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CPR Defination
 CPR is a technique through mechanical, physiologic and
pharmacologic methods to resuscitate the individuals in
sudden unexpected death resulting from reversible disease.
 The purpose of CPR is
 To temporarily provide effective oxygenation of vital
organs (especially the brain and heart) until appropriate,
definitive medical treatment can restore normal cardiac
and respiratory activity.
Used alone, CPR will result in few complete recoveries, and those who do survive often develop serious complications.
History of CPR
 The history of CPR and cerebrial arrest
prophylaxis begins in ancient times.
 5000 -first artificial mouth to mouth ventilation in 3000 BC
 1780 – first attempt of newborn resuscitation by blowing
 1874 – first experimental direct cardiac massage
 1901 – first successful direct cardiac massage in man
 1946 – first experimental indirect cardiac massage and
defibrillation
 1960 – indirect cardiac massage
 1980 – development of cardiopulmonary resuscitation due
to the works of Peter Safar
 first International CPR Guidelines in 2000
History of CPR
Inversion method
Silvester’s method of
artificial Ventilation
History of CPR
International Liaison Committee on
Resuscitation (ILCOR)
Formed in 1992 to provide a liaison between
resuscitation organisations worldwide
meets twice a year
ILCOR comprises representatives of
 American Heart Association (AHA)
 European Resuscitation Council (ERC)
 Heart and Stroke Foundation of Canada (HSFC)
 Australian and New Zealand Committee on
Resuscitation (ANZCOR)
 Resuscitation Councils of Southern Africa (RCSA)
 Inter American Heart Foundation (IAHF)
 Resuscitation Council of Asia (RCA)
A FEW HARD FACTS
 330,000 die annually from coronary heart disease
 60% from SCA @ home or en route
 85-90% in VF/VT arrest
 Less than 1/3 get bystander CPR
Even pros don’t do good CPR!
 2-3 x greater survival if CPR is immediate, with
defib <3 min.
 EMS relies on trained, willing, equipped public
Causes of cardiac arrest
Cardiac
 Ischemic heart disease
 Arrhythmias
 Dysectrolytemia
 Valvular disease
 Cardiac tamponade
 Pulmonary
thromboembolism
 Ruptured aneurysm of
aorta
Extracardiac
 Airway obstruction
 Acute respiratory failure
 Shock
 Embolisms of different
origin
 Drug overdose
 Electrocution
 Poisoning
Start CPR Immediately
Better chance of survival
Brain damage starts in 4-6 minutes
Brain damage is certain after 10
minutes without CPR
Even With Successful CPR, Most
Won’t Survive Without ACLS
ACLS includes defibrillation,
oxygen, drug therapy
following abrupt cessation of
effective cardiac output :
Loss on consciousness at about
10~15seconds;
Pupillary dilation at about 30~45
seconds;
Brain damage begins within 4 ~ 6
minutes after cardiac arrest;
Irreversible cerebral cortical damage
occurring within 8~10 minutes after cardiac
arrest.
Diagnosis of cardiac arrest
Absence of pulse on major arteries (carotid or femoral) – a
pathognomonic symptom
cessation of Respirations
with or without pupillary dilatation.
Blood pressure measurement

Taking the pulse on peripheral arteries

Auscultation of cardiac tones
Loss of time !!!
Sudden cardiac death-ECG
The arrest is usuallyassociated with the lethalarrhythmia of ventricular
fibrillation triggered by an acutely ischemic or infarcted myocardium or by a
primary electrical disturbance .
There several ECG in sudden cardiac arrest:
Ventricular fibrillation
Pulseless Ventricular tachycardia
Asystole
Electric –mechanical activity dissociation
Ventricular fibrillation
Asystole
Electric –mechanical activity dissociation
Pulseless Ventricular tachycardia
Post CARDIAC ARREST CARE
New AHA Adult Chain of Survival
New 5th link –post-cardiac arrest care
Links in the new adult Chain of Survival
•Immediate recognition and activation of
emergency response system
•Early CPR, w/emphasis on chest compressions
•Rapid defibrillation
•Effective advanced life support
•Integrated post-cardiac arrest care
Basic Life Support( BLS)
BLS is the application of artificial
ventilation and circulation with or
without special equipment or
drugs to prevent brain damage.
Cpr guide lines
Cpr guide lines
Primary Emphasis on Chest Compressions
All rescuers should, at a minimum, provide
chest compressions.
