethical	Issues	in	Use	of	Big	Data		
04	|	Terminology	of	Biomedical,	
Clinical,	and	Translational	
Research		
05	|	Computing	Concepts	for	Big	Data		
06	|	Clinical	Data	and	Standards	
Related	to	Big	Data		
07	|	Basic	Research	Data	Standards		
08	|	Public	Health	and	Big	Data		
09	|	Team	Science		
10	|	Secondary	Use	(Reuse)	of	Clinical	
Data		
11	|	Publication	and	Peer	Review	
12	|	Information	Retrieval		
13	|	Version	control	and	identiiers		
14	|	Data	annotation	and	curation		
15	|	Data	and	tools	landscape		
16	|	Ontologies	101		
17	|	Data	modeling		
18	|	Data	metadata	and	provenance		
	
Couture Curricula - BD2K Data Science Tailored toYour Needs

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Couture Curricula - BD2K Data Science Tailored to Your Needs

  • 1. William Hersh1, David A. Dorr1,2, Melissa Haendel1,3, Nicole Vasilevsky1,3, Bjorn Pederson1, Jackie Wirz1,3, Shannon McWeeney1 1Department of Medical Informatics and Clinical Epidemiology, 2Department of Medicine, 3Ontology Development Group, Library Oregon Health & Science University, Portland, OR Students felt the course Acknowledgements This work is supported by NIH Grants 1R25EB020379-01 and 1R25GM114820-01. Skills Course Topics Why? Course Offerings Defining The Problem Wrangling Data Methods, Tools And Analysis Scientific Communication Data Identification And Resources … ? v  Problems amenable to analytics v  Importance of question v  Team deinitions v  Scope v  When we do this wrong: methods don't match v  Finding the right data v  Search methods v  Use of metadata v  Data management v Exploratory Data Analysis v Data Dictionary v As you touch data, what can go wrong? v  Visualization v  Matching algorithms to problems v  Reporting Findings and Limitations v  Giving “Elevator Speech” on ideas of how to approach problem v  Critique of related problem Major challenge: how to manage, analyze and interpret vast amounts of data being generated in biomedical research One goal of NIH Big Data to Knowledge (BD2K) initiative: provide training for students and researchers to address this Research team in the Department of Medical Informatics and Clinical Epidemiology (DMICE) is developing skills courses Approach Intro Course Data After Dark OERs and courses connect the dots that help researchers understand how to apply data science techniques in the context of their whole research life cycle §  Skills course and OER topics are aimed to ill speciic gaps §  Teaching students how to ask the question and follow through ① Develop Open Educational Resources (OERS) ② Teach Skills Courses 19 | Semantic data interoperability 20 | Semantic Web data 21 | Context-based selection of data 22 | Translating the Question 23 | Implications of Provenance and Pre-processing 24 | Data tells a story 25 | Choice of Algorithms and Algorithm Dynamics 26 | Statistical Signiicance, P-hacking and Multiple-testing 27 | Displaying Conidence and Uncertainty 28 | Visualization and Interpretation 29 | Replication, Validation and the spectrum of Reproducibility 30 | Regulatory Issues in Big Data for Genomics and Health 31 | Hosting data dissemination and data stewardship workshops 32 | Guidelines for reporting, publications, and data sharing OER Modules Challenges Scope Images Style Dissemination How to scope generic curricula for different levels of users How to translate diverse teaching styles into general materials How to maximize dissemination while protecting intellectual property How to incorporate images and other copyrighted materials into open resources Available at: http://skynet.ohsu.edu/bd2k Advanced Course §  Week long course in Summer 2015 §  Offered to interns and undergraduates §  Taught basics of data science in the context of the research life cycle §  Two-evening course in January 2016 §  Offered to OHSU students, staff and faculty §  Taught basics of data science §  Four-evening course to be offered in May 2016 §  Offered to OHSU students, staff and faculty §  Teach advanced topics in of data science 01 | Biomedical Big Data Science 02 | Introduction to Big Data in Biology and Medicine 03 | Ethical Issues in Use of Big Data 04 | Terminology of Biomedical, Clinical, and Translational Research 05 | Computing Concepts for Big Data 06 | Clinical Data and Standards Related to Big Data 07 | Basic Research Data Standards 08 | Public Health and Big Data 09 | Team Science 10 | Secondary Use (Reuse) of Clinical Data 11 | Publication and Peer Review 12 | Information Retrieval 13 | Version control and identiiers 14 | Data annotation and curation 15 | Data and tools landscape 16 | Ontologies 101 17 | Data modeling 18 | Data metadata and provenance Couture Curricula - BD2K Data Science Tailored toYour Needs