Cross tabulation tests whether a relationship exists between two variables in a dataset. It examines if there are any differences or similarities in responses between the variables. Chi-square tests whether this relationship is statistically significant. It requires at least 50 cases in each sub-group and no more than 20% of cells with less than 5 expected responses. Running a cross tab produces a chi-square value and p-value to determine if the relationship is significant at the 0.05 level, meaning the variables are associated rather than independent.