If bystander not trained (adult arrest): Hands-
Only CPR
If bystander trained and able: perform
compressions and ventilations at rate of 30:2
Healthcare provider: perform compressions and
ventilations at rate of 30:2
For all pediatric arrest, compressions and
ventilations still recommended
C. Circulation
Restore the circulation, that is
start chest compression
2 mechanisms explaining the
restoration of circulation by chest
compression
Cardiac
pump
Thoracic
pump
Cardiac pump during the chest
compression
Blood pumping is assured by the
compression of heart between
sternum and spine
Between compressions
thoracic cage is expanding
and heart is filled with blood
Thoracic pump at chest compression
Blood circulation is restored
because intrathoracic pressure
exceeds extrathoracic vascular
pressure and that flow is restricted
to the venous-to-arterial direction
because of jugular & subclavian
venous valves that prevent
retrograde flow
Compressions
 the victim to lie supine on a hard surface
with the rescuer kneeling beside the
victim’s thorax
 Place heel of one hand on center of chest
between the nipples
 clasping both hands without flexion of
elbow jt., give chest compressions
 For infants: Use the 2 thumb-encircling
technique-sternum compressed with
thumbs and use fingers to squeeze thorax
just below nipple line
 All rescuers should, at a minimum, provide chest
compressions.
 If bystander not trained (adult arrest): Hands-Only
CPR
 If bystander trained and able: perform compressions
and ventilations at rate of 30:2
 Healthcare provider: perform compressions and
ventilations at rate of 30:2
 For all pediatric arrest, compressions and ventilations
still recommended
Primary Emphasis on Chest
Compressions
Adult Chest Compression Depth
 Change: Compress at least 2 inches
2005 recommendation was 1½ to 2 inches.
 Why? Compressions of at least 2 inches are more
effective than those of 1½ inches.
 Rescuers often do not “push hard” enough.
 Confusion may result when range of depth is
recommended.
Chest Compressions Critical
Without effective chest compressions
Oxygen flow to brain stops.
Oxygen flow to heart stops.
Drugs go no where.
Chest Compression Rate
 Change: Compression rate at least 100 per
minute.2005 recommendation: Compression rate
about 100/min
 Why? Absolute number of compressions
delivered/minute has been linked with survival.
 Actual compression rate is often well below
100/min.
A – airway control
In an unconscious patient,
airway obstruction is most
commonly due to
relaxation of the muscles
of the tongue allowing it to
rest against the posterior
pharyngeal wall.
There are several simple
airway maneuver to relieve
this obstruction--opening
the airway method:
if no concern
cervical spine
injury .
Head-tilt/neck
stretch
Head-tilt/chin-lift
if no concern
cervical spine
injury.
patients with
suspected cervical
spine injuries-if
unable to open
airway using the jaw
thrust, use the head-
tilt chin lift
Jaw-thrust
The jaw –
thrust is the
safest method
for opening
the airway if
there is the
possibility of
cervical spine
injury.
Change: This action removed from the CPR sequence
After delivery of 30 compressions, lone rescuer opens
airway and delivers 2 breaths.
Why? Rescuer checks for response and “no breathing or
no normal breathing” in adult before beginning CPR
Starting CPR with compressions minimizes delay to
action
Elimination of “Look, Listen, and
Feel” for Breathing
Pinch the nose- prevent
air escape
take a deep breath
Seal the mouth
give two breaths (1
second or longer)
If the first two
breaths don’t go in, re-
tilt and give two more
breaths (if breaths still
do not go in, suspect
choking)
mouth-to-mouth
 Can’t open mouth
Can’t make a
good seal
Severely injured
mouth
Stomach distension
mouth-to-nose
ventilation may be
more effective.
mouth-to nose
After
tracheotomy ,
the stoma
becomes the
patient’s airway.
mouth-to-stoma
Both mouth to mouth and mouth to
nose ventilation can provide large
volumes,the concentration of oxygen
delivered to the patient is 16%~17%,
may produce an alveolar partial
pressure of oxygen of 80mmHg,more
than enough to patient’s life.
mouth to mask ventilation connected to
high flow oxygen, the concentration of
oxygen is up to 55%。
D-defibrillation
Early defibrillation has emerged as a
single element of BLS that appears to
have the greatest impact on ultimate
survival.
When defibrillation alone is added to the
BLS regimen, survival increases from 6%
to 25% for prehospital VF.
