Covid 19 and git
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This presentation summarizes a study on COVID-19 and digestive symptoms. The study included 204 patients in China who tested positive for COVID-19. 18.6% of patients reported digestive symptoms like diarrhea, vomiting, or abdominal pain. Patients with digestive symptoms had more severe disease and took longer to be admitted to the hospital. They were also more likely to have liver injury and receive treatments like antibiotics. However, the study had limitations like its small sample size and lack of testing stool samples for SARS-CoV-2.
![RESULTS
Digestive manifestations:
lack of appetite (81 [78.64%] cases),
diarrhea (35 [34.0%] cases),
vomiting (4 [3.9%] cases), and
abdominal pain (2 [1.9%] cases).
**If the nonspecific symptom of low appetite is
excluded from the analysis, there were 38 total cases
(18.6% of full sample)](https://image.slidesharecdn.com/covid19andgit-200429191429/85/Covid-19-and-git-9-320.jpg)
Covid 19 and git
- 1. JOURNAL CLUB PRESENTAION Hamza Obaid, MD COVID-19 and Digestive Symptoms
- 2. INTHIS PRESENTATION Back ground of the article Methodology used Results Discussion
- 3. BACKGROUND On January 7, 2020, a novel coronavirus was isolated and named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Most patients with COVID-19 have fever along with respiratory signs and symptoms, such as cough and dyspnea Uncertainty about the prevalence of extra pulmonary symptoms, such as those arising from the gastrointestinal tract.
- 4. METHODS Cross-sectional, multicenter study in China from January 18, 2020, to February 28, 2020. Randomly patients with pneumonia of unknown cause from general wards and intensive care units (ICUs)
- 5. METHODS inclusion criteria: (1) all adult patients were confirmed by RT-PCR and were diagnosed as having COVID-19 according toWHO interim guidance (2) all patients who underwent chest computerized tomography (CT) and complete panel of routine laboratory tests: CBC urinalysis blood biochemistry, blood coagulation function
- 6. METHODS 310 • Wards and ICU RT-PCR, CT and Others • Excluded 96 patients 204 • included
- 7. METHODS Patients records Throat swab specimens from the upper respiratory tract for RT-PCR. influenza A virus, influenza B virus, and respiratory syncytial virus were also examined Clinical outcome: combination of -chart review -communication with attending doctors and other medical workers to fill in the missing data. Data collection
- 8. RESULTS
- 9. RESULTS Digestive manifestations: lack of appetite (81 [78.64%] cases), diarrhea (35 [34.0%] cases), vomiting (4 [3.9%] cases), and abdominal pain (2 [1.9%] cases). **If the nonspecific symptom of low appetite is excluded from the analysis, there were 38 total cases (18.6% of full sample)
- 10. RESULTS As the severity of the disease increased, digestive symptoms become more pronounced. Digestive symptoms and time from onset to hospital admission ? (9.0 days vs 7.3 days, P = 0.013) No significant difference in discharge time, days of intensive care, or mortality between the 2 groups.
- 11. RESULTS ALT and AST: ptients with digestive symptoms were more likely to suffer liver injury Monocyte counts were lower in patients with digestive symptoms. No significant differences were found in complete blood count, electrolytes, and kidney function
- 12. RESULTS Patients without digestive symptoms were less likely to receive: antibiotic treatment 62 (61.4%) vs 79 (76.7%), interferon 39 (38.6%) vs 57 (55.3%) Immunoglobulin 17 (16.8%) vs 39 (37.9%).
- 13. LIMITAIONS Based on a retrospective study with a relatively small sample Did not test for RNA of SARS-CoV-2 in the stool of patients with COVID-19, so we cannot correlate digestive symptom prevalence and severity with the presence of viral RNA in stool specimens. Third, blood biochemical examinations are based on a comparison of means in our study that not being subdivided to patients with individual abnormalities.