The method of defibrillation
2.Electrical defibrillation :passing an
electrical current through a fibrillating
heart, and causing synchronous
depolarization the disorganized contracting
myofibrils at once, and allowing for uniform
repolarization and subsequent organized
cardiac electromechanical activity.
Electrical Therapies
 Practice needed to minimize interruption in chest
compressions to deliver shock.
 In-hospital use of AEDs may facilitate early
defibrillation (goal: ≤ 3 minutes).
 AEDs can now be used in infants if a manual
defibrillator is not available.
 Defibrillation doses unchanged, adult
cardioversion doses provided
Monophasic vs Biphasic Defibrillators
Automated external defibrillators
(AED)
With a large pads are
currently available.
These machine can
recognize VF and
deliver direct current
(DC) counter shock
with better than 85%
sensitivity and with
100% specificity.
Monophasic vs Biphasic
Defibrillators
 Goal: delivery of current to depolarize myocardial cells and
eliminate VF/VT
 1st-shock efficacy of monophasic < 1st-shock efficacy of biphasic
Monophasic:
 delivers current of one polarity
 dose of 360 J for all shocks
Biphasic:
<200J as safe and w/ higher efficacy than higher voltage in
monophasic
 150 J to 200 J with a biphasic truncated exponential waveform
 120 J with a rectilinear biphasic waveform.
 subsequent shocks: same or higher energy
 CHILD: doses are 2 J/kg for the first attempt and 4 J/kg for
subsequent attempts
Precordial Thump
 The precordial thump should not be used for
unwitnessed out-of-hospital cardiac arrest.
 The precordial thump may be considered for patients
with witnessed, monitored, unstable VT (including
pulseless VT) if a defibrillator is not immediately ready
for use, but it should not delay CPR and shock delivery.
Cpr guide lines
Advanced Life Support-ALS
ALS refers to used special equipment to
manage airway, breathing and circulation
and provide definitive care, including
defibrillation , advanced airway
management, mechanical ventilation and
drug therapy of dysrhythimas and acid-
base disturbance.
Advanced Cardiovascular Life Support
(ACLS)
Foundation of successful ACLS is good
BLS.
Traditional cardiac arrest algorithm
simplified and alternative conceptual
design (both emphasize importance of
high-quality CPR.)
Increased emphasis on continuous
waveform capnography to verify
endotracheal tube placement
optimize CPR quality and detect ROSC.
ACLS: Waveform Capnography
Change: Quantitative waveform
capnography is most reliable method
to confirm and monitor correct ET
tube placement .
Why: Unacceptably high incidence of
unrecognized ET tube misplacement
or displacement.
Capnography has high sensitivity and
specificity to identify correct
endotracheal tube placement in
cardiac arrest.
ACLS: Waveform Capnography
After intubation, exhaled carbon dioxide is
detected, confirming tracheal tube
placement.
Highest value at end-expiration.
ACLS: Physiologic Monitoring During CPR
ACLS: Physiologic Monitoring
During CPR
ACLS: De-emphasis of Devices,
Drugs and other Distracters
 Focus on high-quality CPR and defibrillation
 Atropine no longer recommended for routine use in
management of PEA/asystole.
 Chronotropic drug infusions now recommended as
alternative to pacing in symptomatic and unstable
bradycardia.
 Adenosine recommended as safe and potentially
effective for treatment and diagnosis in initial
management of undifferentiated regular
monomorphic wide-complex tachycardia
ACLS: Medications for Pulseless
Arrest
 Atropine: deleted from pulseless arrest algorithm
 Epinephrine: dose, interval unchanged
 Vasopressin: dose, use unchanged
 Amiodarone: dose, indications unchanged
 Lidocaine: dose, indications unchanged
 Sodium Bicarbonate: Routine use not recommended
(Class III, LOE B).
 Calcium: Routine administration for treatment of
cardiac arrest not recommended (Class III, LOE B).
EPINEPHRINE
 Alpha-adrenergic vasoconstrictor properties increases
coronary and CPP during CPR
 Beta-adrenergic properties controversial - may increase
myocardial workload and reduce subendocardial perfusion
 Converts finer fibrillary waves to coarser ones – more
amenable to defibrillation
 Indication: All cardiac arrest ,VF /VT
 DOSE: 1mg bolus repeated every3-5 min.
 0.0 to 0.03mg/kg, Endotracheal (0.05-0.1 mg)
VASOPRESSIN
 Non-adrenergic peripheral vasoconstrictor
 Retention of water by acting to increase water
absorption in collecting ducts of nephrons.
 The results of coronary perfusion pressure and
ROSC were also slightly better for vasopressin alone
than for epinephrine alone.
 Dose: 40 Units iv to replace the 1st or 2nd dose of
epinephrine.
Amiodarone
 Affects K, Na, Ca-channels, alpha and beta-adrenergic
blocking properties
 Lowers the defibrillation threshold.
 INDICATION: Can be considered if multiple shock
&Epinephrine have fail to revert VF/VT.
 Initial: 300mg slow iv, then 150mg, 5mg/kg.
② Lidocaine
 Actions: Lidocaine is a class IB agent that
depresses myocardial excitability by blocking
sodium channels without extending action
potential duration.
 Indication and dose: The drug is indicated in
Ventricular ectopic, ventricular tachycardia and
ventricular fibrillation that has recurred after a
successful defibrillation or that has been
refractory to defibrillation.
 Dose :In cardiac arrest the recommended dose is
1.5mg/kg bolus repeated in 5~10 min for total
dose of 3mg/kg.
Cpr guide lines
Post-Cardiac Arrest Care
 Change: New 5th link in the chain of survival
 Why: Emphasize importance of comprehensive multidisciplinary care
through hospital discharge and beyond
 Includes: Optimizing vital organ perfusion
 Titration of FiO2 to maintain O2 sat ≥ 94% and < 100%
 Transport to comprehensive post-arrest system of care
 Emergent coronary reperfusion for STEMI or high suspicion of AMI
 Temperature control
 Anticipation, treatment, and prevention of multiple organ dysfunction
Terminating resuscitation in Adult
out side Hospital (BLS)
Arrest not witnessed by first
responder .
No ROSC after 3 complete to CPR
and AED.
No AED shocks delivered.
Terminating resuscitation in Adult
in Hospital (ALS)
Arrest not witnessed by anyone .
No bystander CPR provider.
No shock delivered.
No ROSC after complete ALS
care in field.
Pediatric Resuscitation
Revised pediatric chain
of survival
New post-arrest care link
Paediatric Basic Life Support
 Similarities in paediatric BLS and adult BLSC-A-B
rather than A-B-C sequence
 Continued emphasis on high-quality CPR
 Removal of “look, listen and feel”
 De-emphasis of pulse check for HCPs
 Use AEDs as soon as available
 AEDs may be used in infants, although manual
defibrillation preferred
Pediatric Advanced Life Support
(PALS)
 Optimal energy dose for defibrillation of children
unknown. Initial dose 2-4 J/kg.
 Subsequent dose ≥ 4 J/kg
 Post-ROSC: titrate oxygen to limit hyperoxemia.
 Therapeutic hypothermia (to 32°C to 34°C) may be
beneficial (studies in progress)
 Young victims of sudden, unexpected cardiac arrest
should have a complete autopsy with genetic analysis
of tissue to look for inherited channelopathy.
Neonatal Resuscitation
 For babies born at term, begin resuscitation with room
air rather than 100% oxygen.
 Any oxygen administered should be blended with
room air, titrated based on oxygen saturation
measured from right upper extremity.
 Suctioning after birth reserved for infants with obvious
airway obstruction, those requiring ventilation or non-
vigorous babies with meconium
 Therapeutic hypothermia recommended for babies
near term with evolving moderate to severe hypoxic-
ischemic encephalopathy.
Education, Implementation, and
Teams (EIT)
 New section focusing on methods to improve bystander
willingness to act, education techniques, teamwork and
leadership
 Key Issues: Current 2-year certification period for BLS,
ACLS and PALS should include periodic refresher courses
 Hands-Only CPR should be taught
 Practice-while-watching is effective for BLS
 Training should not be required for lay rescuers but it does
improve performance
 Debriefing is effective
Summary of 2010 Guidelines
 Many resuscitation systems and communities have
documented improved survival from cardiac arrest.
 Too few victims of cardiac arrest receive bystander CPR.
 CPR quality must be high.
 Victims require excellent post–cardiac arrest care by
organized, integrated teams.
 Education and frequent refresher training key to improving
resuscitation performance.
 We must rededicate ourselves to improving the frequency
of bystander CPR, the quality of all CPR and the quality of
post–cardiac arrest care.
Type of Arrest ROSC Survival
Witnessed In-Hospital Cardiac Arrest 48%
22%40%
Unwitnessed In-Hospital Cardiac Arrest 21% 1%
Bystander compression-only Resuscitation 6%
Bystander Cardiopulmonary Resuscitation 40% 4%
No Bystander CPR (Ambulance CPR) 15% 2%
Defibrillation within 3–5 minutes 74% 30%
Thank you
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Cpr guide lines

  • 1. CPR Defination  CPR is a technique through mechanical, physiologic and pharmacologic methods to resuscitate the individuals in sudden unexpected death resulting from reversible disease.
  • 2.  The purpose of CPR is  To temporarily provide effective oxygenation of vital organs (especially the brain and heart) until appropriate, definitive medical treatment can restore normal cardiac and respiratory activity. Used alone, CPR will result in few complete recoveries, and those who do survive often develop serious complications.
  • 3. History of CPR  The history of CPR and cerebrial arrest prophylaxis begins in ancient times.  5000 -first artificial mouth to mouth ventilation in 3000 BC  1780 – first attempt of newborn resuscitation by blowing  1874 – first experimental direct cardiac massage  1901 – first successful direct cardiac massage in man  1946 – first experimental indirect cardiac massage and defibrillation  1960 – indirect cardiac massage  1980 – development of cardiopulmonary resuscitation due to the works of Peter Safar  first International CPR Guidelines in 2000
  • 4. History of CPR Inversion method Silvester’s method of artificial Ventilation
  • 6. International Liaison Committee on Resuscitation (ILCOR) Formed in 1992 to provide a liaison between resuscitation organisations worldwide meets twice a year ILCOR comprises representatives of  American Heart Association (AHA)  European Resuscitation Council (ERC)  Heart and Stroke Foundation of Canada (HSFC)  Australian and New Zealand Committee on Resuscitation (ANZCOR)  Resuscitation Councils of Southern Africa (RCSA)  Inter American Heart Foundation (IAHF)  Resuscitation Council of Asia (RCA)
  • 7. A FEW HARD FACTS  330,000 die annually from coronary heart disease  60% from SCA @ home or en route  85-90% in VF/VT arrest  Less than 1/3 get bystander CPR Even pros don’t do good CPR!  2-3 x greater survival if CPR is immediate, with defib <3 min.  EMS relies on trained, willing, equipped public
  • 8. Causes of cardiac arrest Cardiac  Ischemic heart disease  Arrhythmias  Dysectrolytemia  Valvular disease  Cardiac tamponade  Pulmonary thromboembolism  Ruptured aneurysm of aorta Extracardiac  Airway obstruction  Acute respiratory failure  Shock  Embolisms of different origin  Drug overdose  Electrocution  Poisoning
  • 9. Start CPR Immediately Better chance of survival Brain damage starts in 4-6 minutes Brain damage is certain after 10 minutes without CPR Even With Successful CPR, Most Won’t Survive Without ACLS ACLS includes defibrillation, oxygen, drug therapy
  • 10. following abrupt cessation of effective cardiac output : Loss on consciousness at about 10~15seconds; Pupillary dilation at about 30~45 seconds; Brain damage begins within 4 ~ 6 minutes after cardiac arrest; Irreversible cerebral cortical damage occurring within 8~10 minutes after cardiac arrest.
  • 11. Diagnosis of cardiac arrest Absence of pulse on major arteries (carotid or femoral) – a pathognomonic symptom cessation of Respirations with or without pupillary dilatation. Blood pressure measurement  Taking the pulse on peripheral arteries  Auscultation of cardiac tones Loss of time !!!
  • 12. Sudden cardiac death-ECG The arrest is usuallyassociated with the lethalarrhythmia of ventricular fibrillation triggered by an acutely ischemic or infarcted myocardium or by a primary electrical disturbance . There several ECG in sudden cardiac arrest: Ventricular fibrillation Pulseless Ventricular tachycardia Asystole Electric –mechanical activity dissociation
  • 13. Ventricular fibrillation Asystole Electric –mechanical activity dissociation Pulseless Ventricular tachycardia
  • 15. New AHA Adult Chain of Survival New 5th link –post-cardiac arrest care Links in the new adult Chain of Survival •Immediate recognition and activation of emergency response system •Early CPR, w/emphasis on chest compressions •Rapid defibrillation •Effective advanced life support •Integrated post-cardiac arrest care
  • 16. Basic Life Support( BLS) BLS is the application of artificial ventilation and circulation with or without special equipment or drugs to prevent brain damage.
  • 19. Primary Emphasis on Chest Compressions All rescuers should, at a minimum, provide chest compressions. If bystander not trained (adult arrest): Hands- Only CPR If bystander trained and able: perform compressions and ventilations at rate of 30:2 Healthcare provider: perform compressions and ventilations at rate of 30:2 For all pediatric arrest, compressions and ventilations still recommended
  • 20. C. Circulation Restore the circulation, that is start chest compression
  • 21. 2 mechanisms explaining the restoration of circulation by chest compression Cardiac pump Thoracic pump
  • 22. Cardiac pump during the chest compression Blood pumping is assured by the compression of heart between sternum and spine Between compressions thoracic cage is expanding and heart is filled with blood
  • 23. Thoracic pump at chest compression Blood circulation is restored because intrathoracic pressure exceeds extrathoracic vascular pressure and that flow is restricted to the venous-to-arterial direction because of jugular & subclavian venous valves that prevent retrograde flow
  • 24. Compressions  the victim to lie supine on a hard surface with the rescuer kneeling beside the victim’s thorax  Place heel of one hand on center of chest between the nipples  clasping both hands without flexion of elbow jt., give chest compressions  For infants: Use the 2 thumb-encircling technique-sternum compressed with thumbs and use fingers to squeeze thorax just below nipple line
  • 25.  All rescuers should, at a minimum, provide chest compressions.  If bystander not trained (adult arrest): Hands-Only CPR  If bystander trained and able: perform compressions and ventilations at rate of 30:2  Healthcare provider: perform compressions and ventilations at rate of 30:2  For all pediatric arrest, compressions and ventilations still recommended Primary Emphasis on Chest Compressions
  • 26. Adult Chest Compression Depth  Change: Compress at least 2 inches 2005 recommendation was 1½ to 2 inches.  Why? Compressions of at least 2 inches are more effective than those of 1½ inches.  Rescuers often do not “push hard” enough.  Confusion may result when range of depth is recommended.
  • 27. Chest Compressions Critical Without effective chest compressions Oxygen flow to brain stops. Oxygen flow to heart stops. Drugs go no where.
  • 28. Chest Compression Rate  Change: Compression rate at least 100 per minute.2005 recommendation: Compression rate about 100/min  Why? Absolute number of compressions delivered/minute has been linked with survival.  Actual compression rate is often well below 100/min.
  • 29. A – airway control In an unconscious patient, airway obstruction is most commonly due to relaxation of the muscles of the tongue allowing it to rest against the posterior pharyngeal wall.
  • 30. There are several simple airway maneuver to relieve this obstruction--opening the airway method:
  • 31. if no concern cervical spine injury . Head-tilt/neck stretch
  • 32. Head-tilt/chin-lift if no concern cervical spine injury. patients with suspected cervical spine injuries-if unable to open airway using the jaw thrust, use the head- tilt chin lift
  • 33. Jaw-thrust The jaw – thrust is the safest method for opening the airway if there is the possibility of cervical spine injury.
  • 34. Change: This action removed from the CPR sequence After delivery of 30 compressions, lone rescuer opens airway and delivers 2 breaths. Why? Rescuer checks for response and “no breathing or no normal breathing” in adult before beginning CPR Starting CPR with compressions minimizes delay to action Elimination of “Look, Listen, and Feel” for Breathing
  • 35. Pinch the nose- prevent air escape take a deep breath Seal the mouth give two breaths (1 second or longer) If the first two breaths don’t go in, re- tilt and give two more breaths (if breaths still do not go in, suspect choking) mouth-to-mouth
  • 36.  Can’t open mouth Can’t make a good seal Severely injured mouth Stomach distension mouth-to-nose ventilation may be more effective. mouth-to nose
  • 37. After tracheotomy , the stoma becomes the patient’s airway. mouth-to-stoma
  • 38. Both mouth to mouth and mouth to nose ventilation can provide large volumes,the concentration of oxygen delivered to the patient is 16%~17%, may produce an alveolar partial pressure of oxygen of 80mmHg,more than enough to patient’s life. mouth to mask ventilation connected to high flow oxygen, the concentration of oxygen is up to 55%。
  • 39. D-defibrillation Early defibrillation has emerged as a single element of BLS that appears to have the greatest impact on ultimate survival. When defibrillation alone is added to the BLS regimen, survival increases from 6% to 25% for prehospital VF.
  • 40. The method of defibrillation 2.Electrical defibrillation :passing an electrical current through a fibrillating heart, and causing synchronous depolarization the disorganized contracting myofibrils at once, and allowing for uniform repolarization and subsequent organized cardiac electromechanical activity.
  • 41. Electrical Therapies  Practice needed to minimize interruption in chest compressions to deliver shock.  In-hospital use of AEDs may facilitate early defibrillation (goal: ≤ 3 minutes).  AEDs can now be used in infants if a manual defibrillator is not available.  Defibrillation doses unchanged, adult cardioversion doses provided
  • 42. Monophasic vs Biphasic Defibrillators
  • 43. Automated external defibrillators (AED) With a large pads are currently available. These machine can recognize VF and deliver direct current (DC) counter shock with better than 85% sensitivity and with 100% specificity.
  • 44. Monophasic vs Biphasic Defibrillators  Goal: delivery of current to depolarize myocardial cells and eliminate VF/VT  1st-shock efficacy of monophasic < 1st-shock efficacy of biphasic Monophasic:  delivers current of one polarity  dose of 360 J for all shocks Biphasic: <200J as safe and w/ higher efficacy than higher voltage in monophasic  150 J to 200 J with a biphasic truncated exponential waveform  120 J with a rectilinear biphasic waveform.  subsequent shocks: same or higher energy  CHILD: doses are 2 J/kg for the first attempt and 4 J/kg for subsequent attempts
  • 45. Precordial Thump  The precordial thump should not be used for unwitnessed out-of-hospital cardiac arrest.  The precordial thump may be considered for patients with witnessed, monitored, unstable VT (including pulseless VT) if a defibrillator is not immediately ready for use, but it should not delay CPR and shock delivery.
  • 47. Advanced Life Support-ALS ALS refers to used special equipment to manage airway, breathing and circulation and provide definitive care, including defibrillation , advanced airway management, mechanical ventilation and drug therapy of dysrhythimas and acid- base disturbance.
  • 48. Advanced Cardiovascular Life Support (ACLS) Foundation of successful ACLS is good BLS. Traditional cardiac arrest algorithm simplified and alternative conceptual design (both emphasize importance of high-quality CPR.) Increased emphasis on continuous waveform capnography to verify endotracheal tube placement optimize CPR quality and detect ROSC.
  • 49. ACLS: Waveform Capnography Change: Quantitative waveform capnography is most reliable method to confirm and monitor correct ET tube placement . Why: Unacceptably high incidence of unrecognized ET tube misplacement or displacement. Capnography has high sensitivity and specificity to identify correct endotracheal tube placement in cardiac arrest.
  • 50. ACLS: Waveform Capnography After intubation, exhaled carbon dioxide is detected, confirming tracheal tube placement. Highest value at end-expiration.
  • 51. ACLS: Physiologic Monitoring During CPR ACLS: Physiologic Monitoring During CPR
  • 52. ACLS: De-emphasis of Devices, Drugs and other Distracters  Focus on high-quality CPR and defibrillation  Atropine no longer recommended for routine use in management of PEA/asystole.  Chronotropic drug infusions now recommended as alternative to pacing in symptomatic and unstable bradycardia.  Adenosine recommended as safe and potentially effective for treatment and diagnosis in initial management of undifferentiated regular monomorphic wide-complex tachycardia
  • 53. ACLS: Medications for Pulseless Arrest  Atropine: deleted from pulseless arrest algorithm  Epinephrine: dose, interval unchanged  Vasopressin: dose, use unchanged  Amiodarone: dose, indications unchanged  Lidocaine: dose, indications unchanged  Sodium Bicarbonate: Routine use not recommended (Class III, LOE B).  Calcium: Routine administration for treatment of cardiac arrest not recommended (Class III, LOE B).
  • 54. EPINEPHRINE  Alpha-adrenergic vasoconstrictor properties increases coronary and CPP during CPR  Beta-adrenergic properties controversial - may increase myocardial workload and reduce subendocardial perfusion  Converts finer fibrillary waves to coarser ones – more amenable to defibrillation  Indication: All cardiac arrest ,VF /VT  DOSE: 1mg bolus repeated every3-5 min.  0.0 to 0.03mg/kg, Endotracheal (0.05-0.1 mg)
  • 55. VASOPRESSIN  Non-adrenergic peripheral vasoconstrictor  Retention of water by acting to increase water absorption in collecting ducts of nephrons.  The results of coronary perfusion pressure and ROSC were also slightly better for vasopressin alone than for epinephrine alone.  Dose: 40 Units iv to replace the 1st or 2nd dose of epinephrine.
  • 56. Amiodarone  Affects K, Na, Ca-channels, alpha and beta-adrenergic blocking properties  Lowers the defibrillation threshold.  INDICATION: Can be considered if multiple shock &Epinephrine have fail to revert VF/VT.  Initial: 300mg slow iv, then 150mg, 5mg/kg.
  • 57. ② Lidocaine  Actions: Lidocaine is a class IB agent that depresses myocardial excitability by blocking sodium channels without extending action potential duration.  Indication and dose: The drug is indicated in Ventricular ectopic, ventricular tachycardia and ventricular fibrillation that has recurred after a successful defibrillation or that has been refractory to defibrillation.  Dose :In cardiac arrest the recommended dose is 1.5mg/kg bolus repeated in 5~10 min for total dose of 3mg/kg.
  • 59. Post-Cardiac Arrest Care  Change: New 5th link in the chain of survival  Why: Emphasize importance of comprehensive multidisciplinary care through hospital discharge and beyond  Includes: Optimizing vital organ perfusion  Titration of FiO2 to maintain O2 sat ≥ 94% and < 100%  Transport to comprehensive post-arrest system of care  Emergent coronary reperfusion for STEMI or high suspicion of AMI  Temperature control  Anticipation, treatment, and prevention of multiple organ dysfunction
  • 60. Terminating resuscitation in Adult out side Hospital (BLS) Arrest not witnessed by first responder . No ROSC after 3 complete to CPR and AED. No AED shocks delivered.
  • 61. Terminating resuscitation in Adult in Hospital (ALS) Arrest not witnessed by anyone . No bystander CPR provider. No shock delivered. No ROSC after complete ALS care in field.
  • 62. Pediatric Resuscitation Revised pediatric chain of survival New post-arrest care link
  • 63. Paediatric Basic Life Support  Similarities in paediatric BLS and adult BLSC-A-B rather than A-B-C sequence  Continued emphasis on high-quality CPR  Removal of “look, listen and feel”  De-emphasis of pulse check for HCPs  Use AEDs as soon as available  AEDs may be used in infants, although manual defibrillation preferred
  • 64. Pediatric Advanced Life Support (PALS)  Optimal energy dose for defibrillation of children unknown. Initial dose 2-4 J/kg.  Subsequent dose ≥ 4 J/kg  Post-ROSC: titrate oxygen to limit hyperoxemia.  Therapeutic hypothermia (to 32°C to 34°C) may be beneficial (studies in progress)  Young victims of sudden, unexpected cardiac arrest should have a complete autopsy with genetic analysis of tissue to look for inherited channelopathy.
  • 65. Neonatal Resuscitation  For babies born at term, begin resuscitation with room air rather than 100% oxygen.  Any oxygen administered should be blended with room air, titrated based on oxygen saturation measured from right upper extremity.  Suctioning after birth reserved for infants with obvious airway obstruction, those requiring ventilation or non- vigorous babies with meconium  Therapeutic hypothermia recommended for babies near term with evolving moderate to severe hypoxic- ischemic encephalopathy.
  • 66. Education, Implementation, and Teams (EIT)  New section focusing on methods to improve bystander willingness to act, education techniques, teamwork and leadership  Key Issues: Current 2-year certification period for BLS, ACLS and PALS should include periodic refresher courses  Hands-Only CPR should be taught  Practice-while-watching is effective for BLS  Training should not be required for lay rescuers but it does improve performance  Debriefing is effective
  • 67. Summary of 2010 Guidelines  Many resuscitation systems and communities have documented improved survival from cardiac arrest.  Too few victims of cardiac arrest receive bystander CPR.  CPR quality must be high.  Victims require excellent post–cardiac arrest care by organized, integrated teams.  Education and frequent refresher training key to improving resuscitation performance.  We must rededicate ourselves to improving the frequency of bystander CPR, the quality of all CPR and the quality of post–cardiac arrest care.
  • 68. Type of Arrest ROSC Survival Witnessed In-Hospital Cardiac Arrest 48% 22%40% Unwitnessed In-Hospital Cardiac Arrest 21% 1% Bystander compression-only Resuscitation 6% Bystander Cardiopulmonary Resuscitation 40% 4% No Bystander CPR (Ambulance CPR) 15% 2% Defibrillation within 3–5 minutes 74% 30%